Gene name: CNR1
Protein name: Cannabinoid receptor 1
List of molecules and drugs that interact with protein P21554
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P21554_7DY | 7DY | DB06624 | 11226090 | CHEMBL220360 | N-[(2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide | antagonist | |
| 2 | P21554_7IC | 7IC | n/a | 129407013 | n/a | 6-methyl-3-[(1S)-2-nitro-1-thiophen-2-yl-ethyl]-2-phenyl-1H-indole | n/a | |
| 3 | P21554_8D0 | 8D0 | n/a | 102336704 | CHEMBL5085420 | (6~{a}~{R},9~{R},10~{a}~{R})-9-(hydroxymethyl)-3-(8-isothiocyanato-2-methyl-octan-2-yl)-6,6-dimethyl-6~{a},7,8,9,10,10~{a}-hexahydrobenzo[c]chromen-1-ol | n/a | |
| 4 | P21554_8D3 | 8D3 | n/a | 53318931 | CHEMBL1683648 | (6aR,10aR)-3-(8-bromanyl-2-methyl-octan-2-yl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol | n/a | |
| 5 | P21554_9GF | 9GF | n/a | 104895 | CHEMBL559612 | 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol | n/a | |
| 6 | P21554_9GL | 9GL | n/a | 44828492 | CHEMBL1553629 | 5-chloro-3-ethyl-N-{2-[4-(piperidin-1-yl)phenyl]ethyl}-1H-indole-2-carboxamide | n/a | |
| 7 | P21554_CLR | CLR | DB04540 | 5997 | CHEMBL112570 | CHOLESTEROL | n/a | |
| 8 | P21554_FMN | FMN | DB03247 | 643976 | CHEMBL1201794 | FLAVIN MONONUCLEOTIDE | n/a | |
| 9 | P21554_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 10 | P21554_KCA | KCA | n/a | 119025665 | n/a | methyl N-{1-[(4-fluorophenyl)methyl]-1H-indazole-3-carbonyl}-3-methyl-L-valinate | n/a | |
| 11 | P21554_OLA | OLA | n/a | 445639 | CHEMBL8659 | OLEIC ACID | n/a | |
| 12 | P21554_OLC | OLC | n/a | 11451146 | n/a | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | n/a | |
| 13 | P21554_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 14 | P21554_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 15 | P21554_ZDG | ZDG | n/a | 46912833 | CHEMBL5267903 | 4-[4-[2-(2,4-dichlorophenyl)-4-methyl-5-(piperidin-1-ylcarbamoyl)pyrazol-3-yl]phenyl]but-3-ynyl nitrate | n/a | |
| 16 | P21554_TCI | TCI | DB00470 | 16078 | CHEMBL465 | Dronabinol | agonist | Ki(nM) = 2.9 IC50(nM) = 2.8 EC50(nM) = 17.0 |
| 17 | P21554_DB00486 | n/a | DB00486 | n/a | n/a | Nabilone | partial agonist | Ki(nM) = 2.2 |
| 18 | P21554_DB02955 | n/a | DB02955 | n/a | n/a | Ricinoleic acid | n/a | |
| 19 | P21554_AY6 | AY6 | DB06155 | 104850 | CHEMBL111 | Rimonabant | antagonist | Ki(nM) = 0.4 IC50(nM) = 1.35 Kd(nM) = 1.8 EC50(nM) = 0.11 |
| 20 | P21554_P0T | P0T | DB09061 | 644019 | CHEMBL190461 | Cannabidiol | antagonist | |
| 21 | P21554_DB09288 | n/a | DB09288 | n/a | n/a | Propacetamol | antagonist | |
| 22 | P21554_DB11745 | n/a | DB11745 | n/a | n/a | Otenabant | antagonist | |
| 23 | P21554_DB11755 | n/a | DB11755 | n/a | n/a | Tetrahydrocannabivarin | antagonist | |
| 24 | P21554_DB14011 | n/a | DB14011 | n/a | n/a | Nabiximols | n/a |