Gene name: TAF1
Protein name: Transcription initiation factor
List of molecules and drugs that interact with protein P21675
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P21675_06M | 06M | n/a | 155923693 | n/a | 6-(but-3-en-1-yl)-4-[6-{1-[(R)-S-methanesulfonimidoyl]cyclopropyl}-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one | n/a | |
| 2 | P21675_5LV | 5LV | n/a | 156613431 | CHEMBL4860188 | 8-[[1-(3-azanylpropyl)piperidin-4-yl]amino]-5-[5-(hydroxymethyl)pyridin-3-yl]-3-methyl-1~{H}-1,7-naphthyridin-2-one | n/a | |
| 3 | P21675_67B | 67B | n/a | 119081692 | CHEMBL4436408 | N,N-dimethyl-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)benzamide | n/a | |
| 4 | P21675_67C | 67C | n/a | 119081691 | CHEMBL4436158 | 3-[6-(but-3-en-1-yl)-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl]-N,N-dimethylbenzamide | n/a | |
| 5 | P21675_69G | 69G | n/a | 121335190 | CHEMBL4519632 | 3-{6-[(2E)-but-2-en-1-yl]-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl}-N,N-dimethylbenzamide | n/a | |
| 6 | P21675_7M8 | 7M8 | n/a | 122705990 | CHEMBL4086276 | 6-(3-oxidanylpropyl)-2-(1,3,6-trimethyl-2-oxidanylidene-benzimidazol-5-yl)benzo[de]isoquinoline-1,3-dione | n/a | |
| 7 | P21675_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 8 | P21675_BMF | BMF | n/a | 72943187 | CHEMBL3133807 | Bromosporine | n/a | |
| 9 | P21675_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 10 | P21675_DIO | DIO | DB03316 | 31275 | CHEMBL453716 | 1,4-DIETHYLENE DIOXIDE | n/a | |
| 11 | P21675_DKH | DKH | n/a | n/a | n/a | 3-azanyl-2-[3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[[3-azanyl-1-[[2-[[3-methyl-6-[4-methyl-3-(methylsulfonyl-$l^{2}-azanyl)cyclohexa-1,3,5-trien-1-yl]-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]-$l^{2}-azanyl]-2-oxidanylidene-ethyl]amino]-1-oxidanylidene-propan-2-yl]amino]-2-oxidanylidene-ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-~{N}-[3-[[3-methyl-6-[4-methyl-3-(methylsulfonylamino)phenyl]-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]amino]-3-oxidanylidene-propyl]propanamide | n/a | |
| 12 | P21675_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 13 | P21675_E9F | E9F | n/a | 162422441 | n/a | 4-(6-{1-[(R)-S-methanesulfonimidoyl]cyclopropyl}-2-[(3R)-3-methylmorpholin-4-yl]pyrimidin-4-yl)-1H-pyrrolo[2,3-b]pyridine | n/a | |
| 14 | P21675_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 15 | P21675_EIO | EIO | n/a | n/a | n/a | (3R)-4-[6-{1-[diamino(hydroxy)-lambda~4~-sulfanyl]cyclopropyl}-2-(methylsulfanyl)pyrimidin-4-yl]-3-methylmorpholine | n/a | |
| 16 | P21675_FMT | FMT | DB01942 | 284;18971002; | CHEMBL116736 | FORMIC ACID | n/a | |
| 17 | P21675_G9V | G9V | n/a | 121335283 | CHEMBL4463538 | 6-(but-3-en-1-yl)-4-[1-methyl-6-(morpholine-4-carbonyl)-1H-benzimidazol-4-yl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one | n/a | |
| 18 | P21675_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 19 | P21675_HEZ | HEZ | DB02210 | 12374 | CHEMBL458616 | HEXANE-1,6-DIOL | n/a | |
| 20 | P21675_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 21 | P21675_NQP | NQP | n/a | 146037610 | CHEMBL4474288 | 4-{[(3R)-1-(but-3-en-1-yl)-3-methyl-4-(oxan-4-yl)-2-oxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-6-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide | n/a | |
| 22 | P21675_NQV | NQV | n/a | 146037608 | CHEMBL4539891 | 4-{[(3R)-4-cyclopentyl-1,3-dimethyl-2-oxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-6-yl]amino}-N-(1-methylpiperidin-4-yl)-3-[(propan-2-yl)oxy]benzamide | n/a | |
| 23 | P21675_NQY | NQY | n/a | 146037609 | CHEMBL4573352 | 3-methoxy-4-{[(6aR)-5-methyl-6-oxo-6,6a,7,8,9,10-hexahydro-5H-dipyrido[1,2-a:3',2'-e]pyrazin-2-yl]amino}-N-(1-methylpiperidin-4-yl)benzamide | n/a | |
| 24 | P21675_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 25 | P21675_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 26 | P21675_R78 | R78 | DB16107 | 11364421 | CHEMBL513909 | 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide | n/a | |
| 27 | P21675_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 28 | P21675_TRS | TRS | DB03754 | 3777159;88088752;152743085; | n/a | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 29 | P21675_VCD | VCD | n/a | 46244454 | CHEMBL2325697 | 4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1H-indole | n/a | |
| 30 | P21675_VJM | VJM | n/a | 156587348 | n/a | 4-(4-{1-[(R)-amino(hydroxy)methyl-lambda~4~-sulfanyl]cyclopropyl}-6-[(3R)-3-methylmorpholin-4-yl]pyrimidin-2-yl)-1H-pyrrolo[2,3-b]pyridine | n/a | |
| 31 | P21675_VK1 | VK1 | n/a | 156587349 | n/a | 1-{6-[(3R)-3-methylmorpholin-4-yl]-2-(methylsulfanyl)pyrimidin-4-yl}cyclopropane-1-sulfonimidoamide | n/a | |
| 32 | P21675_VQS | VQS | n/a | 25168990 | CHEMBL3410672 | N-(4-{4-[1-(cyclopropylsulfonyl)cyclopropyl]-6-[(3S)-3-methylmorpholin-4-yl]pyrimidin-2-yl}phenyl)-N'-(2-hydroxyethyl)thiourea | n/a | |
| 33 | P21675_XWV | XWV | n/a | 155937489 | n/a | 5-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-(S-methylsulfonimidoyl)cyclopropyl]pyrimidin-2-yl}isoquinoline | n/a | |
| 34 | P21675_XWY | XWY | n/a | 155937490 | n/a | (3R)-3-methyl-4-{6-[1-(S-methylsulfonimidoyl)cyclopropyl]-2-(naphthalen-1-yl)pyrimidin-4-yl}morpholine | n/a | |
| 35 | P21675_XXS | XXS | n/a | 162394538 | n/a | 4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-(S-methylsulfonimidoyl)cyclopropyl]pyrimidin-2-yl}-1H-indazole | n/a | |
| 36 | P21675_XXV | XXV | n/a | 155937488 | n/a | 1-{6-[(3R)-3-methylmorpholin-4-yl]-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl}cyclopropane-1-sulfonamide | n/a |