Gene name: FGFR3
Protein name: Fibroblast growth factor
List of molecules and drugs that interact with protein P22607
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P22607_ACP | ACP | DB03909 | 91532 | CHEMBL133463 | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | n/a | |
| 2 | P22607_CU | CU | n/a | 27099 | n/a | COPPER (II) ION | n/a | |
| 3 | P22607_EVR | EVR | n/a | 146018255 | CHEMBL4634918 | 2-[[5-[2-(3,5-dimethoxyphenyl)ethyl]-2-[[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]pyrimidin-4-yl]amino]-N-ethyl-benzenesulfonamide | n/a | |
| 4 | P22607_H6X | H6X | n/a | 86719235 | CHEMBL4756275 | 5-[2-(3,5-dimethoxyphenyl)ethyl]-N-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-2-amine | n/a | |
| 5 | P22607_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 6 | P22607_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 7 | P22607_DB06589 | n/a | DB06589 | n/a | n/a | Pazopanib | inhibitor | Kd(nM) = 620.0 |
| 8 | P22607_0LI | 0LI | DB08901 | 24826799 | CHEMBL1171837 | Ponatinib | inhibitor | IC50(nM) = 9.4 |
| 9 | P22607_LEV | LEV | DB09078 | 9823820 | CHEMBL1289601 | Lenvatinib | inhibitor | |
| 10 | P22607_XIN | XIN | DB09079 | 9809715 | CHEMBL502835 | Nintedanib | inhibitor | |
| 11 | P22607_07J | 07J | DB11886 | 53235510 | CHEMBL1852688 | Infigratinib | inhibitor | |
| 12 | P22607_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor | |
| 13 | P22607_5SF | 5SF | DB12147 | 67462786 | CHEMBL3545376 | Erdafitinib | inhibitor | |
| 14 | P22607_8ZF | 8ZF | DB15102 | 86705695 | CHEMBL4297522 | Pemigatinib | inhibitor | |
| 15 | P22607_TZ0 | TZ0 | DB15149 | 71621331 | CHEMBL3701238 | Futibatinib | inhibitor | |
| 16 | P22607_DB15685 | n/a | DB15685 | n/a | n/a | Selpercatinib | inhibitor |