Gene name: CA4
Protein name: Carbonic anhydrase 4
List of molecules and drugs that interact with protein P22748
# | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
---|---|---|---|---|---|---|---|---|
1 | P22748_6CC | 6CC | n/a | 124222720 | n/a | 5-(2-amino-1,3-thiazol-4-yl)-2-chlorobenzene-1-sulfonamide | n/a | |
2 | P22748_6LH | 6LH | DB06795 | 3998 | CHEMBL419 | 4-(aminomethyl)benzene-1-sulfonamide | inhibitor | Ki(nM) = 2800.0 |
3 | P22748_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
4 | P22748_AG4 | AG4 | n/a | 44201383 | CHEMBL1099124 | N-(3-methoxypropyl)-2-(phenylsulfanyl)-5-sulfamoylpyridine-3-carboxamide | n/a | |
5 | P22748_AG5 | AG5 | n/a | 44201382 | CHEMBL1094898 | N-(2-phenylethyl)-2-(phenylsulfanyl)-5-sulfamoylpyridine-3-carboxamide | n/a | |
6 | P22748_AZM | AZM | DB00819 | 1986 | CHEMBL20 | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE | inhibitor | Ki(nM) = 8.6 IC50(nM) = 17.5 Kd(nM) = 12.0 |
7 | P22748_ETS | ETS | DB00869 | 5284549 | CHEMBL218490 | (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE | inhibitor | Ki(nM) = 43.0 IC50(nM) = 32.0 |
8 | P22748_EZL | EZL | DB00311 | 3295 | CHEMBL18 | 6-ethoxy-1,3-benzothiazole-2-sulfonamide | inhibitor | Ki(nM) = 93.0 |
9 | P22748_GLC | GLC | n/a | 79025 | CHEMBL423707 | alpha-D-glucopyranose | n/a | |
10 | P22748_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
11 | P22748_MZM | MZM | n/a | 5353756 | n/a | N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide | n/a | |
12 | P22748_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
13 | P22748_TOR | TOR | DB00273 | 5284627 | CHEMBL220492 | [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate | inhibitor | Ki(nM) = 4900.0 |
14 | P22748_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
15 | P22748_DB00232 | n/a | DB00232 | n/a | n/a | Methyclothiazide | inhibitor | |
16 | P22748_DB00436 | n/a | DB00436 | n/a | n/a | Bendroflumethiazide | inhibitor | |
17 | P22748_DB00562 | n/a | DB00562 | n/a | n/a | Benzthiazide | inhibitor | |
18 | P22748_DB00703 | n/a | DB00703 | n/a | n/a | Methazolamide | inhibitor | |
19 | P22748_HFZ | HFZ | DB00774 | 3647 | CHEMBL1763 | Hydroflumethiazide | inhibitor | Ki(nM) = 4780.0 |
20 | P22748_ZON | ZON | DB00909 | 5734;11967800; | CHEMBL750 | Zonisamide | inhibitor | Ki(nM) = 8590.0 |
21 | P22748_DB01021 | n/a | DB01021 | n/a | n/a | Trichlormethiazide | inhibitor | Ki(nM) = 449.0 |
22 | P22748_I7A | I7A | DB01144 | 3038 | CHEMBL17 | Diclofenamide | inhibitor | Ki(nM) = 95.0 |
23 | P22748_BZ1 | BZ1 | DB01194 | 68844 | CHEMBL220491 | Brinzolamide | inhibitor | Ki(nM) = 3950.0 IC50(nM) = 45.0 |
24 | P22748_REF | REF | DB08846 | 5281855 | CHEMBL6246 | Ellagic acid | inhibitor | |
25 | P22748_DB09460 | n/a | DB09460 | n/a | n/a | Sodium carbonate | inhibitor |