Gene name: Grik1
Protein name: Glutamate receptor ionotropic,
List of molecules and drugs that interact with protein P22756
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P22756_1PE | 1PE | n/a | 62551 | CHEMBL1229766 | PENTAETHYLENE GLYCOL | n/a | |
| 2 | P22756_2J9 | 2J9 | n/a | 67531324 | CHEMBL2441067 | 4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide | n/a | |
| 3 | P22756_35K | 35K | n/a | 137348123 | CHEMBL5177751 | (2S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid | n/a | |
| 4 | P22756_3HU | 3HU | n/a | 24850183 | CHEMBL1738726 | (S)-1-(2'-AMINO-2'-CARBOXYETHYL)-3-[(2-CARBOXYTHIEN-3-YL)METHYL]THIENO[3,4-D]PYRIMIDIN-2,4-DIONE | n/a | |
| 5 | P22756_4E7 | 4E7 | n/a | 91826024 | n/a | (3R,4S)-3-(3-carboxyphenyl)-4-propyl-L-proline | n/a | |
| 6 | P22756_5PX | 5PX | n/a | 67305878 | n/a | 4-Cyclopropyl-3,4-dihydro-7-hydroxy-2H-1,2,4-benzothiadiazine 1,1-dioxide | n/a | |
| 7 | P22756_7E5 | 7E5 | n/a | 90480133 | CHEMBL4117901 | (2~{S},4~{R})-4-(2-carboxyphenoxy)pyrrolidine-2-carboxylic acid | n/a | |
| 8 | P22756_7M6 | 7M6 | n/a | 11161396 | CHEMBL581906 | 7-chloro-4-(2-fluoroethyl)-2,3-dihydro-1,2,4-benzothiadiazine 1,1-dioxide | n/a | |
| 9 | P22756_8VE | 8VE | n/a | 24850532 | n/a | (3~{a}~{R},4~{S},6~{a}~{R})-1-methyl-4,5,6,6~{a}-tetrahydro-3~{a}~{H}-pyrrolo[3,4-c]pyrazole-3,4-dicarboxylic acid | n/a | |
| 10 | P22756_8VN | 8VN | n/a | 10262175 | CHEMBL125440 | (3~{a}~{S},4~{S},6~{a}~{R})-4,5,6,6~{a}-tetrahydro-3~{a}~{H}-pyrrolo[3,4-d][1,2]oxazole-3,4-dicarboxylic acid | n/a | |
| 11 | P22756_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 12 | P22756_AT1 | AT1 | DB02347 | 447249 | CHEMBL594840 | (S)-2-AMINO-3-(5-TERT-BUTYL-3-(PHOSPHONOMETHOXY)-4-ISOXAZOLYL)PROPIONIC ACID | n/a | Ki(nM) = 2900.0 |
| 13 | P22756_BR | BR | n/a | 259 | n/a | BROMIDE ION | n/a | |
| 14 | P22756_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 15 | P22756_CS | CS | n/a | 104967 | n/a | CESIUM ION | n/a | |
| 16 | P22756_DOQ | DOQ | DB02852 | 5282253 | CHEMBL1232313 | (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID | n/a | |
| 17 | P22756_DYH | DYH | n/a | 9839436;15450383; | CHEMBL221142 | (2R,3aR,6S,7R,7aR)-2-[(2S)-2-amino-2-carboxyethyl]-6-hydroxy-7-(methylamino)hexahydro-2H-furo[3,2-b]pyran-2-carboxylic acid | n/a | |
| 18 | P22756_EC8 | EC8 | n/a | 137319634 | CHEMBL5193862 | N-(7-fluoro-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)-2-hydroxybenzamide | n/a | |
| 19 | P22756_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 20 | P22756_GLU | GLU | DB00142 | 33032;44272391;88747398; | CHEMBL575060 | GLUTAMIC ACID | n/a | Ki(nM) = 140.0 EC50(nM) = 35200.0 |
| 21 | P22756_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 22 | P22756_IBC | IBC | DB04152 | 5288598 | CHEMBL28472 | 3-(3-HYDROXY-7,8-DIHYDRO-6H-CYCLOHEPTA[D]ISOXAZOL-4-YL)-L-ALANINE | n/a | Ki(nM) = 2.57 EC50(nM) = 130.0 |
| 23 | P22756_K | K | n/a | 813 | CHEMBL1233793 | POTASSIUM ION | n/a | |
| 24 | P22756_KAI | KAI | n/a | 10255;44338126; | CHEMBL275040 | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE | n/a | |
| 25 | P22756_L5H | L5H | n/a | 139582018 | n/a | ~{N}-[7-imidazol-1-yl-2,3-bis(oxidanylidene)-6-(trifluoromethyl)-4~{H}-quinoxalin-1-yl]benzamide | n/a | |
| 26 | P22756_LI | LI | n/a | 28486 | CHEMBL1234004 | LITHIUM ION | n/a | |
| 27 | P22756_LY5 | LY5 | n/a | 9935648 | CHEMBL1234118 | (3S,4aR,6S,8aR)-6-{[(2S)-2-carboxy-4,4-difluoropyrrolidin-1-yl]methyl}decahydroisoquinoline-3-carboxylic acid | n/a | |
| 28 | P22756_MS8 | MS8 | n/a | 10658919 | n/a | (2R,3aR,7aR)-2-[(2S)-2-amino-3-hydroxy-3-oxo-propyl]-3,3a,5,6,7,7a-hexahydrofuro[4,5-b]pyran-2-carboxylic acid | n/a | |
| 29 | P22756_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 30 | P22756_NH4 | NH4 | n/a | 223;16741146; | n/a | AMMONIUM ION | n/a | |
| 31 | P22756_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 32 | P22756_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 33 | P22756_RB | RB | n/a | 105153 | n/a | RUBIDIUM ION | n/a | |
| 34 | P22756_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 35 | P22756_TZG | TZG | n/a | 53393826 | CHEMBL1835337 | (S)-2-amino-3-(2-(2-carboxyethyl)-5-chloro-4-nitrophenyl)propionic acid | n/a | |
| 36 | P22756_UB1 | UB1 | n/a | 16124969 | CHEMBL220822 | 3-({3-[(2S)-2-amino-2-carboxyethyl]-5-methyl-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}methyl)-4,5-dibromothiophene-2-carboxylic acid | n/a | |
| 37 | P22756_UBA | UBA | n/a | 6420160 | CHEMBL373428 | (S)-1-(2-AMINO-2-CARBOXYETHYL)-3(2-CARBOXYTHIOPHENE-3-YL-METHYL)-5-METHYLPYRIMIDINE-2,4-DIONE | n/a | |
| 38 | P22756_UBC | UBC | n/a | 6420161 | CHEMBL372797 | (S)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE | n/a | |
| 39 | P22756_UBE | UBE | n/a | 16125102 | CHEMBL373429 | 3-({3-[(2S)-2-amino-2-carboxyethyl]-5-methyl-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}methyl)-5-phenylthiophene-2-carboxylic acid | n/a | |
| 40 | P22756_UBF | UBF | n/a | 16124964 | CHEMBL221321 | 3-({3-[(2S)-2-amino-2-carboxyethyl]-5-bromo-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}methyl)thiophene-2-carboxylic acid | n/a |