P22906 DYR_CANAX
Gene name: DFR1
Protein name: Dihydrofolate reductase (EC

List of molecules and drugs that interact with protein P22906

#	DrugDomain Data	PBD ligand	DrugBank Accession	PubChem	ChEMBL	Name	Drug action	Affinity data
1	P22906_18G	18G	n/a	73254835	n/a	5-[3-(2,5-dimethoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine	n/a
2	P22906_18H	18H	n/a	73254836	n/a	5-[3-(2-methoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine	n/a
3	P22906_CLZ	CLZ	DB01929	152217	CHEMBL6708	5-CHLORYL-2,4,6-QUINAZOLINETRIAMINE	n/a
4	P22906_GLY	GLY	DB00145	750;5257127;	CHEMBL773	GLYCINE	n/a
5	P22906_GOL	GOL	DB09462	753	CHEMBL692	GLYCEROL	n/a
6	P22906_GW3	GW3	DB07862	1881	CHEMBL318721	7-(1-ETHYL-PROPYL)-7H-PYRROLO-[3,2-F]QUINAZOLINE-1,3-DIAMINE	n/a	Ki(nM) = 0.22 IC50(nM) = 4.0
7	P22906_MES	MES	DB03814	78165;4478249;	CHEMBL1234276	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	n/a
8	P22906_MQ1	MQ1	DB02402	447098	n/a	5-(4-METHOXYPHENOXY)-2,4-QUINAZOLINEDIAMINE	n/a
9	P22906_MQU	MQU	DB08203	447099	n/a	7-[2-METHOXY-1-(METHOXYMETHYL)ETHYL]-7H-PYRROLO[3,2-F] QUINAZOLINE-1,3-DIAMINE	n/a
10	P22906_NDP	NDP	DB02338	5884;134821689;	CHEMBL407009	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	n/a
11	P22906_PO4	PO4	DB14523	1061	n/a	PHOSPHATE ION	n/a
12	P22906_TQ3	TQ3	DB04163	446244	CHEMBL100239	5-PHENYLSULFANYL-2,4-QUINAZOLINEDIAMINE	n/a	IC50(nM) = 34.0
13	P22906_TQ4	TQ4	DB04306	446245	CHEMBL83547	5-[(4-METHYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE	n/a	IC50(nM) = 23.0
14	P22906_TQ5	TQ5	DB01958	3537	CHEMBL329985	5-[4-TERT-BUTYLPHENYLSULFANYL]-2,4-QUINAZOLINEDIAMINE	n/a	IC50(nM) = 8.0
15	P22906_TQ6	TQ6	DB02001	3534	CHEMBL328827	5-(4-MORPHOLIN-4-YL-PHENYLSULFANYL)-2,4-QUINAZOLINEDIAMINE	n/a	IC50(nM) = 130.0