Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
P23219 PGH1_HUMAN
Gene name: PTGS1
Protein name: Prostaglandin G/H synthase

List of molecules and drugs that interact with protein P23219

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 P23219_FLC FLC n/a 31348 n/a CITRATE ANION n/a
2 P23219_LAX LAX DB00154 5280581 CHEMBL465183 Dihomo-gamma-linolenic acid inhibitor
3 P23219_EPA EPA DB00159 446284 CHEMBL460026 Icosapent inhibitor
4 P23219_DB00244 n/a DB00244 n/a n/a Mesalazine inhibitor
5 P23219_TYL TYL DB00316 1983 CHEMBL112 Acetaminophen inhibitor Ki(nM) = 10000.0
IC50(nM) = 200000.0
6 P23219_IMN IMN DB00328 3715 CHEMBL6 Indomethacin inhibitor Ki(nM) = 13.0
IC50(nM) = 0.14
Kd(nM) = 253.0
7 P23219_MXD MXD DB00350 n/a CHEMBL802 Minoxidil inducer
8 P23219_NBO NBO DB00461 4409 CHEMBL1070 Nabumetone inhibitor Ki(nM) = 10000.0
9 P23219_DB00465 n/a DB00465 n/a n/a Ketorolac inhibitor Ki(nM) = 0.19
IC50(nM) = 1230.0
10 P23219_DB00469 n/a DB00469 n/a n/a Tenoxicam inhibitor
11 P23219_TLT TLT DB00500 5509 CHEMBL1020 Tolmetin inhibitor Ki(nM) = 350.0
IC50(nM) = 350.0
12 P23219_DB00554 n/a DB00554 n/a n/a Piroxicam inhibitor Ki(nM) = 760.0
IC50(nM) = 1300.0
13 P23219_DB00573 n/a DB00573 n/a n/a Fenoprofen inhibitor Ki(nM) = 2730.0
14 P23219_DIF DIF DB00586 3033 CHEMBL139 Diclofenac inhibitor IC50(nM) = 3.0
15 P23219_DB00605 n/a DB00605 n/a n/a Sulindac inhibitor
16 P23219_DB00711 n/a DB00711 n/a n/a Diethylcarbamazine inhibitor
17 P23219_DB00712 n/a DB00712 n/a n/a Flurbiprofen inhibitor Ki(nM) = 75.0
IC50(nM) = 10.0
18 P23219_DB00749 n/a DB00749 n/a n/a Etodolac inhibitor Ki(nM) = 1200.0
IC50(nM) = 9.4
19 P23219_ID8 ID8 DB00784 4044 CHEMBL686 Mefenamic acid inhibitor Ki(nM) = 1940.0
IC50(nM) = 25000.0
20 P23219_NPS NPS DB00788 156391 CHEMBL154 Naproxen inhibitor IC50(nM) = 8650.0
21 P23219_SAS SAS DB00795 n/a CHEMBL421 Sulfasalazine inhibitor
22 P23219_P1Z P1Z DB00812 4781 CHEMBL101 Phenylbutazone inhibitor
23 P23219_MXM MXM DB00814 54677470 CHEMBL599 Meloxicam inhibitor Ki(nM) = 140.0
IC50(nM) = 37.0
24 P23219_DB00821 n/a DB00821 n/a n/a Carprofen inhibitor Ki(nM) = 87.0
IC50(nM) = 5.3
25 P23219_1FL 1FL DB00861 3059 CHEMBL898 Diflunisal inhibitor Ki(nM) = 10000.0
26 P23219_DB00870 n/a DB00870 n/a n/a Suprofen inhibitor Ki(nM) = 1100.0
IC50(nM) = 560.0
27 P23219_SAL SAL DB00936 338;118212070; CHEMBL424 Salicylic acid inhibitor Ki(nM) = 10000.0
IC50(nM) = 40000.0
28 P23219_JMS JMS DB00939 4037 CHEMBL509 Meclofenamic acid inhibitor Ki(nM) = 220.0
IC50(nM) = 220.0
29 P23219_AIN AIN DB00945 2244 CHEMBL25 Acetylsalicylic acid inhibitor Ki(nM) = 1700.0
IC50(nM) = 350.0
30 P23219_27R 27R DB00963 60726 CHEMBL1077 Bromfenac inhibitor
31 P23219_BJ6 BJ6 DB00991 4614;52326892; CHEMBL1071 Oxaprozin inhibitor Ki(nM) = 10000.0
IC50(nM) = 740.0
32 P23219_DB01009 n/a DB01009 n/a n/a Ketoprofen inhibitor Ki(nM) = 47.0
IC50(nM) = 2.0
33 P23219_DB01014 n/a DB01014 n/a n/a Balsalazide inhibitor
34 P23219_DB01050 n/a DB01050 n/a n/a Ibuprofen inhibitor Ki(nM) = 48.0
IC50(nM) = 290.0
35 P23219_LUR LUR DB01283 151166 CHEMBL404108 Lumiracoxib inhibitor IC50(nM) = 7.0
36 P23219_DB01397 n/a DB01397 n/a n/a Magnesium salicylate inhibitor
37 P23219_DB01399 n/a DB01399 n/a n/a Salsalate inhibitor Ki(nM) = 10000.0
38 P23219_DB01401 n/a DB01401 n/a n/a Choline magnesium trisalicylate inhibitor Ki(nM) = 10000.0
39 P23219_DB01419 n/a DB01419 n/a n/a Antrafenine inhibitor
40 P23219_DB01435 n/a DB01435 n/a n/a Antipyrine inhibitor
41 P23219_DB01600 n/a DB01600 n/a n/a Tiaprofenic acid inhibitor
42 P23219_OAS OAS DB01837 99478;6971051; CHEMBL1234916 O-acetyl-L-serine inhibitor
43 P23219_DB01892 n/a DB01892 n/a n/a Hyperforin inhibitor
44 P23219_BFL BFL DB02047 448006 n/a (+)-2-(4-biphenyl)propionic acid inhibitor
45 P23219_DB02110 n/a DB02110 n/a n/a Protoporphyrin Ix Containing Co n/a
46 P23219_BXA BXA DB02198 6227 CHEMBL60851 2-Bromoacetyl Group inhibitor
47 P23219_FLF FLF DB02266 3371 CHEMBL23588 Flufenamic acid inhibitor IC50(nM) = 2230.0
48 P23219_BGC BGC DB02379 64689 CHEMBL1614854 Beta-D-Glucose inhibitor
49 P23219_STL STL DB02709 445154 CHEMBL165 Resveratrol inhibitor Ki(nM) = 10000.0
IC50(nM) = 380.0
50 P23219_34C 34C DB02773 2084 n/a (3-Chloro-4-Propoxy-Phenyl)-Acetic Acid inhibitor
51 P23219_SCL SCL DB03667 445302 n/a Acetic Acid Salicyloyl-Amino-Ester inhibitor
52 P23219_ISF ISF DB03752 447834 n/a P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid inhibitor
53 P23219_FL2 FL2 DB03753 446134 n/a Flurbiprofen Methyl Ester n/a
54 P23219_N4E N4E DB03783 4754 CHEMBL16073 Phenacetin inhibitor
55 P23219_NFL NFL DB04552 4488 CHEMBL63323 Niflumic acid n/a Ki(nM) = 10000.0
56 P23219_ACD ACD DB04557 444899 CHEMBL15594 Arachidonic Acid inhibitor
57 P23219_DB04817 n/a DB04817 n/a n/a Metamizole inhibitor
58 P23219_DB06725 n/a DB06725 n/a n/a Lornoxicam inhibitor
59 P23219_DB06736 n/a DB06736 n/a n/a Aceclofenac inhibitor
60 P23219_DB06802 n/a DB06802 n/a n/a Nepafenac inhibitor
61 P23219_IM8 IM8 DB07981 16741227 CHEMBL24957 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1R)-1-(hydroxymethyl)propyl]acetamide n/a
62 P23219_IMM IMM DB07983 447835 CHEMBL590284 1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID inhibitor
63 P23219_IMS IMS DB07984 16741228 CHEMBL27784 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide n/a
64 P23219_DB08814 n/a DB08814 n/a n/a Triflusal antagonist
65 P23219_P0T P0T DB09061 644019 CHEMBL190461 Cannabidiol inhibitor
66 P23219_DB09212 n/a DB09212 n/a n/a Loxoprofen antagonist IC50(nM) = 6500.0
67 P23219_IBP IBP DB09213 39912 CHEMBL175 Dexibuprofen inhibitor IC50(nM) = 99.0
68 P23219_9KL 9KL DB09214 667550 CHEMBL75435 Dexketoprofen antagonist IC50(nM) = 1.9
69 P23219_DB09215 n/a DB09215 n/a n/a Droxicam inhibitor
70 P23219_TLF TLF DB09216 610479 CHEMBL121626 Tolfenamic acid antagonist
71 P23219_DB09288 n/a DB09288 n/a n/a Propacetamol antagonist
72 P23219_DB09295 n/a DB09295 n/a n/a Talniflumate antagonist
73 P23219_DB11071 n/a DB11071 n/a n/a Phenyl salicylate inhibitor
74 P23219_DB11079 n/a DB11079 n/a n/a Trolamine salicylate inhibitor
75 P23219_DB11201 n/a DB11201 n/a n/a Menthyl salicylate antagonist
76 P23219_DB11323 n/a DB11323 n/a n/a Glycol salicylate antagonist
77 P23219_DB12445 n/a DB12445 n/a n/a Nitroaspirin inhibitor
78 P23219_A4Z A4Z DB13346 2466 CHEMBL94394 Bufexamac inhibitor
79 P23219_DB13501 n/a DB13501 n/a n/a Bendazac n/a
80 P23219_DB13783 n/a DB13783 n/a n/a Acemetacin antagonist
81 P23219_DB14011 n/a DB14011 n/a n/a Nabiximols inhibitor