Gene name: RRM1
Protein name: Ribonucleoside-diphosphate reductase large
List of molecules and drugs that interact with protein P23921
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P23921_3X4 | 3X4 | n/a | 92044059 | n/a | N~6~-{N-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl]-2-methyl-D-alanyl}-D-lysine | n/a | |
| 2 | P23921_7LL | 7LL | n/a | 135837470 | n/a | 2-hydroxy-N'-[(Z)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide | n/a | |
| 3 | P23921_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 4 | P23921_ATP | ATP | DB00171 | 5957 | CHEMBL14249 | ADENOSINE-5'-TRIPHOSPHATE | n/a | |
| 5 | P23921_CDP | CDP | DB04555 | 6132 | CHEMBL425252 | CYTIDINE-5'-DIPHOSPHATE | n/a | |
| 6 | P23921_DTP | DTP | DB03222 | 15993 | CHEMBL335538 | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | n/a | |
| 7 | P23921_E4X | E4X | n/a | 132203645 | n/a | 4-bromo-N-((1S,2R)-2-(naphthalen-1-yl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)benzenesulfonamide | n/a | |
| 8 | P23921_E6O | E6O | n/a | 154815510 | n/a | 5-chloro-2-(N-((1S,2R)-2-(2,3-dihydro-1H-inden-4-yl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)sulfamoyl)benzamide | n/a | |
| 9 | P23921_EJ6 | EJ6 | n/a | 138520582 | n/a | 5-chloro-N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)-4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-sulfonamide | n/a | |
| 10 | P23921_GDP | GDP | DB04315 | 8977;5280316;135398619; | CHEMBL384759 | GUANOSINE-5'-DIPHOSPHATE | n/a | |
| 11 | P23921_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 12 | P23921_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 13 | P23921_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 14 | P23921_TTP | TTP | DB02452 | 64968 | CHEMBL363559 | THYMIDINE-5'-TRIPHOSPHATE | n/a | |
| 15 | P23921_CL9 | CL9 | DB00242 | 20279 | CHEMBL1619 | Cladribine | inhibitor | |
| 16 | P23921_GEO | GEO | DB00441 | 60750 | CHEMBL888 | Gemcitabine | inhibitor | |
| 17 | P23921_CFB | CFB | DB00631 | 119182 | CHEMBL1750 | Clofarabine | inhibitor | |
| 18 | P23921_NHY | NHY | DB01005 | 3657 | CHEMBL467 | Hydroxyurea | inhibitor | IC50(nM) = 148000.0 |
| 19 | P23921_DB01073 | n/a | DB01073 | n/a | n/a | Fludarabine | inhibitor | |
| 20 | P23921_DB05003 | n/a | DB05003 | n/a | n/a | Imexon | n/a | |
| 21 | P23921_DB05420 | n/a | DB05420 | n/a | n/a | Gallium maltolate | n/a | |
| 22 | P23921_DB06433 | n/a | DB06433 | n/a | n/a | Tezacitabine | n/a |