P25103 NK1R_HUMAN
Gene name: TACR1
Protein name: Substance-P receptor (SPR)

List of molecules and drugs that interact with protein P25103

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 P25103_CIT CIT DB04272 311;19782904;88113319; CHEMBL1261 CITRIC ACID n/a
2 P25103_CLR CLR DB04540 5997 CHEMBL112570 CHOLESTEROL n/a
3 P25103_GAW GAW DB09048 6451149 CHEMBL206253 2-[3,5-bis(trifluoromethyl)phenyl]-~{N},2-dimethyl-~{N}-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl]propanamide antagonist Ki(nM) = 0.95
IC50(nM) = 0.95
4 P25103_GBK GBK n/a 5311057 CHEMBL441225 (2~{S},3~{S})-~{N}-[(2-methoxyphenyl)methyl]-2-phenyl-piperidin-3-amine n/a
5 P25103_GBQ GBQ DB00673 6918365;135413536; CHEMBL1471 5-[[(2~{R},3~{S})-2-[(1~{R})-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one antagonist Ki(nM) = 0.0794
IC50(nM) = 0.09
6 P25103_L76 L76 n/a 9809077 CHEMBL4303434 1-(4-{[(2R,3S)-2-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholin-4-yl]methyl}-1H-1,2,3-triazol-5-yl)-N,N-dimethylmethanamine n/a
7 P25103_OLA OLA n/a 445639 CHEMBL8659 OLEIC ACID n/a
8 P25103_OLC OLC n/a 11451146 n/a (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate n/a
9 P25103_PEG PEG n/a 8117 CHEMBL1235226 DI(HYDROXYETHYL)ETHER n/a
10 P25103_DB00193 n/a DB00193 n/a n/a Tramadol inhibitor
11 P25103_DB01221 n/a DB01221 n/a n/a Ketamine antagonist
12 P25103_DB04894 n/a DB04894 n/a n/a Vapreotide antagonist
13 P25103_DB05421 n/a DB05421 n/a n/a CP-122721 antagonist
14 P25103_DB05790 n/a DB05790 n/a n/a SR 140333 n/a
15 P25103_DB06634 n/a DB06634 n/a n/a Casopitant antagonist
16 P25103_DB09291 n/a DB09291 n/a n/a Rolapitant antagonist
17 P25103_DB11949 n/a DB11949 n/a n/a Vestipitant antagonist
18 P25103_DB12436 n/a DB12436 n/a n/a Vofopitant n/a
19 P25103_DB14019 n/a DB14019 n/a n/a Fosnetupitant antagonist