Gene name: TACR1
Protein name: Substance-P receptor (SPR)
List of molecules and drugs that interact with protein P25103
# | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
---|---|---|---|---|---|---|---|---|
1 | P25103_CIT | CIT | DB04272 | 311;19782904;88113319; | CHEMBL1261 | CITRIC ACID | n/a | |
2 | P25103_CLR | CLR | DB04540 | 5997 | CHEMBL112570 | CHOLESTEROL | n/a | |
3 | P25103_GAW | GAW | DB09048 | 6451149 | CHEMBL206253 | 2-[3,5-bis(trifluoromethyl)phenyl]-~{N},2-dimethyl-~{N}-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl]propanamide | antagonist | Ki(nM) = 0.95 IC50(nM) = 0.95 |
4 | P25103_GBK | GBK | n/a | 5311057 | CHEMBL441225 | (2~{S},3~{S})-~{N}-[(2-methoxyphenyl)methyl]-2-phenyl-piperidin-3-amine | n/a | |
5 | P25103_GBQ | GBQ | DB00673 | 6918365;135413536; | CHEMBL1471 | 5-[[(2~{R},3~{S})-2-[(1~{R})-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one | antagonist | Ki(nM) = 0.0794 IC50(nM) = 0.09 |
6 | P25103_L76 | L76 | n/a | 9809077 | CHEMBL4303434 | 1-(4-{[(2R,3S)-2-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholin-4-yl]methyl}-1H-1,2,3-triazol-5-yl)-N,N-dimethylmethanamine | n/a | |
7 | P25103_OLA | OLA | n/a | 445639 | CHEMBL8659 | OLEIC ACID | n/a | |
8 | P25103_OLC | OLC | n/a | 11451146 | n/a | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | n/a | |
9 | P25103_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
10 | P25103_DB00193 | n/a | DB00193 | n/a | n/a | Tramadol | inhibitor | |
11 | P25103_DB01221 | n/a | DB01221 | n/a | n/a | Ketamine | antagonist | |
12 | P25103_DB04894 | n/a | DB04894 | n/a | n/a | Vapreotide | antagonist | |
13 | P25103_DB05421 | n/a | DB05421 | n/a | n/a | CP-122721 | antagonist | |
14 | P25103_DB05790 | n/a | DB05790 | n/a | n/a | SR 140333 | n/a | |
15 | P25103_DB06634 | n/a | DB06634 | n/a | n/a | Casopitant | antagonist | |
16 | P25103_DB09291 | n/a | DB09291 | n/a | n/a | Rolapitant | antagonist | |
17 | P25103_DB11949 | n/a | DB11949 | n/a | n/a | Vestipitant | antagonist | |
18 | P25103_DB12436 | n/a | DB12436 | n/a | n/a | Vofopitant | n/a | |
19 | P25103_DB14019 | n/a | DB14019 | n/a | n/a | Fosnetupitant | antagonist |