Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
P25321 KAPCA_CRIGR
Gene name: PRKACA
Protein name: cAMP-dependent protein kinase

List of molecules and drugs that interact with protein P25321

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 P25321_152 152 DB02648 10918 CHEMBL1229656 CARNITINE n/a
2 P25321_1LQ 1LQ n/a 84759 CHEMBL266128 quinazolin-4-amine n/a
3 P25321_1SQ 1SQ n/a 73742 CHEMBL62083 ISOQUINOLIN-1-AMINE n/a
4 P25321_3AB 3AB n/a 1645 CHEMBL81977 3-aminobenzamide n/a
5 P25321_3AE 3AE n/a 9966 CHEMBL443234 4-(trifluoromethyl)benzoic acid n/a
6 P25321_463 463 n/a 2760946 n/a N-[3-(aminomethyl)phenyl]acetamide n/a
7 P25321_46L 46L n/a 99209 CHEMBL394288 6-(dimethylamino)pyridine-3-carboxylic acid n/a
8 P25321_46P 46P n/a 16227799 n/a 4-methyl-5-(1-methyl-1H-imidazol-2-yl)-1,3-thiazol-2-amine n/a
9 P25321_47V 47V n/a 17248960 CHEMBL2357735 2,5-dimethyl-N-(pyridin-4-yl)furan-3-carboxamide n/a
10 P25321_489 489 n/a 38989029 n/a (1S)-2-amino-1-(4-fluorophenyl)ethanol n/a
11 P25321_4NB 4NB n/a 6108 CHEMBL101263 4-NITROBENZOIC ACID n/a
12 P25321_5AO 5AO n/a 2739289 CHEMBL3262562 3-(1,3-oxazol-5-yl)aniline n/a
13 P25321_5H1 5H1 n/a 16054 CHEMBL404923 1H-indol-5-ol n/a
14 P25321_6TV 6TV n/a 14416534 CHEMBL343437 ~{N}-[2-(propylamino)ethyl]isoquinoline-5-sulfonamide n/a
15 P25321_6TX 6TX n/a 137348524 n/a 2-[isoquinolin-5-ylsulfonyl(propyl)amino]ethylazanium n/a
16 P25321_6TY 6TY n/a 6603863 CHEMBL1318551 5-[(2~{R})-2-methylpiperazin-1-yl]sulfonylisoquinoline n/a
17 P25321_7CB 7CB n/a 9837177 CHEMBL376726 isoquinoline-5-sulfonamide n/a
18 P25321_7CT 7CT n/a 13135510 n/a ~{N}-methylisoquinoline-5-sulfonamide n/a
19 P25321_7K7 7K7 n/a 137348629 n/a 5-[[(2~{R})-2-methyl-1,4-diazepan-4-ium-1-yl]sulfonyl]isoquinoline n/a
20 P25321_7KB 7KB n/a 9951687 n/a 5-(1,4-diazepan-1-ylsulfonyl)-4-methyl-isoquinoline n/a
21 P25321_7N9 7N9 n/a 40424706 n/a (5-chloranyl-2-methoxy-phenyl)methylazanium n/a
22 P25321_7QF 7QF n/a 164890082 n/a 2-azanyl-5-[3-[(2R)-morpholin-2-yl]phenyl]benzenecarbonitrile n/a
23 P25321_7QI 7QI n/a 164890081 n/a 2-azanyl-5-[3-[(3R)-morpholin-3-yl]phenyl]benzenecarbonitrile n/a
24 P25321_7QL 7QL n/a 164890083 CHEMBL5278563 5-[3-[4-(aminomethyl)oxan-4-yl]phenyl]-2-azanyl-benzenecarbonitrile n/a
25 P25321_7QR 7QR n/a 164890084 CHEMBL5266306 6-azanyl-2-chloranyl-3-[(Z)-piperidin-3-ylidenemethyl]benzenecarbonitrile n/a
26 P25321_7QW 7QW n/a 164890085 CHEMBL5280643 6-[3-[[(3~{R})-3-azanylpyrrolidin-1-yl]methyl]phenyl]-4~{H}-isoquinolin-1-one n/a
27 P25321_7W8 7W8 n/a 155969802 CHEMBL5279025 2-azanyl-6-[5-[(dimethylamino)methyl]-2-fluoranyl-phenyl]-1H-indole-3-carbonitrile n/a
28 P25321_8ET 8ET n/a 952495 CHEMBL1343177 ~{N}-quinolin-5-ylpyridine-3-carboxamide n/a
29 P25321_8FZ 8FZ n/a 82504648 n/a (5-pyridin-3-yloxyfuran-2-yl)methanamine n/a
30 P25321_8G2 8G2 n/a 8465110 n/a (4-methoxycarbonylphenyl)methylazanium n/a
31 P25321_8G5 8G5 n/a 800171 n/a (4R)-4-(2-amino-1,3-thiazol-4-yl)-1-oxaspiro[4.5]decan-2-one n/a
32 P25321_8G8 8G8 n/a 7147173 n/a 2-chloranyl-9-methyl-purine n/a
33 P25321_8GB 8GB n/a 2384321 n/a 1-[5-chloranyl-3-(chloromethyl)-2-oxidanyl-phenyl]ethanone n/a
34 P25321_8JT 8JT n/a 4745321 n/a 1,3-benzodioxol-5-ylmethyl(cyclopentyl)azanium n/a
35 P25321_8JW 8JW n/a 2315787 n/a 3-azanyl-5-(trifluoromethyl)-1~{H}-pyridin-2-one n/a
36 P25321_8K2 8K2 n/a 1241301 CHEMBL447118 5-chloranylthiophene-2-sulfonamide n/a
37 P25321_8K5 8K5 n/a 4613900 n/a [azanyl-[(4-chlorophenyl)methylsulfanyl]methylidene]azanium n/a
38 P25321_8KB 8KB n/a 55298904 n/a (6~{R})-1,4-oxazepan-6-ol n/a
39 P25321_8LZ 8LZ n/a 2529563 n/a (2~{S})-2-(2,3-dihydro-1,4-benzodioxin-6-yl)pyrrolidin-1-ium n/a
40 P25321_8M2 8M2 n/a 6932604 n/a [azanyl(thiophen-3-yl)methylidene]azanium n/a
41 P25321_8NE 8NE n/a 6339126 n/a [azanyl-[4-(trifluoromethyl)phenyl]methylidene]azanium n/a
42 P25321_8PQ 8PQ n/a 76937 n/a 4-bromanyl-3,5-dimethyl-1~{H}-pyrazole n/a
43 P25321_9K6 9K6 n/a 42610506 n/a 5-[[(2~{S})-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline n/a
44 P25321_9LQ 9LQ n/a 134159758 n/a [2-[(4-isoquinolin-5-ylsulfonyl-1,4-diazepan-1-yl)methyl]phenyl]boronic acid n/a
45 P25321_9NT 9NT n/a 4600840 n/a ~{N}-(1,3-benzodioxol-5-yl)-2-piperidin-1-ium-1-yl-ethanamide n/a
46 P25321_ADE ADE DB00173 190 CHEMBL226345 ADENINE n/a
47 P25321_ADP ADP DB16833 6022 CHEMBL14830 ADENOSINE-5'-DIPHOSPHATE n/a
48 P25321_AMP AMP DB00131 6083 CHEMBL752 ADENOSINE MONOPHOSPHATE n/a
49 P25321_AO8 AO8 n/a 137348934 n/a [2-[[2-(isoquinolin-5-ylsulfonylamino)ethylamino]methyl]phenyl]boronic acid n/a
50 P25321_ATP ATP DB00171 5957 CHEMBL14249 ADENOSINE-5'-TRIPHOSPHATE n/a
51 P25321_B4Z B4Z n/a 15296927 CHEMBL148132 ~{N}-[2-[(phenylmethyl)amino]ethyl]isoquinoline-5-sulfonamide n/a
52 P25321_BEZ BEZ DB03793 243;20144841; CHEMBL541 BENZOIC ACID n/a
53 P25321_BJK BJK n/a 6969855;153274104; n/a (4-methoxy-3-oxidanyl-phenyl)methylazanium n/a
54 P25321_BJN BJN n/a 6951177;153274102; n/a 2-pyridin-3-ylethylazanium n/a
55 P25321_BJQ BJQ n/a 8022405 n/a [(2~{S})-1-methoxy-1-oxidanylidene-3-phenyl-propan-2-yl]azanium n/a
56 P25321_BVZ BVZ n/a 134822017 n/a [2-[(4-isoquinolin-5-ylsulfonyl-1,4-diazepan-1-yl)methyl]phenyl]-tris(oxidanyl)boranuide n/a
57 P25321_CDT CDT DB03364 448878 n/a 4-METHYLSULFANYL-2-UREIDO-BUTYRIC ACID n/a
58 P25321_CL CL n/a 312 n/a CHLORIDE ION n/a
59 P25321_DAR DAR DB04027 1549104;17753939;58433835;59667378; n/a D-ARGININE n/a
60 P25321_DMS DMS DB01093 679 CHEMBL504 DIMETHYL SULFOXIDE n/a
61 P25321_E5E E5E n/a 6921840 n/a Noradrenaline n/a
62 P25321_E9Q E9Q n/a 4962701 CHEMBL2393369 5-azanyl-3-pyrrolidin-1-yl-1~{H}-pyrazole-4-carbonitrile n/a
63 P25321_F05 F05 n/a 427859 CHEMBL1617729 1H-isoindol-3-amine n/a
64 P25321_GAB GAB DB02054 7419 CHEMBL307782 3-AMINOBENZOIC ACID n/a
65 P25321_GGB GGB DB01833 439202;46224610; CHEMBL443732 L-CANAVANINE n/a
66 P25321_H52 H52 DB07876 448043 CHEMBL406821 (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE n/a
67 P25321_HBD HBD n/a 65052 CHEMBL123617 4-HYDROXYBENZAMIDE n/a
68 P25321_IPH IPH DB03255 996;20488062; CHEMBL14060 PHENOL n/a
69 P25321_IQP IQP DB07996 449240 CHEMBL1233654 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE n/a
70 P25321_IQU IQU n/a n/a CHEMBL344314 N-(2-AMINOETHYL)ISOQUINOLINE-5-SULFONAMIDE n/a
71 P25321_ISQ ISQ DB04329 8405 CHEMBL12315 ISOQUINOLINE n/a
72 P25321_LQ2 LQ2 n/a 506057 CHEMBL335258 4-aminocarbonylbenzoic acid n/a
73 P25321_LR5 LR5 n/a 74684 CHEMBL4065573 4-(trifluoromethyl)benzamide n/a
74 P25321_LR8 LR8 n/a 260349 CHEMBL1720183 6-morpholin-4-ylpyridine-3-carboxamide n/a
75 P25321_LRT LRT n/a 49870878 CHEMBL1667963 5-(1,4-diazepan-1-ylsulfonyl)isoquinolin-1-amine n/a
76 P25321_M77 M77 DB08162 3547 CHEMBL38380 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE n/a
77 P25321_MG MG n/a 888 n/a MAGNESIUM ION n/a
78 P25321_MOH MOH n/a 887 CHEMBL14688 METHANOL n/a
79 P25321_MPD MPD DB03564 5288834 n/a (4S)-2-METHYL-2,4-PENTANEDIOL n/a
80 P25321_MRD MRD n/a 5288845 n/a (4R)-2-METHYLPENTANE-2,4-DIOL n/a
81 P25321_NCA NCA DB02701 936 CHEMBL1140 NICOTINAMIDE n/a
82 P25321_NPO NPO DB04417 980 CHEMBL14130 P-NITROPHENOL n/a
83 P25321_NTN NTN n/a 409094 n/a ISONICOTINAMIDINE n/a
84 P25321_O72 O72 n/a 2737037 n/a 1,7-naphthyridin-8-amine n/a
85 P25321_OGB OGB n/a 313259 n/a methyl isoquinoline-5-carboxylate n/a
86 P25321_P4Q P4Q n/a 55281763 n/a pyrido[3,2-d]pyrimidin-4-amine n/a
87 P25321_P4W P4W n/a 13135518 n/a ~{N},~{N}-dimethylisoquinoline-5-sulfonamide n/a
88 P25321_P72 P72 n/a 217125 CHEMBL363685 4-oxidanylbenzenecarboximidamide n/a
89 P25321_RIB RIB n/a 445894 CHEMBL606078 alpha-D-ribofuranose n/a
90 P25321_RIP RIP DB04286 441481 CHEMBL1159662 beta-D-ribopyranose n/a
91 P25321_S95 S95 n/a 241599 n/a isoquinoline-5-sulfonic acid n/a
92 P25321_S9B S9B n/a 260936 n/a isoquinoline-5-carboxylic acid n/a
93 P25321_UNU UNU n/a
94 P25321_T7W T7W n/a 162394461 n/a (R)-3,3-dimethyl-5-oxo-5-(6-(3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)-1,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridin-5-yl)pentanoic acid n/a
95 P25321_T82 T82 n/a 162394535 n/a (S,E)-3-(2-(3-bromo-4-hydroxybenzylidene)hydrazineyl)-2-(3-chlorophenyl)-3-oxopropan-1-aminium n/a