Gene name:
Protein name: Cruzipain (EC 3.4.22.51)
List of molecules and drugs that interact with protein P25779
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P25779_0I5 | 0I5 | n/a | 25108695 | CHEMBL5398692 | N-[(3S)-1-fluoro-2-oxo-5-phenylpentan-3-yl]-N~2~-(morpholin-4-ylcarbonyl)-L-leucinamide | n/a | |
| 2 | P25779_186 | 186 | DB01810 | 5287438 | n/a | [1-(1-METHYL-4,5-DIOXO-PENT-2-ENYLCARBAMOYL)-2-PHENYL-ETHYL]-CARBAMIC ACID BENZYL ESTER | n/a | |
| 3 | P25779_1RV | 1RV | n/a | 40701156 | n/a | 2-{[(1H-1,2,4-triazol-5-ylsulfanyl)acetyl]amino}thiophene-3-carboxamide | n/a | |
| 4 | P25779_25B | 25B | n/a | 49866437 | n/a | (1R,2R)-2-[(4-chlorophenyl)carbonyl]-N-{(1S)-1-[2-(phenylsulfonyl)ethyl]pentyl}cyclohexanecarboxamide | n/a | |
| 5 | P25779_2V5 | 2V5 | n/a | 163190806 | n/a | N-[(2S)-5-(carbamimidamidooxy)-1-oxo-1-{[(1E,3S)-5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl]amino}pentan-2-yl]-4-methylpiperazine-1-carboxamide | n/a | |
| 6 | P25779_2VC | 2VC | n/a | 90684386 | CHEMBL3774432 | N-[(2S)-5-(carbamimidamidooxy)-1-oxo-1-{[(1E,3S)-5-phenyl-1-(pyrimidin-2-ylsulfonyl)pent-1-en-3-yl]amino}pentan-2-yl]-4-methylpiperazine-1-carboxamide | n/a | |
| 7 | P25779_33L | 33L | n/a | 137348120 | n/a | N-(2-aminoethyl)-Nalpha-benzoyl-L-phenylalaninamide | n/a | |
| 8 | P25779_3H5 | 3H5 | n/a | 42285820 | n/a | N-(1H-benzimidazol-2-yl)-1,3-dimethyl-1H-pyrazole-4-carboxamide | n/a | |
| 9 | P25779_3H6 | 3H6 | n/a | 17452964 | n/a | N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)-1H-pyrazole-4-carboxamide | n/a | |
| 10 | P25779_3H7 | 3H7 | n/a | 737406 | n/a | 4,6-difluoro-1,3-benzothiazol-2-amine | n/a | |
| 11 | P25779_4MC | 4MC | n/a | 25028695 | CHEMBL1230301 | (Z)-N-(5-GUANIDINO-1-OXO-1-(5-PHENYL-1-(PHENYLSULFONYL)PENT-1-EN-3-YLAMINO)PENTAN-2-YL)-4-METHYLPIPERAZINE-1-CARBOXAMID E | n/a | |
| 12 | P25779_83E | 83E | n/a | 162677681 | n/a | N,N-dimethyl-L-valyl-L-leucyl-N-[(3S)-6-{(2S)-2-[([1,1'-biphenyl]-4-yl)methyl]-3-methoxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl}-6-oxo-1-phenylhexan-3-yl]-L-leucinamide | n/a | |
| 13 | P25779_83K | 83K | n/a | 162677682 | n/a | N,N-dimethyl-L-valyl-L-leucyl-N-[(3S)-6-{(2S)-2-[(1H-indol-3-yl)methyl]-3-methoxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl}-6-oxo-1-phenylhexan-3-yl]-L-leucinamide | n/a | |
| 14 | P25779_B95 | B95 | n/a | 1183113 | CHEMBL1173694 | N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenoxy)acetamide | n/a | |
| 15 | P25779_D1R | D1R | n/a | 52946595 | n/a | NALPHA-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-N-{(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}-L-PHENYLALANINAMIDE | n/a | |
| 16 | P25779_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 17 | P25779_EOH | EOH | DB00898 | 702 | CHEMBL545 | ETHANOL | n/a | |
| 18 | P25779_GN9 | GN9 | n/a | 155542288 | CHEMBL4519895 | gallinamide A, bound form | n/a | |
| 19 | P25779_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 20 | P25779_K | K | n/a | 813 | CHEMBL1233793 | POTASSIUM ION | n/a | |
| 21 | P25779_KB2 | KB2 | n/a | 49867189 | n/a | (3S)-3-(4-{(1S)-1,2-dimethyl-1-[(quinolin-6-ylmethyl)amino]propyl}-1H-1,2,3-triazol-1-yl)heptan-2-one | n/a | |
| 22 | P25779_P10 | P10 | DB02128 | 5289091 | n/a | [1-(3-HYDROXY-2-OXO-1-PHENETHYL-PROPYLCARBAMOYL)2-PHENYL-ETHYL]-CARBAMIC ACID PYRIDIN-4-YLMETHYL ESTER | n/a | |
| 23 | P25779_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 24 | P25779_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 25 | P25779_QL2 | QL2 | n/a | 44143088 | CHEMBL567341 | 6-[(3,5-difluorophenyl)amino]-9-ethyl-9H-purine-2-carbonitrile | n/a | |
| 26 | P25779_R99 | R99 | DB03573 | 5289258 | n/a | N-[3-CARBOXY-2-HYDROXY-PROPIONYL]-D-HOMOPHENYLALANYL-AMINO-2-METHYLBUTANE | inhibitor | |
| 27 | P25779_RL2 | RL2 | DB03691 | 5289294 | n/a | N-[3-CARBOXY-2-HYDROXY-PROPIONYL]-L-HOMOPHENYLALANYL-AMINO-2-METHYLBUTANE | inhibitor | |
| 28 | P25779_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 29 | P25779_TM8 | TM8 | n/a | 155804544 | n/a | Nalpha-[(benzyloxy)carbonyl]-N-[(2S)-1-phenyl-4-(phenylsulfonyl)butan-2-yl]-L-phenylalaninamide | n/a | |
| 30 | P25779_VS1 | VS1 | n/a | 5289559 | n/a | 3-[[N-[MORPHOLIN-N-YL]-CARBONYL]-PHENYLALANINYL-AMINO]-5- PHENYL-PENTANE-1-SULFONYLBENZENE | n/a | |
| 31 | P25779_VS2 | VS2 | DB02200 | 5289560 | n/a | 3-[N-[BENZYLOXYCARBONYL]-PHENYLALANINYL-AMINO]-5-PHENYL-PENTANE-1-SULFONYLMETHYLBENZENE | n/a | |
| 32 | P25779_VS3 | VS3 | DB02051 | 5289561 | n/a | 3-[N-[BENZYLOXYCARBONYL]-PHENYLALANINYL-AMINO]-5-PHENYL-PENTANE-1-SULFONIC ACID 4-NITRO-PHENYL ESTER | n/a | |
| 33 | P25779_VS4 | VS4 | DB04427 | 5289562 | n/a | 3-[[N-[4-METHYL-PIPERAZINYL]CARBONYL]-PHENYLALANINYL-AMINO]-5-PHENYL-PENTANE-1-SULFONIC ACID BENZYLOXY-AMIDE | n/a | |
| 34 | P25779_VSC | VSC | DB04502 | 17754216 | n/a | N-[N'-BENZYLOXYCARBONYL-PHENYLALANINYL]-3-AMINO-5-PHENYL-PENTANE-1-SULFONIC ACID PHENYL ESTER | inhibitor | |
| 35 | P25779_Z22 | Z22 | n/a | 18064 | CHEMBL1236925 | S-methyl methanesulfonothioate | n/a | |
| 36 | P25779_ZRA | ZRA | DB03536 | 131704251 | n/a | BENZOYL-ARGININE-ALANINE-FLUORO-METHYL KETONE | n/a | |
| 37 | P25779_ZYA | ZYA | DB08775 | 15118984 | CHEMBL68828 | BENZOYL-TYROSINE-ALANINE-FLUORO-METHYL KETONE | n/a | |
| 38 | P25779_T10 | T10 | DB01871 | 5289424 | CHEMBL261723 | [1-(1-BENZYL-3-HYDROXY-2-OXO-PROPYLCARBAMOYL)-2-PHENYL-ETHYL]-CARBAMIC ACID BENZYL ESTER | n/a |