Gene name: folK
Protein name: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC
List of molecules and drugs that interact with protein P26281
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P26281_5RU | 5RU | n/a | 861230;135567097; | CHEMBL3359162 | 2-azanyl-8-[(2-fluorophenyl)methylsulfanyl]-1,9-dihydropurin-6-one | n/a | |
| 2 | P26281_5RV | 5RV | n/a | 118988415;135567098; | CHEMBL3818695 | 2-[(2-azanyl-6-oxidanylidene-3,9-dihydropurin-8-yl)sulfanylmethyl]benzenecarbonitrile | n/a | |
| 3 | P26281_5RW | 5RW | n/a | 861229;135522636; | CHEMBL3819104 | 2-azanyl-8-[(4-fluorophenyl)methylsulfanyl]-1,7-dihydropurin-6-one | n/a | |
| 4 | P26281_5RX | 5RX | n/a | 861231;135401802; | CHEMBL276808 | 2-azanyl-8-[(4-chlorophenyl)methylsulfanyl]-1,9-dihydropurin-6-one | n/a | |
| 5 | P26281_5RY | 5RY | n/a | 118988416;135567099; | CHEMBL3819281 | 4-[(2-azanyl-6-oxidanylidene-1,9-dihydropurin-8-yl)sulfanylmethyl]-3-fluoranyl-benzenecarbonitrile | n/a | |
| 6 | P26281_5RZ | 5RZ | n/a | 118988417;135567100; | CHEMBL3818894 | 2-azanyl-8-[2-(4-bromophenyl)-2-oxidanylidene-ethyl]sulfanyl-1,9-dihydropurin-6-one | n/a | |
| 7 | P26281_87Y | 87Y | DB04610 | 4369143;5287557;135509072; | n/a | 7,8-DIHYDRO-6-HYDROXYMETHYL-7-METHYL-7-[2-PHENYLETHYL]-PTERIN | n/a | |
| 8 | P26281_A4P | A4P | DB04158 | 5287583;6323200;135509074; | n/a | 6-(ADENOSINE TETRAPHOSPHATE-METHYL)-7,8-DIHYDROPTERIN | n/a | |
| 9 | P26281_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 10 | P26281_ADP | ADP | DB16833 | 6022 | CHEMBL14830 | ADENOSINE-5'-DIPHOSPHATE | n/a | |
| 11 | P26281_AMP | AMP | DB00131 | 6083 | CHEMBL752 | ADENOSINE MONOPHOSPHATE | n/a | |
| 12 | P26281_APC | APC | DB02596 | 91557 | CHEMBL132722 | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | n/a | |
| 13 | P26281_ATP | ATP | DB00171 | 5957 | CHEMBL14249 | ADENOSINE-5'-TRIPHOSPHATE | n/a | |
| 14 | P26281_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 15 | P26281_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 16 | P26281_DX4 | DX4 | DB00352 | 1537;2723601; | CHEMBL727 | 2-amino-1,9-dihydro-6H-purine-6-thione | n/a | |
| 17 | P26281_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 18 | P26281_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 19 | P26281_H73 | H73 | n/a | 139368631 | CHEMBL4783114 | 5'-S-[(2R,4R)-1-{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}-2-carboxypiperidin-4-yl]-5'-thioadenosine | n/a | |
| 20 | P26281_HH2 | HH2 | DB04047 | 151434;5288551;135440058; | n/a | 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE | n/a | |
| 21 | P26281_HHR | HHR | DB03197 | 69736;5288552;135415975; | CHEMBL101541 | 6-HYDROXYMETHYLPTERIN | n/a | |
| 22 | P26281_HHS | HHS | n/a | 70361;5320887;135403803; | CHEMBL566727 | 6-CARBOXYPTERIN | n/a | |
| 23 | P26281_J1A | J1A | n/a | 54754552;135566603; | CHEMBL1928284 | 5'-S-[1-(2-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}ethyl)piperidin-4-yl]-5'-thioadenosine | n/a | |
| 24 | P26281_J1B | J1B | n/a | 137349567 | n/a | 5'-S-[1-(2-{[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}ethyl)piperidin-4-yl]-5'-thioadenosine | n/a | |
| 25 | P26281_J1C | J1C | n/a | 56840246;136058510; | CHEMBL1928285 | 5'-S-[1-(2-{[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)carbonyl]amino}ethyl)piperidin-4-yl]-5'-thioadenosine | n/a | |
| 26 | P26281_J1D | J1D | n/a | 70688299;136266900; | CHEMBL2046607 | 5'-{[2-({N-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)carbonyl]glycyl}amino)ethyl]sulfonyl}-5'-deoxyadenosine | n/a | |
| 27 | P26281_J1F | J1F | n/a | 134812631;135567393; | n/a | ((2-(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carboxamido)-N-(2-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)amino)-2-oxoethyl)acetamido)methyl)phosphonic acid | n/a | |
| 28 | P26281_J1I | J1I | n/a | 137349568 | n/a | 5'-S-{2-[{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}(phosphonomethyl)amino]ethyl}-5'-thioadenosine | n/a | |
| 29 | P26281_J1L | J1L | n/a | 155289406 | CHEMBL4780649 | 5'-{[(2R,4R)-1-{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}-2-carboxypiperidin-4-yl]sulfonyl}-5'-deoxyadenosine | n/a | |
| 30 | P26281_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 31 | P26281_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 32 | P26281_PE0 | PE0 | n/a | 73000;5280368;135398660; | CHEMBL278009 | PTERINE | n/a | |
| 33 | P26281_PH2 | PH2 | DB02119 | 218;5280425;135398568; | CHEMBL1233322 | 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE | n/a | |
| 34 | P26281_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 35 | P26281_TRS | TRS | DB03754 | 3777159;88088752;152743085; | n/a | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 36 | P26281_YH1 | YH1 | n/a | 861221;135526726; | CHEMBL3233201 | 2-amino-8-[(2-oxo-2-phenylethyl)sulfanyl]-1,9-dihydro-6H-purin-6-one | n/a | |
| 37 | P26281_YH2 | YH2 | n/a | 861232;135468747; | CHEMBL3233202 | 4-{[(2-amino-6-oxo-6,9-dihydro-1H-purin-8-yl)sulfanyl]methyl}benzonitrile | n/a | |
| 38 | P26281_YH3 | YH3 | n/a | 73386656;135566867; | CHEMBL3233208 | 2-amino-8-{[2-(3-methylphenyl)-2-oxoethyl]sulfanyl}-1,9-dihydro-6H-purin-6-one | n/a | |
| 39 | P26281_YH4 | YH4 | n/a | 73386657;135566868; | CHEMBL3233209 | 2-amino-8-{[2-(2-methylphenyl)-2-oxoethyl]sulfanyl}-1,7-dihydro-6H-purin-6-one | n/a | |
| 40 | P26281_YH5 | YH5 | n/a | 4282260;135515794; | CHEMBL3233207 | 2-amino-8-{[2-(4-methoxyphenyl)-2-oxoethyl]sulfanyl}-1,9-dihydro-6H-purin-6-one | n/a | |
| 41 | P26281_YH6 | YH6 | n/a | 861222;135548073; | CHEMBL3233203 | 2-amino-8-{[2-(4-methylphenyl)-2-oxoethyl]sulfanyl}-1,7-dihydro-6H-purin-6-one | n/a | |
| 42 | P26281_YH7 | YH7 | n/a | 77209;1502011; | n/a | 6-amino-1,9-dihydro-2H-purine-2-thione | n/a |