Gene name: MAPK3
Protein name: Mitogen-activated protein kinase
List of molecules and drugs that interact with protein P27361
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P27361_38Z | 38Z | n/a | 24866313 | CHEMBL3590107 | (3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-2H-indazol-5-yl]pyrrolidine-3-carboxamide | n/a | |
| 2 | P27361_5ID | 5ID | DB04604 | 97297 | CHEMBL99203 | (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL | n/a | |
| 3 | P27361_6H3 | 6H3 | n/a | 134130572 | CHEMBL3884293 | N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamide | n/a | |
| 4 | P27361_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 5 | P27361_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 6 | P27361_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 7 | P27361_EWH | EWH | n/a | 131801160 | CHEMBL3883384 | ~{N}-[2-[[5-chloranyl-2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide | n/a | |
| 8 | P27361_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 9 | P27361_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 10 | P27361_DB00605 | n/a | DB00605 | n/a | n/a | Sulindac | inhibitor | |
| 11 | P27361_DB01169 | n/a | DB01169 | n/a | n/a | Arsenic trioxide | inducer | |
| 12 | P27361_PVB | PVB | DB02733 | 448991 | CHEMBL23254 | Purvalanol | inhibitor | IC50(nM) = 3300.0 |
| 13 | P27361_RRC | RRC | DB06195 | 160355 | CHEMBL14762 | Seliciclib | n/a | |
| 14 | P27361_EVK | EVK | DB13930 | 11719003 | CHEMBL3590106 | Ulixertinib | inhibitor |