Gene name: DCK
Protein name: Deoxycytidine kinase (dCK)
List of molecules and drugs that interact with protein P27707
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P27707_18V | 18V | n/a | 60202621 | CHEMBL2426558 | 2-[({2-[3-(2-fluoroethoxy)-4-methoxyphenyl]-5-propyl-1,3-thiazol-4-yl}methyl)sulfanyl]pyrimidine-4,6-diamine | n/a | |
| 2 | P27707_1NM | 1NM | n/a | 72706086 | CHEMBL2426582 | 2-[({2-[3-(2-fluoroethoxy)-4-methoxyphenyl]-1,3-thiazol-4-yl}methyl)sulfanyl]pyrimidine-4,6-diamine | n/a | |
| 3 | P27707_1NN | 1NN | n/a | 72706087 | CHEMBL2426598 | 2-[({5-ethyl-2-[3-(2-fluoroethoxy)-4-methoxyphenyl]-1,3-thiazol-4-yl}methyl)sulfanyl]pyrimidine-4,6-diamine | n/a | |
| 4 | P27707_1NO | 1NO | n/a | 60194750 | CHEMBL2426588 | 2-[({2-[3-(2-fluoroethoxy)-4-methoxyphenyl]-5-methyl-1,3-thiazol-4-yl}methyl)sulfanyl]pyrimidine-4,6-diamine | n/a | |
| 5 | P27707_1QC | 1QC | n/a | 73167565 | CHEMBL2426574 | N-{2-[5-(4-{[(4,6-diaminopyrimidin-2-yl)sulfanyl]methyl}-5-propyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]ethyl}methanesulfonamide | n/a | |
| 6 | P27707_1UX | 1UX | n/a | 71710912 | CHEMBL2426573 | 1-[5-(4-{[(4,6-diaminopyrimidin-2-yl)sulfanyl]methyl}-5-propyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]-2-methylpropan-2-ol | n/a | |
| 7 | P27707_2XJ | 2XJ | n/a | 86223070 | CHEMBL3358092 | 1-(5-(4-(((2,6-diaminopyrimidin-4-yl)thio)methyl)-5-propylthiazol-2-yl)-2-methoxyphenoxy)-2-methylpropan-2-ol | n/a | |
| 8 | P27707_2XL | 2XL | n/a | 73292861 | CHEMBL2426568 | 5-(4-(((4,6-diaminopyrimidin-2-yl)thio)methyl)-5-propylthiazol-2-yl)-2-methoxyphenol | n/a | |
| 9 | P27707_2XM | 2XM | n/a | 60202413 | CHEMBL2426567 | 2,2'-((4-(4-(((4,6-diaminopyrimidin-2-yl)thio)methyl)-5-propylthiazol-2-yl)-1,2-phenylene)bis(oxy))bis(ethan-1-ol) | n/a | |
| 10 | P27707_2XN | 2XN | n/a | 86223073 | CHEMBL3358097 | N-{2-[5-(4-{(1R)-1-[(4,6-diaminopyrimidin-2-yl)sulfanyl]ethyl}-5-methyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]ethyl}methanesulfonamide | n/a | |
| 11 | P27707_2XZ | 2XZ | n/a | 60202391 | CHEMBL2426570 | 2-(5-(4-(((4,6-diaminopyrimidin-2-yl)thio)methyl)-5-propylthiazol-2-yl)-2-methoxyphenoxy)ethan-1-ol | n/a | |
| 12 | P27707_2Y0 | 2Y0 | n/a | 73292701 | CHEMBL2426565 | N-(2-(3-(4-(((4,6-diaminopyrimidin-2-yl)thio)methyl)-5-propylthiazol-2-yl)phenoxy)ethyl)methanesulfonamide | n/a | |
| 13 | P27707_2Y1 | 2Y1 | n/a | 90478328 | n/a | (R)-2-((1-(2-(3-(2-fluoroethoxy)-4-methoxyphenyl)-5-propylthiazol-4-yl)ethyl)thio)pyrimidine-4,6-diamine | n/a | |
| 14 | P27707_2Y7 | 2Y7 | n/a | 86223072 | n/a | (S)-2-((1-(2-(3-(2-fluoroethoxy)-4-methoxyphenyl)-5-methylthiazol-4-yl)ethyl)thio)pyrimidine-4,6-diamine | n/a | |
| 15 | P27707_2Y8 | 2Y8 | n/a | 86223071 | n/a | (R)-2-((1-(2-(3-(2-fluoroethoxy)-4-methoxyphenyl)-5-methylthiazol-4-yl)ethyl)thio)pyrimidine-4,6-diamine | n/a | |
| 16 | P27707_3D1 | 3D1 | n/a | 13730 | CHEMBL449329 | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol | n/a | |
| 17 | P27707_3L1 | 3L1 | n/a | 489519 | n/a | (2S,3R,5S)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol | n/a | |
| 18 | P27707_3TC | 3TC | DB00709 | 60825 | CHEMBL141 | 4-AMINO-1-[(2R,5S)-2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL]PYRIMIDIN-2(1H)-ONE | n/a | |
| 19 | P27707_5BT | 5BT | n/a | 472175 | CHEMBL386413 | 5-bromo-2'-deoxycytidine | n/a | |
| 20 | P27707_AC2 | AC2 | DB00787 | 2022;5280999;135398513; | CHEMBL184 | 9-HYROXYETHOXYMETHYLGUANINE | n/a | |
| 21 | P27707_ADP | ADP | DB16833 | 6022 | CHEMBL14830 | ADENOSINE-5'-DIPHOSPHATE | n/a | |
| 22 | P27707_AR3 | AR3 | DB00987 | 6253 | CHEMBL803 | CYTARABINE | n/a | |
| 23 | P27707_B86 | B86 | DB12957 | 515328 | CHEMBL1076257 | 2'-deoxy-5-fluorocytidine | n/a | |
| 24 | P27707_B87 | B87 | n/a | 46846243 | CHEMBL1081559 | 4-(1-benzothiophen-2-yl)-6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]pyrimidine | n/a | |
| 25 | P27707_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 26 | P27707_CFB | CFB | DB00631 | 119182 | CHEMBL1750 | 2-CHLORO-9-(2-DEOXY-2-FLUORO-B -D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE | n/a | |
| 27 | P27707_CL9 | CL9 | DB00242 | 20279 | CHEMBL1619 | 2-chloro-2'-deoxyadenosine | n/a | |
| 28 | P27707_D5M | D5M | n/a | 12599 | CHEMBL1206239 | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE | n/a | |
| 29 | P27707_DCM | DCM | DB03798 | 13945 | CHEMBL374699 | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE | n/a | |
| 30 | P27707_DCZ | DCZ | DB02594 | 13711 | CHEMBL66115 | 2'-DEOXYCYTIDINE | n/a | |
| 31 | P27707_ETV | ETV | DB00879 | 60877 | CHEMBL885 | 4-AMINO-5-FLUORO-1-[(2R,5S)-2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL]PYRIMIDIN-2(1H)-ONE | n/a | |
| 32 | P27707_G65 | G65 | DB11526 | 10074640 | CHEMBL1908391 | Masitinib | n/a | |
| 33 | P27707_GEO | GEO | DB00441 | 60750 | CHEMBL888 | GEMCITABINE | n/a | |
| 34 | P27707_GNG | GNG | n/a | 187790;5274261;135398592; | CHEMBL68908 | 2'-DEOXY-GUANOSINE | n/a | |
| 35 | P27707_J29 | J29 | n/a | 168268162 | n/a | 2-[2-[[2-methyl-5-[6-(4-methylpiperazin-1-yl)sulfonylpyridin-3-yl]phenyl]-propyl-amino]-1,3-thiazol-4-yl]pyrimidine-4,6-diamine | n/a | |
| 36 | P27707_J5U | J5U | n/a | 168268160 | n/a | 2-[2-[[2-methyl-5-[6-[2-(4-methylpiperazin-1-yl)ethyl]pyridin-3-yl]phenyl]-propyl-amino]-1,3-thiazol-4-yl]pyrimidine-4,6-diamine | n/a | |
| 37 | P27707_J6M | J6M | n/a | 168268161 | n/a | 2-[2-[[2-methyl-5-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]phenyl]-propyl-amino]-1,3-thiazol-4-yl]pyrimidine-4,6-diamine | n/a | |
| 38 | P27707_J7I | J7I | n/a | 168268163 | n/a | 2-[2-[[5-[3-methoxy-4-(4-methylpiperazin-1-yl)sulfonyl-phenyl]-2-methyl-phenyl]-propyl-amino]-1,3-thiazol-4-yl]pyrimidine-4,6-diamine | n/a | |
| 39 | P27707_J7W | J7W | n/a | 168268155 | n/a | N-[3-[[4-[4,6-bis(azanyl)pyrimidin-2-yl]-1,3-thiazol-2-yl]amino]-4-methyl-phenyl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide | n/a | |
| 40 | P27707_J98 | J98 | n/a | 168268156 | n/a | 2-[2-[[2-methyl-5-[4-(4-methylpiperazin-1-yl)sulfonyl-2-(trifluoromethyl)phenyl]phenyl]-propyl-amino]-1,3-thiazol-4-yl]pyrimidine-4,6-diamine | n/a | |
| 41 | P27707_J9I | J9I | n/a | 168268157 | n/a | 4-(4-azanylpyrimidin-2-yl)-N-[2-methyl-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]-1,3-thiazol-2-amine | n/a | |
| 42 | P27707_JAQ | JAQ | n/a | 168268158 | n/a | 4-(4-azanylpyrimidin-2-yl)-N-[2-methyl-5-[4-[2-(4-methylpiperazin-1-yl)ethyl]phenyl]phenyl]-1,3-thiazol-2-amine | n/a | |
| 43 | P27707_JCA | JCA | n/a | 168268154 | n/a | N-[3-[[4-(4-azanylpyrimidin-2-yl)-1,3-thiazol-2-yl]amino]-4-methyl-phenyl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide | n/a | |
| 44 | P27707_JCM | JCM | n/a | 168268159 | n/a | 4-(4-azanylpyrimidin-2-yl)-N-[2-methyl-5-[4-[2-(4-methylpiperazin-1-yl)ethyl]phenyl]phenyl]-N-propyl-1,3-thiazol-2-amine | n/a | |
| 45 | P27707_LDC | LDC | n/a | 159354 | CHEMBL554563 | 4-AMINO-1-(2-DEOXY-BETA-L-ERYTHRO-PENTOFURANOSYL)PYRIMIDIN-2(1H)-ONE | n/a | |
| 46 | P27707_LLT | LLT | DB01265 | 159269 | CHEMBL374731 | L-deoxythymidine | n/a | |
| 47 | P27707_LTT | LTT | DB04961 | 454194 | CHEMBL359164 | 4-AMINO-1-[(2S,4S)-2-(HYDROXYMETHYL)-1,3-DIOXOLAN-4-YL]PYRIMIDIN-2(1H)-ONE | n/a | |
| 48 | P27707_MCY | MCY | n/a | 440055 | CHEMBL1234242 | 5-METHYL-2'-DEOXYCYTIDINE | n/a | |
| 49 | P27707_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 50 | P27707_MLT | MLT | DB03499 | 92824 | CHEMBL225986 | D-MALATE | n/a | |
| 51 | P27707_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 52 | P27707_UDP | UDP | DB03435 | 6031;146015339; | CHEMBL130266 | URIDINE-5'-DIPHOSPHATE | n/a | |
| 53 | P27707_UMP | UMP | DB03800 | 65063 | CHEMBL211312 | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | n/a | |
| 54 | P27707_STI | STI | DB00619 | 5291 | CHEMBL941 | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE | n/a | |
| 55 | P27707_DB01073 | n/a | DB01073 | n/a | n/a | Fludarabine | agonist | |
| 56 | P27707_DB05494 | n/a | DB05494 | n/a | n/a | Elacytarabine | n/a |