Gene name: PDE4A
Protein name: 3',5'-cyclic-AMP phosphodiesterase 4A
List of molecules and drugs that interact with protein P27815
# | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
---|---|---|---|---|---|---|---|---|
1 | P27815_0MO | 0MO | DB06842 | 6603746 | CHEMBL1229585 | (4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one | n/a | |
2 | P27815_CO | CO | n/a | 104729 | n/a | COBALT (II) ION | n/a | |
3 | P27815_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
4 | P27815_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
5 | P27815_PNX | PNX | DB00806 | 4740 | CHEMBL628 | 3,7-DIMETHYL-1-(5-OXOHEXYL)-3,7-DIHYDRO-1H-PURINE-2,6-DIONE | n/a | IC50(nM) = 168000.0 |
6 | P27815_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
7 | P27815_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
8 | P27815_TEP | TEP | DB00277 | 2153 | CHEMBL190 | Theophylline | inhibitor | IC50(nM) = 386000.0 |
9 | P27815_DB00651 | n/a | DB00651 | n/a | n/a | Dyphylline | inhibitor | |
10 | P27815_DB00824 | n/a | DB00824 | n/a | n/a | Enprofylline | inhibitor | |
11 | P27815_H9F | H9F | DB00975 | 3108 | CHEMBL932 | Dipyridamole | inhibitor | |
12 | P27815_DB01088 | n/a | DB01088 | n/a | n/a | Iloprost | inducer | |
13 | P27815_DB01303 | n/a | DB01303 | n/a | n/a | Oxtriphylline | inhibitor | |
14 | P27815_PIL | PIL | DB01791 | 154575 | CHEMBL42126 | Piclamilast | inhibitor | IC50(nM) = 1.6 |
15 | P27815_DB05219 | n/a | DB05219 | n/a | n/a | Crisaborole | inhibitor | |
16 | P27815_AVL | AVL | DB05266 | 3671 | CHEMBL19449 | Ibudilast | inhibitor | IC50(nM) = 54.0 EC50(nM) = 900.0 |
17 | P27815_POY | POY | DB06479 | 4938 | CHEMBL1079905 | Propentofylline | n/a | |
18 | P27815_DB06751 | n/a | DB06751 | n/a | n/a | Drotaverine | inhibitor | |
19 | P27815_NPV | NPV | DB08299 | 9999276 | CHEMBL74078 | 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid | n/a | IC50(nM) = 29.0 EC50(nM) = 20.0 |
20 | P27815_JPU | JPU | DB08811 | 5502 | CHEMBL404216 | Tofisopam | inhibitor |