P27815 PDE4A_HUMAN
Gene name: PDE4A
Protein name: 3',5'-cyclic-AMP phosphodiesterase 4A

List of molecules and drugs that interact with protein P27815

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 P27815_0MO 0MO DB06842 6603746 CHEMBL1229585 (4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one n/a
2 P27815_CO CO n/a 104729 n/a COBALT (II) ION n/a
3 P27815_GOL GOL DB09462 753 CHEMBL692 GLYCEROL n/a
4 P27815_MG MG n/a 888 n/a MAGNESIUM ION n/a
5 P27815_PNX PNX DB00806 4740 CHEMBL628 3,7-DIMETHYL-1-(5-OXOHEXYL)-3,7-DIHYDRO-1H-PURINE-2,6-DIONE n/a IC50(nM) = 168000.0
6 P27815_SO4 SO4 DB14546 1117 n/a SULFATE ION n/a
7 P27815_ZN ZN n/a 32051 CHEMBL1236970 ZINC ION n/a
8 P27815_TEP TEP DB00277 2153 CHEMBL190 Theophylline inhibitor IC50(nM) = 386000.0
9 P27815_DB00651 n/a DB00651 n/a n/a Dyphylline inhibitor
10 P27815_DB00824 n/a DB00824 n/a n/a Enprofylline inhibitor
11 P27815_H9F H9F DB00975 3108 CHEMBL932 Dipyridamole inhibitor
12 P27815_DB01088 n/a DB01088 n/a n/a Iloprost inducer
13 P27815_DB01303 n/a DB01303 n/a n/a Oxtriphylline inhibitor
14 P27815_PIL PIL DB01791 154575 CHEMBL42126 Piclamilast inhibitor IC50(nM) = 1.6
15 P27815_DB05219 n/a DB05219 n/a n/a Crisaborole inhibitor
16 P27815_AVL AVL DB05266 3671 CHEMBL19449 Ibudilast inhibitor IC50(nM) = 54.0
EC50(nM) = 900.0
17 P27815_POY POY DB06479 4938 CHEMBL1079905 Propentofylline n/a
18 P27815_DB06751 n/a DB06751 n/a n/a Drotaverine inhibitor
19 P27815_NPV NPV DB08299 9999276 CHEMBL74078 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid n/a IC50(nM) = 29.0
EC50(nM) = 20.0
20 P27815_JPU JPU DB08811 5502 CHEMBL404216 Tofisopam inhibitor