Gene name: PSMB8
Protein name: Proteasome subunit beta
List of molecules and drugs that interact with protein P28062
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P28062_04C | 04C | n/a | 137347833 | n/a | 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol | n/a | |
| 2 | P28062_38X | 38X | n/a | 137348133 | n/a | N-[(3-methyl-1H-inden-2-yl)carbonyl]-D-alanyl-N-[(2S,4R)-1-cyclohexyl-5-hydroxy-4-methyl-3-oxopentan-2-yl]-L-tryptophanamide | n/a | |
| 3 | P28062_39V | 39V | n/a | 137348136 | n/a | N-[(3-methyl-1H-inden-2-yl)carbonyl]-D-alanyl-N-[(2S,4R)-5-hydroxy-4-methyl-3-oxo-1-phenylpentan-2-yl]-L-tryptophanamide | n/a | |
| 4 | P28062_3BV | 3BV | n/a | 137348138 | n/a | N-{(2S)-2-[(morpholin-4-ylacetyl)amino]-4-phenylbutanoyl}-L-leucyl-N-[(2R,3S,4S)-1,3-dihydroxy-2,6-dimethylheptan-4-yl]-L-phenylalaninamide | n/a | |
| 5 | P28062_6N5 | 6N5 | n/a | 137348493 | n/a | ~{N}-[(2~{S})-1-[[(2~{S})-3-(4-methoxyphenyl)-1-[[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]amino]-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-1-methyl-5~{H}-indene-2-carboxamide | n/a | |
| 6 | P28062_6NV | 6NV | n/a | 137348497 | n/a | ~{N}-[(2~{R})-1-[[(2~{S})-3-(4-methoxyphenyl)-1-[[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]amino]-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-1-methyl-5~{H}-indene-2-carboxamide | n/a | |
| 7 | P28062_79L | 79L | n/a | 117072194 | n/a | (2~{S})-3-(4-methoxyphenyl)-~{N}-[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]-2-[[(2~{R})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide | n/a | |
| 8 | P28062_79P | 79P | n/a | 137348578 | n/a | (2~{S})-3-(1~{H}-indol-3-yl)-~{N}-[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]-2-[[(2~{R})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide | n/a | |
| 9 | P28062_7DX | 7DX | n/a | 124037109 | n/a | (2~{S})-2-cyclohexyl-4-oxidanylidene-4-[[7-(4-phenyl-1,3-thiazol-2-yl)quinolin-2-yl]amino]butanoic acid | n/a | |
| 10 | P28062_BO2 | BO2 | DB00188 | 387447 | CHEMBL325041 | N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE | n/a | IC50(nM) = 1.3 |
| 11 | P28062_BZ7 | BZ7 | n/a | 129047819 | CHEMBL4564752 | N~1~-{2-[([1,1'-biphenyl]-3-carbonyl)amino]ethyl}-N~4~-tert-butyl-N~2~-(3-phenylpropanoyl)-L-aspartamide | n/a | |
| 12 | P28062_HUJ | HUJ | n/a | n/a | n/a | [(1R)-3-methyl-1-[[1-[2-[(2,3,4-trimethoxyphenyl)carbonylamino]ethyl]-1,2,3-triazol-4-yl]carbonylamino]butyl]-tris(oxidanyl)boron | n/a | |
| 13 | P28062_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 14 | P28062_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 15 | P28062_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 16 | P28062_S5K | S5K | n/a | 138319683 | CHEMBL5184466 | [(1R)-2-(1-benzofuran-3-yl)-1-{[(1S,2R,4R)-7-oxabicyclo[2.2.1]heptan-2-yl]formamido}ethyl]boronic acid | n/a | |
| 17 | P28062_SCN | SCN | n/a | 9322 | n/a | THIOCYANATE ION | n/a | |
| 18 | P28062_SKN | SKN | n/a | 157049321 | CHEMBL5188533 | ((R)-2-(3-ethylphenyl)-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)ethyl)boronic acid | n/a | |
| 19 | P28062_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 20 | P28062_DB08889 | n/a | DB08889 | n/a | n/a | Carfilzomib | inhibitor | IC50(nM) = 3.2 |