Gene name: PSMB5
Protein name: Proteasome subunit beta
List of molecules and drugs that interact with protein P28074
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P28074_04C | 04C | n/a | 137347833 | n/a | 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol | n/a | |
| 2 | P28074_1PE | 1PE | n/a | 62551 | CHEMBL1229766 | PENTAETHYLENE GLYCOL | n/a | |
| 3 | P28074_39V | 39V | n/a | 137348136 | n/a | N-[(3-methyl-1H-inden-2-yl)carbonyl]-D-alanyl-N-[(2S,4R)-5-hydroxy-4-methyl-3-oxo-1-phenylpentan-2-yl]-L-tryptophanamide | n/a | |
| 4 | P28074_3BV | 3BV | n/a | 137348138 | n/a | N-{(2S)-2-[(morpholin-4-ylacetyl)amino]-4-phenylbutanoyl}-L-leucyl-N-[(2R,3S,4S)-1,3-dihydroxy-2,6-dimethylheptan-4-yl]-L-phenylalaninamide | n/a | |
| 5 | P28074_6N5 | 6N5 | n/a | 137348493 | n/a | ~{N}-[(2~{S})-1-[[(2~{S})-3-(4-methoxyphenyl)-1-[[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]amino]-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-1-methyl-5~{H}-indene-2-carboxamide | n/a | |
| 6 | P28074_6NV | 6NV | n/a | 137348497 | n/a | ~{N}-[(2~{R})-1-[[(2~{S})-3-(4-methoxyphenyl)-1-[[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]amino]-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-1-methyl-5~{H}-indene-2-carboxamide | n/a | |
| 7 | P28074_6V7 | 6V7 | n/a | 124645820 | n/a | [(1~{R})-3-methyl-1-[[(2~{S},3~{S})-3-oxidanyl-2-[(6-phenylpyridin-2-yl)carbonylamino]butanoyl]amino]butyl]boronic acid | n/a | |
| 8 | P28074_6V8 | 6V8 | DB09570 | 25183872 | CHEMBL2141296 | [(1~{R})-1-[2-[[2,5-bis(chloranyl)phenyl]carbonylamino]ethanoylamino]-3-methyl-butyl]boronic acid | inhibitor | |
| 9 | P28074_6VC | 6VC | n/a | 137348532 | n/a | ~{N}-[(2~{S})-1-[[(2~{S},3~{R},4~{S})-2,6-dimethyl-1,2,3-tris(oxidanyl)heptan-4-yl]amino]-3-oxidanyl-1-oxidanylidene-propan-2-yl]-6-methyl-heptanamide | n/a | |
| 10 | P28074_79P | 79P | n/a | 137348578 | n/a | (2~{S})-3-(1~{H}-indol-3-yl)-~{N}-[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]-2-[[(2~{R})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide | n/a | |
| 11 | P28074_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 12 | P28074_BO2 | BO2 | DB00188 | 387447 | CHEMBL325041 | N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE | inhibitor | Ki(nM) = 0.6 IC50(nM) = 0.5 |
| 13 | P28074_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 14 | P28074_KNM | KNM | n/a | 137349651 | n/a | ADA-(AHX)3-(LEU)3-VINYL SULFONE | n/a | |
| 15 | P28074_LDZ | LDZ | n/a | 462382 | CHEMBL64925 | N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-L-leucinamide | n/a | |
| 16 | P28074_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 17 | P28074_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 18 | P28074_YHD | YHD | n/a | 156600317 | n/a | N-[(1R)-2-([1,1'-biphenyl]-4-yl)-1-boronoethyl]-1-methyl-L-prolinamide | n/a | |
| 19 | P28074_SA1 | SA1 | DB08515 | 11840981 | n/a | (3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE | n/a | |
| 20 | P28074_DB08889 | n/a | DB08889 | n/a | n/a | Carfilzomib | inhibitor | IC50(nM) = 2.1 |