P28222 5HT1B_HUMAN
Gene name: HTR1B
Protein name: 5-hydroxytryptamine receptor 1B

List of molecules and drugs that interact with protein P28222

#	DrugDomain Data	PBD ligand	DrugBank Accession	PubChem	ChEMBL	Name	Drug action	Affinity data
1	P28222_2GM	2GM	DB00320	10531	CHEMBL1732	Dihydroergotamine	agonist
2	P28222_89F	89F	n/a	7059581	CHEMBL428892	1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine	n/a
3	P28222_EP5	EP5	n/a	137349273	n/a	2-[5-[2-[4-(4-cyanophenyl)piperazin-1-yl]-2-oxidanylidene-ethoxy]-1~{H}-indol-3-yl]ethylazanium	n/a
4	P28222_ERM	ERM	DB00696	8223	CHEMBL442	Ergotamine	agonist	Ki(nM) = 2.1
5	P28222_OLB	OLB	n/a	12178130	n/a	(2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate	n/a
6	P28222_DB00216	n/a	DB00216	n/a	n/a	Eletriptan	agonist	EC50(nM) = 12.0
7	P28222_DB00246	n/a	DB00246	n/a	n/a	Ziprasidone	antagonist	Ki(nM) = 0.99
8	P28222_DB00247	n/a	DB00247	n/a	n/a	Methysergide	binder
9	P28222_DB00248	n/a	DB00248	n/a	n/a	Cabergoline	agonist
10	P28222_DB00315	n/a	DB00315	n/a	n/a	Zolmitriptan	agonist	Ki(nM) = 0.4 IC50(nM) = 6.2 Kd(nM) = 1.5 EC50(nM) = 16.0
11	P28222_TP0	TP0	DB00321	2160	CHEMBL629	Amitriptyline	binder
12	P28222_DB00363	n/a	DB00363	n/a	n/a	Clozapine	antagonist
13	P28222_DB00408	n/a	DB00408	n/a	n/a	Loxapine	binder
14	P28222_DB00543	n/a	DB00543	n/a	n/a	Amoxapine	antagonist
15	P28222_DB00571	n/a	DB00571	n/a	n/a	Propranolol	other/unknown	Ki(nM) = 56.23 IC50(nM) = 5012.0 EC50(nM) = 5012.0
16	P28222_H8G	H8G	DB00589	28864	CHEMBL157138	Lisuride	agonist	Ki(nM) = 16.0
17	P28222_DB00669	n/a	DB00669	n/a	n/a	Sumatriptan	agonist	Ki(nM) = 0.5 IC50(nM) = 0.501187 EC50(nM) = 38.0
18	P28222_OR9	OR9	DB00714	6005	CHEMBL53	Apomorphine	agonist	Ki(nM) = 2951.21
19	P28222_S87	S87	DB00904	4595	CHEMBL46	Ondansetron	other/unknown
20	P28222_DB00918	n/a	DB00918	n/a	n/a	Almotriptan	agonist
21	P28222_J5C	J5C	DB00935	4636	CHEMBL762	Oxymetazoline	agonist	Ki(nM) = 0.26
22	P28222_DB00952	n/a	DB00952	n/a	n/a	Naratriptan	agonist	Ki(nM) = 1.5
23	P28222_DB00953	n/a	DB00953	n/a	n/a	Rizatriptan	agonist	Ki(nM) = 3.0 IC50(nM) = 41.0
24	P28222_DB00960	n/a	DB00960	n/a	n/a	Pindolol	other/unknown	Ki(nM) = 2600.0
25	P28222_DB00998	n/a	DB00998	n/a	n/a	Frovatriptan	agonist	Ki(nM) = 4.4
26	P28222_DB01186	n/a	DB01186	n/a	n/a	Pergolide	agonist	Ki(nM) = 281.84
27	P28222_08Y	08Y	DB01200	31101	CHEMBL493	Bromocriptine	agonist	Ki(nM) = 354.81
28	P28222_DB01224	n/a	DB01224	n/a	n/a	Quetiapine	ligand	Ki(nM) = 2050.0
29	P28222_9SC	9SC	DB01238	60795	CHEMBL1112	Aripiprazole	antagonist	Ki(nM) = 830.0
30	P28222_DB01359	n/a	DB01359	n/a	n/a	Penbutolol	antagonist
31	P28222_DB01392	n/a	DB01392	n/a	n/a	Yohimbine	partial agonist	Ki(nM) = 5.0
32	P28222_DB04884	n/a	DB04884	n/a	n/a	Dapoxetine	n/a
33	P28222_DB06153	n/a	DB06153	n/a	n/a	Pizotifen	antagonist
34	P28222_DB06216	n/a	DB06216	n/a	n/a	Asenapine	antagonist	Ki(nM) = 3.9
35	P28222_DB08804	n/a	DB08804	n/a	n/a	Nandrolone decanoate	modulator
36	P28222_DB08807	n/a	DB08807	n/a	n/a	Bopindolol	n/a
37	P28222_DB09068	n/a	DB09068	n/a	n/a	Vortioxetine	partial agonist
38	P28222_DB14185	n/a	DB14185	n/a	n/a	Aripiprazole lauroxil	n/a