Gene name: MAPK1
Protein name: Mitogen-activated protein kinase
List of molecules and drugs that interact with protein P28482
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P28482_08G | 08G | n/a | n/a | n/a | 1-[4-(hydroxymethyl)-1H-pyrazolo[4,3-c]pyridin-6-yl]-3-[(1S)-1-phenylethyl]urea | n/a | |
| 2 | P28482_19A | 19A | DB06877 | 1473242 | CHEMBL219841 | N,N-DIMETHYL-4-(4-PHENYL-1H-PYRAZOL-3-YL)-1H-PYRROLE-2-CARBOXAMIDE | n/a | Ki(nM) = 2300.0 |
| 3 | P28482_1FM | 1FM | n/a | 9863776 | CHEMBL1077979 | (3S,5Z,8S,9S,11E)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione | n/a | |
| 4 | P28482_2AI | 2AI | n/a | 82140 | CHEMBL291627 | 1H-imidazol-2-amine | n/a | |
| 5 | P28482_2SH | 2SH | n/a | 60198532 | CHEMBL3298414 | N-[(1S)-1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl]-2-(tetrahydro-2H-pyran-4-ylamino)-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxamide | n/a | |
| 6 | P28482_33A | 33A | DB07010 | 135449325 | CHEMBL220320 | N-BENZYL-4-[4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL]-1H-PYRROLE-2-CARBOXAMIDE | n/a | Ki(nM) = 85.0 |
| 7 | P28482_35W | 35W | n/a | 73777037 | CHEMBL3628383 | 7-(1-benzyl-1H-pyrazol-4-yl)-2-(pyridin-4-yl)-5H-pyrrolo[2,3-b]pyrazine | n/a | |
| 8 | P28482_35X | 35X | n/a | 90106032 | CHEMBL3628378 | 7-(1-propyl-1H-pyrazol-4-yl)-2-(pyridin-4-yl)-5H-pyrrolo[2,3-b]pyrazine | n/a | |
| 9 | P28482_362 | 362 | n/a | 90104994 | CHEMBL3628368 | 2-(1H-pyrazol-4-yl)-7-(pyridin-3-yl)-5H-pyrrolo[2,3-b]pyrazine | n/a | |
| 10 | P28482_363 | 363 | n/a | 90105293 | CHEMBL3628361 | 2-(1H-pyrazol-4-yl)-5H-pyrrolo[2,3-b]pyrazine | n/a | |
| 11 | P28482_36N | 36N | n/a | 5370803 | CHEMBL3628246 | 5H-pyrrolo[2,3-b]pyrazine | n/a | |
| 12 | P28482_36O | 36O | n/a | 658219 | CHEMBL1500217 | N-cyclohexyl-9H-purin-6-amine | n/a | |
| 13 | P28482_36Q | 36Q | n/a | 57250213 | n/a | (2S)-3-phenyl-2-(9H-purin-6-ylamino)propan-1-ol | n/a | |
| 14 | P28482_36R | 36R | DB19372 | 6103 | CHEMBL472566 | 5-chloro-1,3-benzoxazol-2-amine | n/a | |
| 15 | P28482_38Z | 38Z | n/a | 24866313 | CHEMBL3590107 | (3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-2H-indazol-5-yl]pyrrolidine-3-carboxamide | n/a | |
| 16 | P28482_390 | 390 | n/a | 11634725 | CHEMBL583042 | 4-{2-[(2-chloro-4-fluorophenyl)amino]-5-methylpyrimidin-4-yl}-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide | n/a | |
| 17 | P28482_41B | 41B | n/a | 71727133 | CHEMBL3409588 | 1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-(tetrahydro-2H-pyran-4-ylamino)pyrimidin-4-yl]pyridin-2(1H)-one | n/a | |
| 18 | P28482_4V8 | 4V8 | n/a | 91819624 | CHEMBL3604847 | 1-benzyl-4-[3-(pyridin-4-yl)-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl]pyridin-2(1H)-one | n/a | |
| 19 | P28482_4V9 | 4V9 | n/a | 91819625 | CHEMBL3604843 | 3-(4-fluorophenyl)-5-(pyridin-2-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine | n/a | |
| 20 | P28482_4VB | 4VB | n/a | 91819626 | CHEMBL3604856 | 4-[3-(pyridin-4-yl)-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl]pyridin-2(1H)-one | n/a | |
| 21 | P28482_4VF | 4VF | n/a | 91864560 | CHEMBL3608591 | 2-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-7-[2-(tetrahydro-2H-pyran-4-ylamino)pyrimidin-4-yl]-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one | n/a | |
| 22 | P28482_4VG | 4VG | n/a | 91864561 | CHEMBL3608588 | 2-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-8-[2-(tetrahydro-2H-pyran-4-ylamino)pyrimidin-4-yl]-2,3,4,5-tetrahydro-1H-pyrrolo[1,2-a][1,4]diazepin-1-one | n/a | |
| 23 | P28482_4VJ | 4VJ | n/a | 91864562 | CHEMBL3608461 | 2-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-8-(2-{[(1S,3R)-3-hydroxycyclopentyl]amino}pyrimidin-4-yl)-2,3,4,5-tetrahydro-1H-pyrrolo[1,2-a][1,4]diazepin-1-one | n/a | |
| 24 | P28482_5ID | 5ID | DB04604 | 97297 | CHEMBL99203 | (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL | n/a | Ki(nM) = 530.0 IC50(nM) = 1200.0 |
| 25 | P28482_6GI | 6GI | n/a | 25324382;135903377; | n/a | 13-[4-({Imidazo[1,2-a]pyridin-2-yl}methoxy)phenyl]-4,8-dioxa-12,14,16,18-tetraazatetracyclo[9.7.0.0^{3,9}.0^{12,17}]octadeca-1(11),2,9,15,17-pentaen-15-amine | n/a | |
| 26 | P28482_6H3 | 6H3 | n/a | 134130572 | CHEMBL3884293 | N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamide | n/a | |
| 27 | P28482_6QB | 6QB | DB15281 | 71727581 | CHEMBL3544964 | 1-[(1~{S})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one | modulator | |
| 28 | P28482_6TS | 6TS | n/a | 137348521 | n/a | [(1~{R},4~{Z})-cyclooct-4-en-1-yl] ~{N}-[4-[4-[[5-chloranyl-4-[[2-(propanoylamino)phenyl]amino]pyrimidin-2-yl]amino]pyridin-2-yl]but-3-ynyl]carbamate | n/a | |
| 29 | P28482_6TT | 6TT | n/a | 137348522 | n/a | ~{N}-[2-[[2-[(5-methoxypyridin-3-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]propanamide | n/a | |
| 30 | P28482_82A | 82A | DB07264 | 135449326 | CHEMBL387385 | (S)-N-(1-(3-CHLORO-4-FLUOROPHENYL)-2-HYDROXYETHYL)-4-(4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL)-1H-PYRROLE-2-CARBOXAMIDE | n/a | Ki(nM) = 2.0 |
| 31 | P28482_8DK | 8DK | n/a | 16815741 | CHEMBL3753529 | N-(1,3-benzodioxol-5-ylmethyl)-2-[3-(3,4-dimethylphenyl)-7-oxidanylidene-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl]ethanamide | n/a | |
| 32 | P28482_8QB | 8QB | n/a | 126480566 | CHEMBL4072622 | 7-[2-(oxan-4-ylamino)pyrimidin-4-yl]-3,4-dihydro-2~{H}-pyrrolo[1,2-a]pyrazin-1-one | n/a | |
| 33 | P28482_8X2 | 8X2 | n/a | 137348765 | CHEMBL4105185 | 2-[2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one | n/a | |
| 34 | P28482_8X5 | 8X5 | n/a | 126480560 | CHEMBL4097186 | 2-[2-(oxan-4-ylamino)pyrimidin-4-yl]-5-(phenylmethyl)-6,7-dihydro-1~{H}-pyrrolo[3,2-c]pyridin-4-one | n/a | |
| 35 | P28482_8XB | 8XB | n/a | 126480563 | CHEMBL4065992 | (6~{R})-5-(2-methoxyethyl)-6-methyl-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydro-1~{H}-pyrrolo[3,2-c]pyridin-4-one | n/a | |
| 36 | P28482_8XE | 8XE | n/a | 126480562 | CHEMBL4074311 | 5-(2-methoxyethyl)-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydro-1~{H}-pyrrolo[3,2-c]pyridin-4-one | n/a | |
| 37 | P28482_8XH | 8XH | n/a | 126480561 | CHEMBL4074437 | 5-(2-methoxyethyl)-2-[2-(oxan-4-ylamino)pyrimidin-4-yl]-6,7-dihydro-1~{H}-pyrrolo[3,2-c]pyridin-4-one | n/a | |
| 38 | P28482_8XK | 8XK | n/a | 126480565 | CHEMBL4061051 | 5-(2-methoxyethyl)-1-methyl-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydropyrrolo[3,2-c]pyridin-4-one | n/a | |
| 39 | P28482_8XN | 8XN | n/a | 126480564 | CHEMBL4087393 | (6~{S})-5-(2-methoxyethyl)-6-methyl-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydro-1~{H}-pyrrolo[3,2-c]pyridin-4-one | n/a | |
| 40 | P28482_90A | 90A | n/a | 59862050 | n/a | 2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oic acid | n/a | |
| 41 | P28482_ACP | ACP | DB03909 | 91532 | CHEMBL133463 | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | n/a | |
| 42 | P28482_ADP | ADP | DB16833 | 6022 | CHEMBL14830 | ADENOSINE-5'-DIPHOSPHATE | n/a | |
| 43 | P28482_AKS | AKS | n/a | 103758038 | n/a | N-(hex-5-yn-1-yl)hexanamide | n/a | |
| 44 | P28482_ANP | ANP | n/a | 33113 | CHEMBL1230989 | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | n/a | |
| 45 | P28482_B7S | B7S | n/a | 5281343 | CHEMBL3604316 | 5,7-dihydroxy-4H-1-benzopyran-4-one | n/a | |
| 46 | P28482_B8Z | B8Z | n/a | 24672456 | CHEMBL3752694 | ~{N}-(5,6-dimethoxy-1,3-benzothiazol-2-yl)-2-[(4-fluoranylphenoxy)methyl]-1,3-thiazole-4-carboxamide | n/a | |
| 47 | P28482_BEZ | BEZ | DB03793 | 243;20144841; | CHEMBL541 | BENZOIC ACID | n/a | |
| 48 | P28482_BTB | BTB | n/a | 81462 | n/a | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 49 | P28482_CAQ | CAQ | DB02232 | 289 | CHEMBL280998 | CATECHOL | n/a | |
| 50 | P28482_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 51 | P28482_CQ3 | CQ3 | n/a | 122181361 | CHEMBL3590119 | N-[2-[[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]amino]phenyl]propanamide | n/a | |
| 52 | P28482_CQ6 | CQ6 | n/a | 122181357 | CHEMBL3590112 | 7-ethylsulfonyl-N-(oxan-4-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-amine | n/a | |
| 53 | P28482_CQ8 | CQ8 | n/a | 91758407 | CHEMBL3590115 | 2-[[5-chloranyl-2-(oxan-4-ylamino)pyridin-4-yl]amino]-N-methyl-benzamide | n/a | |
| 54 | P28482_DHC | DHC | DB01880 | 689043 | CHEMBL145 | CAFFEIC ACID | n/a | |
| 55 | P28482_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 56 | P28482_E28 | E28 | n/a | 135566747 | n/a | 4-{4-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl}-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-1H-pyrrole-2-carboxamide | n/a | |
| 57 | P28482_E57 | E57 | n/a | 60147038 | n/a | N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-4-(2-{[(2S)-1-hydroxybutan-2-yl]amino}-5-methylpyrimidin-4-yl)-1H-pyrrole-2-carboxamide | n/a | |
| 58 | P28482_E63 | E63 | n/a | 57498060 | n/a | 6-({4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]-5-(phenylamino)pyrimidin-2-yl}amino)-1,2-dihydro-3H-indazol-3-one | n/a | |
| 59 | P28482_E71 | E71 | n/a | 135566739 | n/a | 3-[4-(2,3-difluorophenyl)-1,2-oxazol-5-yl]-5-(pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine | n/a | |
| 60 | P28482_E75 | E75 | n/a | n/a | n/a | trans-4-{[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)pyrimidin-2-yl]amino}cyclohexanol | n/a | |
| 61 | P28482_E86 | E86 | n/a | 44481490 | CHEMBL571038 | 4-{2-[(2-chlorophenyl)amino]-5-methylpyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-phenylethyl]-1H-pyrrole-2-carboxamide | n/a | |
| 62 | P28482_E94 | E94 | n/a | 60147039 | n/a | 4-(3-chlorophenyl)-5-{2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}-2-{[2-(piperidin-1-yl)ethyl]amino}thiophene-3-carbonitrile | n/a | |
| 63 | P28482_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 64 | P28482_EK0 | EK0 | n/a | 2767228 | CHEMBL1571228 | 3-(4-chlorophenyl)-4,5,6,7-tetrahydro-1H-indazole | n/a | |
| 65 | P28482_EK2 | EK2 | n/a | 135433066 | n/a | {4-[4-(3,5-dichlorophenyl)-1H-pyrazol-5-yl]-1H-pyrrol-2-yl}(morpholin-4-yl)methanone | n/a | |
| 66 | P28482_EK3 | EK3 | n/a | 60138179 | n/a | N-cyclohexyl-4-[3-(4-fluorophenyl)-1H-pyrazol-4-yl]pyridin-2-amine | n/a | |
| 67 | P28482_EK4 | EK4 | n/a | 136259527 | n/a | N-[(1S)-2-hydroxy-1-phenylethyl]-4-{4-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl}-1H-pyrrole-2-carboxamide | n/a | |
| 68 | P28482_EK5 | EK5 | n/a | 135566737 | n/a | 4-[4-(3-chlorophenyl)-1H-pyrazol-5-yl]-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-1H-pyrrole-2-carboxamide | n/a | |
| 69 | P28482_EK6 | EK6 | n/a | 135566738 | n/a | ethyl N-{2-chloro-4-[5-(5-{[(1S)-1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl]carbamoyl}-1H-pyrrol-3-yl)-1H-pyrazol-4-yl]benzyl}glycinate | n/a | |
| 70 | P28482_EK7 | EK7 | n/a | 11473947 | n/a | 9-(dimethylamino)-2-[(3-hydroxyphenyl)amino]-5,6-dihydrothieno[3,4-h]quinazoline-7-carbonitrile | n/a | |
| 71 | P28482_EK9 | EK9 | n/a | 9865610 | n/a | N-[(1S)-2-hydroxy-1-phenylethyl]-4-(5-methyl-2-phenylpyrimidin-4-yl)-1H-pyrrole-2-carboxamide | n/a | |
| 72 | P28482_EMU | EMU | n/a | 62389 | CHEMBL228862 | N-BENZYL-9H-PURIN-6-AMINE | n/a | |
| 73 | P28482_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 74 | P28482_EQT | EQT | n/a | 313444 | CHEMBL1333961 | 4-chloranyl-1~{H}-indazol-3-amine | n/a | |
| 75 | P28482_EQW | EQW | n/a | 79557014 | CHEMBL4205466 | 5-chloranyl-~{N}-(oxan-4-yl)pyrimidin-2-amine | n/a | |
| 76 | P28482_EQZ | EQZ | n/a | 129053136 | CHEMBL4217740 | 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2-(2-methoxyethyl)-3~{H}-isoindol-1-one | n/a | |
| 77 | P28482_ER8 | ER8 | n/a | 129053305 | CHEMBL4215376 | ~{N}-~{tert}-butyl-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]ethanamide | n/a | |
| 78 | P28482_ERK | ERK | n/a | 129077199 | CHEMBL4207117 | 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-[(1~{R})-1-phenylethyl]ethanamide | n/a | |
| 79 | P28482_ERW | ERW | n/a | 129053289 | CHEMBL4210682 | ~{N}-~{tert}-butyl-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-methyl-ethanamide | n/a | |
| 80 | P28482_ERZ | ERZ | n/a | 134129122 | CHEMBL4210146 | ~{N}-(1,5-dimethylpyrazol-4-yl)-5-methyl-pyrimidin-2-amine | n/a | |
| 81 | P28482_ESK | ESK | n/a | 134129123 | CHEMBL4205248 | 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-[(1~{S})-2-oxidanyl-1-phenyl-ethyl]ethanamide | n/a | |
| 82 | P28482_ESN | ESN | n/a | 129053491 | CHEMBL4212211 | (2~{R})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-[(1~{S})-1-(3-methylphenyl)-2-oxidanyl-ethyl]propanamide | n/a | |
| 83 | P28482_ESQ | ESQ | n/a | 129077836 | CHEMBL4213926 | 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2-(2-morpholin-4-ylethyl)-3~{H}-isoindol-1-one | n/a | |
| 84 | P28482_ESW | ESW | n/a | 129077798 | CHEMBL4206693 | 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-(2-phenylpropan-2-yl)ethanamide | n/a | |
| 85 | P28482_EU2 | EU2 | n/a | 129053223 | CHEMBL4204392 | 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2,3-dihydroisoindol-1-one | n/a | |
| 86 | P28482_EVK | EVK | DB13930 | 11719003 | CHEMBL3590106 | 4-[5-chloranyl-2-(propan-2-ylamino)pyridin-4-yl]-~{N}-[(1~{S})-1-(3-chlorophenyl)-2-oxidanyl-ethyl]-1~{H}-pyrrole-2-carboxamide | inhibitor | |
| 87 | P28482_EVQ | EVQ | n/a | 129077995 | CHEMBL4207147 | 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-[(1~{R})-1-(3-methoxyphenyl)ethyl]ethanamide | n/a | |
| 88 | P28482_F0E | F0E | n/a | 137349301 | n/a | cyclooctyl ~{N}-[3-[[4-[5-[[(3~{R})-1-[2-oxidanylidene-2-[4-(4-pyrimidin-2-ylphenyl)piperazin-1-yl]ethyl]pyrrolidin-3-yl]carbonylamino]-1~{H}-indazol-3-yl]pyridin-2-yl]carbonylamino]propyl]carbamate | n/a | |
| 89 | P28482_F0H | F0H | n/a | 135398132 | n/a | [(1~{R},4~{Z})-cyclooct-4-en-1-yl] ~{N}-[4-[4-[[4-[1-[(1~{S})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-2-oxidanylidene-pyridin-4-yl]pyrimidin-2-yl]amino]pyridin-2-yl]but-3-ynyl]carbamate | n/a | |
| 90 | P28482_F29 | F29 | n/a | 6419426 | CHEMBL199395 | 1-ALLYL-5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE | n/a | |
| 91 | P28482_F3Z | F3Z | n/a | 24866313 | CHEMBL3590107 | (3~{R})-1-[2-oxidanylidene-2-[4-(4-pyrimidin-2-ylphenyl)piperazin-1-yl]ethyl]-~{N}-(3-pyridin-4-yl-1~{H}-indazol-5-yl)pyrrolidine-3-carboxamide | n/a | |
| 92 | P28482_FRZ | FRZ | DB07794 | 11493598;53338808; | CHEMBL259551 | 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE | inhibitor | Ki(nM) = 310.0 IC50(nM) = 1200.0 Kd(nM) = 850.0 |
| 93 | P28482_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 94 | P28482_HOW | HOW | n/a | 1810216 | n/a | 1,2-oxazol-3-amine | n/a | |
| 95 | P28482_HRZ | HRZ | n/a | 8871;5280522; | CHEMBL662 | 1~{H}-pyridin-2-one | n/a | |
| 96 | P28482_HUH | HUH | n/a | 67516 | CHEMBL2148102 | 1~{H}-1,2,3-triazole | n/a | |
| 97 | P28482_HV2 | HV2 | n/a | 265635 | n/a | 1,1-bis(oxidanylidene)thietan-3-ol | n/a | |
| 98 | P28482_HVB | HVB | n/a | 6346752 | n/a | 1-azanylpropylideneazanium | n/a | |
| 99 | P28482_HVE | HVE | n/a | 137552759 | n/a | [1-(7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methylazanium | n/a | |
| 100 | P28482_HVK | HVK | n/a | 10439 | CHEMBL21619 | pyridin-2-amine | n/a | |
| 101 | P28482_HVQ | HVQ | n/a | 4328338 | n/a | thiophen-3-ylmethylazanium | n/a | |
| 102 | P28482_IMD | IMD | DB03366 | 444234;4434133;21983501; | n/a | IMIDAZOLE | n/a | |
| 103 | P28482_IPH | IPH | DB03255 | 996;20488062; | CHEMBL14060 | PHENOL | n/a | |
| 104 | P28482_KE8 | KE8 | DB18806 | 121408882 | CHEMBL4650285 | 6,6-dimethyl-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5-(2-morpholin-4-ylethyl)thieno[2,3-c]pyrrol-4-one | inhibitor | |
| 105 | P28482_LHZ | LHZ | n/a | 129116690 | CHEMBL4482864 | (6~{R})-7-[[3,4-bis(fluoranyl)phenyl]methyl]-6-(methoxymethyl)-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5,6-dihydroimidazo[1,2-a]pyrazin-8-one | n/a | |
| 106 | P28482_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 107 | P28482_MLA | MLA | DB02175 | 867;23511544; | CHEMBL7942 | MALONIC ACID | n/a | |
| 108 | P28482_N0V | N0V | n/a | 58946428 | CHEMBL3645227 | (3R)-N-[3-(2-cyclopropylpyridin-4-yl)-1H-indazol-5-yl]-3-(methoxymethyl)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]-3,6-dihydropyridin-1(2H)-yl}ethyl)pyrrolidine-3-carboxamide | n/a | |
| 109 | P28482_N29 | N29 | n/a | 3613419 | n/a | ~{N}-(5-methyl-1,2-oxazol-3-yl)propanamide | n/a | |
| 110 | P28482_N3O | N3O | n/a | 165111564 | n/a | ~{N}-(3-methyl-[1,2]oxazolo[5,4-b]pyridin-5-yl)propanamide | n/a | |
| 111 | P28482_N3X | N3X | n/a | 165111565 | n/a | ~{N}-[(1-methylindazol-6-yl)methyl]propanamide | n/a | |
| 112 | P28482_N4F | N4F | n/a | 131178689 | n/a | 1-(6,7-dihydro-4~{H}-[1,3]thiazolo[5,4-c]pyridin-5-yl)propan-1-one | n/a | |
| 113 | P28482_N4U | N4U | n/a | 126991142 | n/a | ~{N}-(2-methylpyrimidin-5-yl)propanamide | n/a | |
| 114 | P28482_N5U | N5U | n/a | 165111566 | n/a | 1-[(2~{R})-2-(3-methylimidazol-4-yl)piperidin-1-yl]propan-1-one | n/a | |
| 115 | P28482_N6K | N6K | n/a | 165111567 | n/a | ~{N}-(1~{H}-indazol-5-ylmethyl)ethanesulfonamide | n/a | |
| 116 | P28482_N6U | N6U | n/a | 23515122 | n/a | ~{N}-(1~{H}-pyrrolo[2,3-b]pyridin-4-yl)ethanesulfonamide | n/a | |
| 117 | P28482_N83 | N83 | n/a | 43616243 | CHEMBL3309327 | ~{N}-pyridin-3-ylprop-2-enamide | n/a | |
| 118 | P28482_N8L | N8L | n/a | 165111568 | n/a | 1-[(2~{S})-2-(5-methyl-3-pyridin-4-yl-1~{H}-pyrazol-4-yl)pyrrolidin-1-yl]propan-1-one | n/a | |
| 119 | P28482_N8U | N8U | n/a | 60650264 | n/a | ~{N}-(1~{H}-indazol-5-yl)ethanesulfonamide | n/a | |
| 120 | P28482_N96 | N96 | n/a | 90543536 | CHEMBL4522739 | ~{N}-(6,7-dihydro-4~{H}-pyrano[4,3-d][1,3]thiazol-2-yl)propanamide | n/a | |
| 121 | P28482_N9F | N9F | n/a | 139515589 | CHEMBL5199754 | ~{N}-(1~{H}-indazol-5-ylmethyl)ethanamide | n/a | |
| 122 | P28482_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 123 | P28482_NB3 | NB3 | n/a | 165111569 | n/a | ~{N}-[(1-methylindazol-3-yl)methyl]propanamide | n/a | |
| 124 | P28482_NH4 | NH4 | n/a | 223;16741146; | n/a | AMMONIUM ION | n/a | |
| 125 | P28482_NI | NI | n/a | 934 | n/a | NICKEL (II) ION | n/a | |
| 126 | P28482_NRA | NRA | n/a | 5281656 | CHEMBL187265 | norathyriol | n/a | |
| 127 | P28482_NX0 | NX0 | n/a | 165111570 | n/a | 1-(2,3-dihydropyrido[2,3-b][1,4]oxazin-1-yl)propan-1-one | n/a | |
| 128 | P28482_NXI | NXI | n/a | 165111571 | n/a | ~{N}-(1~{H}-indazol-5-ylmethyl)propanamide | n/a | |
| 129 | P28482_NY0 | NY0 | n/a | 8551010 | CHEMBL4784890 | 1-(3-oxidanyl-2~{H}-quinoxalin-1-yl)propan-1-one | n/a | |
| 130 | P28482_NYI | NYI | n/a | 10703275 | CHEMBL5171496 | 4-prop-2-enoyl-1,3-dihydroquinoxalin-2-one | n/a | |
| 131 | P28482_NYX | NYX | n/a | 165111572 | CHEMBL5187877 | 2-chloranyl-~{N}-(1~{H}-indazol-5-ylmethyl)ethanamide | n/a | |
| 132 | P28482_OZU | OZU | n/a | 5146703 | n/a | ~{N}-pyridin-3-ylpropanamide | n/a | |
| 133 | P28482_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 134 | P28482_PZO | PZO | DB02757 | 1048 | CHEMBL15967 | PYRAZOLE | n/a | |
| 135 | P28482_RYW | RYW | DB18900 | 129053037 | CHEMBL4847260 | (2~{R})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-[(1~{S})-1-(3-fluoranyl-5-methoxy-phenyl)-2-oxidanyl-ethyl]propanamide | n/a | |
| 136 | P28482_SB2 | SB2 | DB08521 | 9543416 | n/a | 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE | n/a | |
| 137 | P28482_SIN | SIN | DB00139 | 1110;21952380; | CHEMBL576 | SUCCINIC ACID | n/a | |
| 138 | P28482_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 139 | P28482_TAR | TAR | DB01694 | 439655 | CHEMBL1200861 | D(-)-TARTARIC ACID | n/a | |
| 140 | P28482_UMN | UMN | n/a | 156612916 | CHEMBL4868536 | 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-[(1~{S})-1-(hydroxymethyl)-2,3-dihydroinden-1-yl]ethanamide | n/a | |
| 141 | P28482_UNW | UNW | n/a | |||||
| 142 | P28482_UO5 | UO5 | n/a | 129077486 | CHEMBL4850133 | 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2-[2-oxidanylidene-2-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]-3~{H}-isoindol-1-one | n/a | |
| 143 | P28482_UOE | UOE | n/a | 129053409 | CHEMBL4856124 | (2~{R})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-[(1~{S})-1-[6-(4-methylpiperazin-1-yl)pyridin-2-yl]-2-oxidanyl-ethyl]propanamide | n/a | |
| 144 | P28482_UOH | UOH | n/a | 129053056 | CHEMBL4869800 | (2~{R})-2-[5-[5-chloranyl-2-[(2-methyl-1,2,3-triazol-4-yl)amino]pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-[(1~{S})-1-(3-fluoranyl-5-methoxy-phenyl)-2-oxidanyl-ethyl]propanamide | n/a | |
| 145 | P28482_UOW | UOW | n/a | 129053149 | CHEMBL4866448 | (2~{R})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-[(1~{S})-1-(2-methoxypyridin-4-yl)-2-oxidanyl-ethyl]propanamide | n/a | |
| 146 | P28482_Z48 | Z48 | n/a | 44480711 | CHEMBL565459 | N-[(1S)-2-hydroxy-1-phenylethyl]-4-[5-methyl-2-(phenylamino)pyrimidin-4-yl]-1H-pyrrole-2-carboxamide | n/a | |
| 147 | P28482_DB01169 | n/a | DB01169 | n/a | n/a | Arsenic trioxide | inducer | |
| 148 | P28482_OLO | OLO | DB02116 | 4592 | CHEMBL280074 | Olomoucine | n/a | IC50(nM) = 7000.0 |
| 149 | P28482_D11 | D11 | DB02482 | n/a | n/a | Phosphonothreonine | inhibitor | |
| 150 | P28482_PVB | PVB | DB02733 | 448991 | CHEMBL23254 | Purvalanol | inhibitor | |
| 151 | P28482_SB4 | SB4 | DB04338 | 5164 | CHEMBL274064 | SB220025 | inhibitor | IC50(nM) = 19000.0 |
| 152 | P28482_RRC | RRC | DB06195 | 160355 | CHEMBL14762 | Seliciclib | n/a | |
| 153 | P28482_DB06641 | n/a | DB06641 | n/a | n/a | Perifosine | n/a | |
| 154 | P28482_DB07788 | n/a | DB07788 | n/a | n/a | (3R,5Z,8S,9S,11E)-8,9,16-TRIHYDROXY-14-METHOXY-3-METHYL-3,4,9,10-TETRAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,7(8H)-DIONE | n/a | |
| 155 | P28482_HMY | HMY | DB07905 | 131676399 | n/a | Hypothemycin | n/a | |
| 156 | P28482_S91 | S91 | DB08513 | 24871491 | n/a | [4-({5-(AMINOCARBONYL)-4-[(3-METHYLPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETIC ACID | n/a | |
| 157 | P28482_DB08521 | n/a | DB08521 | n/a | n/a | 4-[4-(4-Fluorophenyl)-2-[4-[(R)-methylsulfinyl]phenyl]-1H-imidazol-5-yl]pyridine | n/a |