Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
P29375 KDM5A_HUMAN
Gene name: KDM5A
Protein name: Lysine-specific demethylase 5A

List of molecules and drugs that interact with protein P29375

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 P29375_50P 50P n/a n/a CHEMBL4454253 7-oxo-5-phenyl-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile n/a
2 P29375_6E7 6E7 n/a 45378188 CHEMBL2169917 4'-[(2-phenylethyl)carbamoyl][2,2'-bipyridine]-4-carboxylic acid n/a
3 P29375_6E8 6E8 n/a n/a CHEMBL4468119 5-methyl-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile n/a
4 P29375_6EB 6EB n/a 118871298;136959977; CHEMBL3787534 8-(1-methyl-1H-imidazol-4-yl)-2-(4,4,4-trifluorobutoxy)pyrido[3,4-d]pyrimidin-4-ol n/a
5 P29375_6ED 6ED n/a 90216621 n/a 3-({1-[2-(4,4-difluoropiperidin-1-yl)ethyl]-5-fluoro-1H-indazol-3-yl}amino)pyridine-4-carboxylic acid n/a
6 P29375_6EN 6EN n/a 76283751 CHEMBL5277662 3-[(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)amino]pyridine-4-carboxylic acid n/a
7 P29375_6EO 6EO n/a 64393976 CHEMBL5278205 3-{[(4-chlorophenyl)acetyl]amino}pyridine-4-carboxylic acid n/a
8 P29375_6EP 6EP n/a 74766595 CHEMBL3786952 2-{5-[(4-chloro-2-methylphenyl)methoxy]-1H-pyrazol-1-yl}pyridine-4-carboxylic acid n/a
9 P29375_6QN 6QN n/a 121488114 CHEMBL4441819 ~{N}-ethyl-4-oxidanyl-2-oxidanylidene-1~{H}-1,7-naphthyridine-3-carboxamide n/a
10 P29375_90S 90S n/a 126961719 n/a [(3S)-3-(4-bromo-1H-pyrazol-1-yl)pyrrolidin-1-yl][3-(propan-2-yl)-1H-pyrazol-5-yl]methanone n/a
11 P29375_90V 90V n/a 119081409 CHEMBL4088737 N-{(3R)-1-[3-(propan-2-yl)-1H-pyrazole-5-carbonyl]pyrrolidin-3-yl}cyclopropanecarboxamide n/a
12 P29375_AKG AKG DB08845 51;156274072; CHEMBL1686 2-OXOGLUTARIC ACID n/a
13 P29375_DKP DKP n/a 132472257 n/a 2-[(R)-(2-chlorophenyl)(propoxy)methyl]-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid n/a
14 P29375_DKS DKS n/a 132472259 n/a 2-{(S)-(2-chlorophenyl)[2-(4,4-difluoropiperidin-1-yl)ethoxy]methyl}-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid n/a
15 P29375_DKV DKV n/a 132472260 n/a 2-{(S)-(2-chlorophenyl)[(4,4-difluorocyclohexyl)methoxy]methyl}-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid n/a
16 P29375_DLJ DLJ n/a 132472261 n/a 2-[(S)-(2-chlorophenyl){2-[(2R)-1-methylpyrrolidin-2-yl]ethoxy}methyl]-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid n/a
17 P29375_DMS DMS DB01093 679 CHEMBL504 DIMETHYL SULFOXIDE n/a
18 P29375_DNV DNV n/a 132472262 n/a 2-{(S)-(2-chlorophenyl)[2-(1-methyl-1H-imidazol-2-yl)ethoxy]methyl}-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid n/a
19 P29375_DNY DNY n/a 132472264 n/a 2-{(S)-(2-chlorophenyl)[3-(piperidin-1-yl)propoxy]methyl}-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid n/a
20 P29375_DO1 DO1 n/a 132472263 CHEMBL4062359 2-{(R)-(2-chlorophenyl)[2-(piperidin-1-yl)ethoxy]methyl}-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid n/a
21 P29375_DQG DQG n/a 132472258 CHEMBL4096760 2-{(S)-(2-chlorophenyl)[2-(piperidin-1-yl)ethoxy]methyl}-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid n/a
22 P29375_DQJ DQJ n/a 129606887 CHEMBL4067490 N-{(3S)-1-[5-(propan-2-yl)-1H-pyrazole-3-carbonyl]pyrrolidin-3-yl}cyclopropanecarboxamide n/a
23 P29375_DQS DQS n/a n/a CHEMBL3785583 5-(1-tert-butyl-1H-pyrazol-4-yl)-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile n/a
24 P29375_EDO EDO n/a 174 CHEMBL457299 1,2-ETHANEDIOL n/a
25 P29375_GOL GOL DB09462 753 CHEMBL692 GLYCEROL n/a
26 P29375_H5Y H5Y n/a 138393319 n/a 2-[4-{[2-(dimethylamino)ethyl](ethyl)carbamoyl}-5-(4-methoxyphenyl)-1H-pyrazol-1-yl]pyridine-4-carboxylic acid n/a
27 P29375_H61 H61 n/a 133053887 n/a 2-{1-[2-(piperidin-1-yl)ethyl]-1H-benzimidazol-2-yl}thieno[3,2-b]pyridine-7-carboxylic acid n/a
28 P29375_H67 H67 n/a 138393320 n/a 2-[5-([1,1'-biphenyl]-3-yl)-4-{(1S)-1-[2-(piperidin-1-yl)ethoxy]ethyl}-1H-pyrazol-1-yl]pyridine-4-carboxylic acid n/a
29 P29375_H6A H6A n/a 138393321 n/a 2-(5-phenyl-4-{(R)-phenyl[2-(piperidin-1-yl)ethoxy]methyl}-1H-pyrazol-1-yl)pyridine-4-carboxylic acid n/a
30 P29375_H6G H6G n/a 133053816 CHEMBL4283844 N-[6-(4-acryloyl-1,4-diazepan-1-yl)-2-(pyridin-2-yl)pyrimidin-4-yl]-beta-alanine n/a
31 P29375_H6J H6J n/a 137349487 CHEMBL4294426 N-{6-[4-(ethenylsulfonyl)-1,4-diazepan-1-yl]-2-(pyridin-2-yl)pyrimidin-4-yl}-beta-alanine n/a
32 P29375_H6M H6M n/a 138753233 n/a N-{6-[4-(hydroxyacetyl)-1,4-diazepan-1-yl]-2-(pyridin-2-yl)pyrimidin-4-yl}-beta-alanine n/a
33 P29375_H6S H6S n/a 134828059 n/a 2-[(R)-(2-chlorophenyl){2-[(2S)-1-methylpyrrolidin-2-yl]ethoxy}methyl]thieno[3,2-b]pyridine-7-carboxylic acid n/a
34 P29375_H6T H6T n/a 134828060 n/a 2-[(S)-(2-chlorophenyl){2-[(2S)-1-methylpyrrolidin-2-yl]ethoxy}methyl]thieno[3,2-b]pyridine-7-carboxylic acid n/a
35 P29375_H6V H6V n/a 134828062 n/a 2-{(R)-(3-aminophenyl)[2-(piperidin-1-yl)ethoxy]methyl}thieno[3,2-b]pyridine-7-carboxylic acid n/a
36 P29375_H74 H74 n/a 137349490 n/a 2-{(R)-[3-(acryloylamino)phenyl][2-(piperidin-1-yl)ethoxy]methyl}thieno[3,2-b]pyridine-7-carboxylic acid n/a
37 P29375_H77 H77 n/a 134828063 n/a 2-{(R)-(3-{[(2E)-4-(dimethylamino)but-2-enoyl]amino}phenyl)[2-(piperidin-1-yl)ethoxy]methyl}thieno[3,2-b]pyridine-7-carboxylic acid n/a
38 P29375_HZM HZM n/a 137349539 n/a 2-{(S)-(3-{[4-(dimethylamino)butanoyl]amino}phenyl)[2-(piperidin-1-yl)ethoxy]methyl}thieno[3,2-b]pyridine-7-carboxylic acid n/a
39 P29375_HZV HZV n/a 134828064 n/a 2-{(R)-(3-{[4-(dimethylamino)butanoyl]amino}phenyl)[2-(piperidin-1-yl)ethoxy]methyl}thieno[3,2-b]pyridine-7-carboxylic acid n/a
40 P29375_K0I K0I n/a 56963315 CHEMBL3188597 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid n/a
41 P29375_LQT LQT n/a 91810435 CHEMBL4078388 2-[[[2-[2-(dimethylamino)ethyl-ethyl-amino]-2-oxidanylidene-ethyl]amino]methyl]pyridine-4-carboxamide n/a
42 P29375_MMK MMK n/a 137349755 n/a 2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid n/a
43 P29375_MN MN n/a 27854 n/a MANGANESE (II) ION n/a
44 P29375_NI NI n/a 934 n/a NICKEL (II) ION n/a
45 P29375_SO4 SO4 DB14546 1117 n/a SULFATE ION n/a
46 P29375_ZN ZN n/a 32051 CHEMBL1236970 ZINC ION n/a