Gene name: CASP1
Protein name: Caspase-1 (CASP-1) (EC
List of molecules and drugs that interact with protein P29466
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P29466_158 | 158 | n/a | 5287427 | n/a | 3-(2-MERCAPTO-ACETYLAMINO)-4-OXO-PENTANOIC ACID | n/a | |
| 2 | P29466_3NS | 3NS | n/a | 72200264 | n/a | (3S)-4-hydroxy-3-{[(2S)-4-{[2-(2-methyl-1H-benzimidazol-1-yl)ethyl]amino}-2-(1-methylethyl)-4-oxobutanoyl]amino}butanoic acid | n/a | |
| 3 | P29466_4QB | 4QB | n/a | 5287520 | n/a | 3-{2-ETHYL-6-[4-(QUINOXALIN-2-YLAMINO)-BENZOYLAMINO]-HEXANOYLAMINO}-4-OXO-BUTYRIC ACID | n/a | |
| 4 | P29466_5PH | 5PH | n/a | 5287535 | n/a | 5-[5-(1-CARBOXYMETHYL-2-OXO-PROPYLCARBAMOYL)-5-PHENYL-PENTYLSULFAMOYL]-2-HYDROXY-BENZOIC ACID | n/a | |
| 5 | P29466_BTH | BTH | n/a | 5287849 | n/a | 4-OXO-3-{6-[4-(QUINOXALIN-2-YLAMINO)-BENZOYLAMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-PENTANOIC ACID | n/a | |
| 6 | P29466_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 7 | P29466_CVE | CVE | n/a | 137349133 | n/a | (3~{S})-3-[[(2~{R})-2-[3-methyl-2,6-bis(oxidanylidene)-5-[[4-(quinoxalin-2-ylamino)phenyl]carbonylamino]pyrimidin-1-yl]propanoyl]amino]-4-oxidanyl-butanoic acid | n/a | |
| 8 | P29466_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 9 | P29466_F1G | F1G | DB07733 | 6852193 | n/a | 1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE | n/a | |
| 10 | P29466_HQC | HQC | DB07916 | 5288581 | n/a | 3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID | n/a | |
| 11 | P29466_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 12 | P29466_MLI | MLI | DB02201 | 9084 | n/a | MALONATE ION | n/a | |
| 13 | P29466_MNO | MNO | n/a | 5288820 | n/a | (3S)-N-METHANESULFONYL-3-({1-[N-(2-NAPHTOYL)-L-VALYL]-L-PROLYL}AMINO)-4-OXOBUTANAMIDE | n/a | |
| 14 | P29466_N7N | N7N | n/a | 137349792 | n/a | (3~{S})-3-[[(3~{S},6~{S},10~{a}~{S})-6-(isoquinolin-1-ylcarbonylamino)-5-oxidanylidene-2,3,6,7,8,9,10,10~{a}-octahydro-1~{H}-pyrrolo[1,2-a]azocin-3-yl]carbonylamino]-4-oxidanyl-butanoic acid | n/a | |
| 15 | P29466_OQB | OQB | n/a | 5289080 | CHEMBL202160 | 4-OXO-3-[(6-{[4-(QUINOXALIN-2-YLAMINO)-BENZOYLAMINO]-METHYL}-PYRIDINE-3-CARBONYL)-AMINO]-BUTYRIC ACID | n/a | |
| 16 | P29466_P7S | P7S | n/a | 11443029 | CHEMBL4802237 | N-(4-amino-3-chlorobenzene-1-carbonyl)-3-methyl-L-valyl-N-[(2S)-1-carboxy-3-oxopropan-2-yl]-L-prolinamide | n/a | |
| 17 | P29466_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 18 | P29466_Q2Y | Q2Y | n/a | 49867553 | n/a | 4-OXO-3-[2-(5-{[4-(QUINOXALIN-2-YLAMINO)-BENZOYLAMINO]-METHYL}-THIOPHEN-2-YL)-ACETYLAMINO]-PENTANOIC ACID | n/a | |
| 19 | P29466_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 20 | P29466_WE0 | WE0 | n/a | n/a | n/a | (3~{S})-3-[[(3~{S})-2-[(2~{S})-3-methyl-2-(naphthalen-2-ylcarbonylamino)butanoyl]-4-oxidanyl-2-azabicyclo[2.2.2]octan-3-yl]carbonylamino]-4-oxidanyl-butanoic acid | n/a | |
| 21 | P29466_YBH | YBH | n/a | 5289610 | n/a | 4-OXO-3-{6-[4-(QUINOXALIN-2-YLOXY)-BENZOYLAMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-BUTYRIC ACID | n/a | |
| 22 | P29466_AIN | AIN | DB00945 | 2244 | CHEMBL25 | Acetylsalicylic acid | inhibitor | |
| 23 | P29466_MIY | MIY | DB01017 | n/a | CHEMBL1434 | Minocycline | negative modulator | |
| 24 | P29466_DB04875 | n/a | DB04875 | n/a | n/a | Pralnacasan | modulator | IC50(nM) = 2.0 |
| 25 | P29466_DB05408 | n/a | DB05408 | n/a | n/a | Emricasan | n/a | |
| 26 | P29466_DB07744 | n/a | DB07744 | n/a | n/a | Z-Val-Ala-Asp fluoromethyl ketone | n/a |