Gene name: MAT2A
Protein name: S-adenosylmethionine synthase isoform
List of molecules and drugs that interact with protein P31153
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P31153_1PE | 1PE | n/a | 62551 | CHEMBL1229766 | PENTAETHYLENE GLYCOL | n/a | |
| 2 | P31153_2PN | 2PN | n/a | 122874 | CHEMBL265450 | IMIDODIPHOSPHORIC ACID | n/a | |
| 3 | P31153_7U2 | 7U2 | n/a | 97507059 | n/a | (3'R)-N-(cyclopropylmethyl)-1'-[(2-fluorophenyl)methyl]-4-methyl-5H,7H-spiro[pyrano[4,3-d]pyrimidine-8,3'-pyrrolidin]-2-amine | n/a | |
| 4 | P31153_7UB | 7UB | n/a | 162679121 | n/a | (3'R)-2-[(cyclopropylmethyl)amino]-6-(4-methoxyphenyl)-1'-[(1H-pyrazol-5-yl)methyl]-5,6-dihydro-7H-spiro[pyrido[4,3-d]pyrimidine-8,3'-pyrrolidin]-7-one | n/a | |
| 5 | P31153_7UI | 7UI | n/a | 139552098 | CHEMBL5170690 | 8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-[2,2,2-tris(fluoranyl)ethylamino]pyrido[4,3-d]pyrimidin-7-ol | n/a | |
| 6 | P31153_7UN | 7UN | n/a | 139551841 | CHEMBL5178902 | (8R)-8-(4-chlorophenyl)-6-(2-methyl-2H-indazol-5-yl)-2-[(2,2,2-trifluoroethyl)amino]-5,8-dihydropyrido[4,3-d]pyrimidin-7(6H)-one | n/a | |
| 7 | P31153_8AJ | 8AJ | n/a | 12612431 | CHEMBL337420 | 2-(7-chloro-5-phenyl[1,2,4]triazolo[4,3-a]quinolin-1-yl)-N,N-dimethylethan-1-amine | n/a | |
| 8 | P31153_ABA | ABA | n/a | 80283;6971252; | CHEMBL1230782 | ALPHA-AMINOBUTYRIC ACID | n/a | |
| 9 | P31153_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 10 | P31153_ADN | ADN | DB00640 | 60961 | CHEMBL477 | ADENOSINE | n/a | |
| 11 | P31153_ALA | ALA | DB00160 | 5950;7311724; | CHEMBL279597 | ALANINE | n/a | |
| 12 | P31153_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 13 | P31153_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 14 | P31153_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 15 | P31153_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 16 | P31153_IMD | IMD | DB03366 | 444234;4434133;21983501; | n/a | IMIDAZOLE | n/a | |
| 17 | P31153_J41 | J41 | n/a | n/a | CHEMBL4859703 | 5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one | n/a | |
| 18 | P31153_J4A | J4A | n/a | n/a | CHEMBL4560666 | 6-(4-hydroxyphenyl)-5-methyl-2-phenyl-3-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one | n/a | |
| 19 | P31153_K | K | n/a | 813 | CHEMBL1233793 | POTASSIUM ION | n/a | |
| 20 | P31153_MED | MED | DB02893 | 84815;6992109; | CHEMBL1234268 | D-METHIONINE | n/a | |
| 21 | P31153_MET | MET | DB00134 | 6137;6992087; | CHEMBL42336 | METHIONINE | n/a | |
| 22 | P31153_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 23 | P31153_MGF | MGF | n/a | 447728;5496785; | n/a | TRIFLUOROMAGNESATE | n/a | |
| 24 | P31153_MLA | MLA | DB02175 | 867;23511544; | CHEMBL7942 | MALONIC ACID | n/a | |
| 25 | P31153_MPD | MPD | DB03564 | 5288834 | n/a | (4S)-2-METHYL-2,4-PENTANEDIOL | n/a | |
| 26 | P31153_MTA | MTA | DB02282 | 439176 | CHEMBL277041 | 5'-DEOXY-5'-METHYLTHIOADENOSINE | n/a | |
| 27 | P31153_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 28 | P31153_P3G | P3G | DB02343 | 78057 | n/a | 3,6,9,12,15-PENTAOXAHEPTADECANE | n/a | |
| 29 | P31153_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 30 | P31153_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 31 | P31153_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 32 | P31153_POP | POP | n/a | 4995;18628280;57345951; | n/a | PYROPHOSPHATE 2- | n/a | |
| 33 | P31153_PPK | PPK | DB03075 | 447781 | n/a | (DIPHOSPHONO)AMINOPHOSPHONIC ACID | n/a | |
| 34 | P31153_PPV | PPV | DB04160 | 1023;21961011; | CHEMBL1160571 | PYROPHOSPHATE | n/a | |
| 35 | P31153_S7M | S7M | n/a | n/a | n/a | [(3S)-3-amino-3-carboxypropyl]{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}ethyls ulfonium | n/a | |
| 36 | P31153_SAM | SAM | DB00118 | n/a | CHEMBL1235831 | S-ADENOSYLMETHIONINE | cofactor | |
| 37 | P31153_TNW | TNW | n/a | 155899145 | CHEMBL5075691 | 7-chloranyl-4-(dimethylamino)-1-(3-methylphenyl)quinazolin-2-one | n/a | |
| 38 | P31153_TNZ | TNZ | n/a | 742338 | CHEMBL5078655 | 6-chloranyl-2-methoxy-4-phenyl-quinazoline | n/a | |
| 39 | P31153_TO5 | TO5 | n/a | 155899146 | CHEMBL5078692 | 7-chloranyl-4-(dimethylamino)-1-pyridin-3-yl-quinazolin-2-one | n/a | |
| 40 | P31153_TO8 | TO8 | n/a | 133054303 | CHEMBL5090541 | 7-chloranyl-4-(dimethylamino)-1~{H}-quinazolin-2-one | n/a | |
| 41 | P31153_TOW | TOW | n/a | 155899144 | CHEMBL5086019 | 7-chloranyl-4-(dimethylamino)-1-(2-hydroxyethyl)quinazolin-2-one | n/a | |
| 42 | P31153_TQB | TQB | n/a | 150703860 | CHEMBL5090022 | 7-chloranyl-4-(dimethylamino)-1-phenyl-quinazolin-2-one | n/a | |
| 43 | P31153_TQE | TQE | n/a | 23338138 | CHEMBL5078947 | 4-(dimethylamino)-6-ethoxy-1~{H}-1,3,5-triazin-2-one | n/a | |
| 44 | P31153_TRS | TRS | DB03754 | 3777159;88088752;152743085; | n/a | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 45 | P31153_U4P | U4P | n/a | 444437 | CHEMBL3250647 | 5'-deoxyuridine | n/a | |
| 46 | P31153_UM6 | UM6 | n/a | 150331522 | CHEMBL5427280 | 7-chloranyl-4-[(3R)-3-fluoranylpyrrolidin-1-yl]-1-phenyl-quinazolin-2-one | n/a | |
| 47 | P31153_VUO | VUO | DB13343 | 72139 | CHEMBL442687 | 6-oxidanyl-1,3-benzoxathiol-2-one | n/a | |
| 48 | P31153_WBG | WBG | n/a | n/a | CHEMBL4573938 | 3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenyl-5-[(pyridin-2-yl)amino]pyrazolo[1,5-a]pyrimidin-7(4H)-one | n/a | |
| 49 | P31153_WBM | WBM | n/a | n/a | CHEMBL4875209 | 2,3-diphenyl-5-[(1H-pyrazol-3-yl)amino]pyrazolo[1,5-a]pyrimidin-7(4H)-one | n/a | |
| 50 | P31153_WBS | WBS | n/a | n/a | CHEMBL4514699 | 6-(4-hydroxyphenyl)-2,3-diphenyl-5-[(1H-pyrazol-3-yl)amino]pyrazolo[1,5-a]pyrimidin-7(4H)-one | n/a | |
| 51 | P31153_WIV | WIV | n/a | 168475497 | CHEMBL5400313 | 6-cyclopropyl-~{N}-(2-methylindazol-5-yl)-1-propan-2-yl-pyrazolo[3,4-b]pyridine-4-carboxamide | n/a | |
| 52 | P31153_WJL | WJL | n/a | 71943485 | CHEMBL5433543 | 6-cyclopropyl-~{N}-(1~{H}-indazol-5-yl)-1-propan-2-yl-pyrazolo[3,4-b]pyridine-4-carboxamide | n/a | |
| 53 | P31153_WK5 | WK5 | n/a | n/a | n/a | 8-methoxy-1-(4-methoxyphenyl)-3-methyl-2-oxidanyl-[1]benzofuro[3,2-c]pyridine | n/a | |
| 54 | P31153_XE1 | XE1 | n/a | n/a | n/a | N,N'-(dihydroxy-lambda~5~-phosphanediyl)bis(phosphoramidic acid) | n/a | |
| 55 | P31153_YQP | YQP | n/a | 162677699 | n/a | (2~{S})-2-azanyl-4-[[(2~{S},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl-methyl-$l^{3}-sulfanyl]butanoic acid | n/a | |
| 56 | P31153_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 57 | P31153_DB00118 | n/a | DB00118 | n/a | n/a | Ademetionine | cofactor |