Gene name: acrB
Protein name: Multidrug efflux pump
List of molecules and drugs that interact with protein P31224
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P31224_1K8 | 1K8 | n/a | 153987774 | n/a | 3-chloranyl-2-piperazin-1-yl-quinoline | n/a | |
| 2 | P31224_1KE | 1KE | n/a | 162371033 | n/a | 1-(3-chloranyl-5-iodanyl-pyridin-2-yl)piperazine | n/a | |
| 3 | P31224_1PE | 1PE | n/a | 62551 | CHEMBL1229766 | PENTAETHYLENE GLYCOL | n/a | |
| 4 | P31224_3YI | 3YI | n/a | 6438444 | CHEMBL3323549 | (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-8-formyl-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptam ethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate | n/a | |
| 5 | P31224_5QE | 5QE | n/a | 118987006 | n/a | ~{N}-[4-[2-[[5-cyano-8-[(2~{S},6~{R})-2,6-dimethylmorpholin-4-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridin-6-yl]sulfanyl]ethyl]phenyl]ethanamide | n/a | |
| 6 | P31224_5QF | 5QF | n/a | 86281621 | CHEMBL3400632 | 6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile | n/a | |
| 7 | P31224_5QG | 5QG | n/a | 1289417 | CHEMBL3401827 | 3,3-dimethyl-8-morpholin-4-yl-6-(2-phenylethylsulfanyl)-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile | n/a | |
| 8 | P31224_8K6 | 8K6 | n/a | 11635 | n/a | Octadecane | n/a | |
| 9 | P31224_AIC | AIC | DB00415 | 6249;7048611; | CHEMBL174 | (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID | n/a | |
| 10 | P31224_C14 | C14 | n/a | 12389 | CHEMBL135488 | TETRADECANE | n/a | |
| 11 | P31224_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 12 | P31224_CPF | CPF | DB00537 | 2764;4011971; | CHEMBL8 | 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID | n/a | |
| 13 | P31224_D10 | D10 | n/a | 15600 | CHEMBL134537 | DECANE | n/a | |
| 14 | P31224_D12 | D12 | n/a | 8182 | CHEMBL30959 | DODECANE | n/a | |
| 15 | P31224_DD9 | DD9 | n/a | 8141 | CHEMBL335900 | nonane | n/a | |
| 16 | P31224_DDQ | DDQ | DB02613 | 62452 | CHEMBL1232157 | DECYLAMINE-N,N-DIMETHYL-N-OXIDE | n/a | |
| 17 | P31224_DDR | DDR | n/a | 162916 | n/a | (2S)-3-hydroxypropane-1,2-diyl didecanoate | n/a | |
| 18 | P31224_DEQ | DEQ | DB04209 | 2993 | CHEMBL333826 | DEQUALINIUM | n/a | |
| 19 | P31224_DM2 | DM2 | DB00997 | 31703 | CHEMBL53463 | DOXORUBICIN | n/a | |
| 20 | P31224_DXC | DXC | DB03619 | 222528 | CHEMBL406393 | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID | n/a | |
| 21 | P31224_DXT | DXT | DB00254 | n/a | CHEMBL1433 | (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE | n/a | |
| 22 | P31224_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 23 | P31224_ERY | ERY | DB00199 | 12560 | CHEMBL532 | ERYTHROMYCIN A | n/a | |
| 24 | P31224_ET | ET | DB17031 | 3624;101633772; | CHEMBL48166 | ETHIDIUM | n/a | |
| 25 | P31224_ETE | ETE | DB04332 | 90263 | CHEMBL1232586 | 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL | n/a | |
| 26 | P31224_FLC | FLC | n/a | 31348 | n/a | CITRATE ANION | n/a | |
| 27 | P31224_FUA | FUA | DB02703 | 3000226 | CHEMBL374975 | FUSIDIC ACID | n/a | |
| 28 | P31224_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 29 | P31224_HEX | HEX | n/a | 8058 | CHEMBL15939 | HEXANE | n/a | |
| 30 | P31224_LFX | LFX | DB01137 | 149096;6956357; | CHEMBL33 | (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid | n/a | |
| 31 | P31224_LMT | LMT | n/a | 114880 | CHEMBL1234047 | DODECYL-BETA-D-MALTOSIDE | n/a | |
| 32 | P31224_LMU | LMU | DB03279 | 445456 | CHEMBL1234048 | DODECYL-ALPHA-D-MALTOSIDE | n/a | |
| 33 | P31224_LNK | LNK | n/a | 8003 | CHEMBL16102 | PENTANE | n/a | |
| 34 | P31224_LPX | LPX | n/a | 25229539;72199749; | n/a | (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate | n/a | |
| 35 | P31224_MBX | MBX | n/a | 118987007 | n/a | ~{N}-[4-[2-[[5-cyano-8-[(2~{S},6~{S})-2,6-dimethylmorpholin-4-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridin-6-yl]sulfanyl]ethyl]phenyl]prop-2-enamide | n/a | |
| 36 | P31224_MC2 | MC2 | n/a | 443301 | CHEMBL56252 | N2-(L-PHENYLALANYL)-N1-(NAPHTHALENYL)-L-ARIGNINAMIDE | n/a | |
| 37 | P31224_MIY | MIY | DB01017 | n/a | CHEMBL1434 | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE | n/a | |
| 38 | P31224_MYS | MYS | n/a | 12391 | CHEMBL1234557 | PENTADECANE | n/a | |
| 39 | P31224_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 40 | P31224_NFN | NFN | DB00607 | 5289006 | n/a | 6-[[(2-ETHOXY-1-NAPHTHALENYL)CARBONYL]AMINO]-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLATE | n/a | |
| 41 | P31224_NI | NI | n/a | 934 | n/a | NICKEL (II) ION | n/a | |
| 42 | P31224_OCT | OCT | n/a | 356 | CHEMBL134886 | N-OCTANE | n/a | |
| 43 | P31224_P3G | P3G | DB02343 | 78057 | n/a | 3,6,9,12,15-PENTAOXAHEPTADECANE | n/a | |
| 44 | P31224_P6G | P6G | n/a | 17472 | CHEMBL1235082 | HEXAETHYLENE GLYCOL | n/a | |
| 45 | P31224_P9D | P9D | n/a | 17757337 | CHEMBL394052 | [{2-[({[(3R)-1-{8-[(4-tert-butyl-1,3-thiazol-2-yl)carbamoyl]-4-oxo-3-[(E)-2-(1H-tetrazol-5-yl)ethenyl]-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidin-3-yl]oxy}carbonyl)amino]ethyl}(dimethyl)ammonio]acetate | n/a | |
| 46 | P31224_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 47 | P31224_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 48 | P31224_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 49 | P31224_PTY | PTY | n/a | 446872 | n/a | PHOSPHATIDYLETHANOLAMINE | n/a | |
| 50 | P31224_PUY | PUY | DB08437 | 439530 | CHEMBL469912 | PUROMYCIN | n/a | |
| 51 | P31224_R16 | R16 | n/a | 11006 | CHEMBL134994 | HEXADECANE | n/a | |
| 52 | P31224_RBT | RBT | DB00615 | 6323490 | CHEMBL444633 | RIFABUTIN | n/a | |
| 53 | P31224_RFP | RFP | DB01045 | 135398735;136262914; | CHEMBL374478 | RIFAMPICIN | n/a | |
| 54 | P31224_RHQ | RHQ | DB03825 | 5464057 | n/a | RHODAMINE 6G | n/a | |
| 55 | P31224_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 56 | P31224_UND | UND | n/a | 14257 | CHEMBL132474 | UNDECANE | n/a | |
| 57 | P31224_XPE | XPE | n/a | 79689 | n/a | 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL | n/a | |
| 58 | P31224_ZLD | ZLD | DB00601 | 441401 | CHEMBL126 | N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide | n/a |