Gene name: SLC5A2
Protein name: Sodium/glucose cotransporter 2
List of molecules and drugs that interact with protein P31639
# | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
---|---|---|---|---|---|---|---|---|
1 | P31639_7R3 | 7R3 | DB09038 | 11949646 | CHEMBL2107830 | (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | inhibitor | IC50(nM) = 3.1 EC50(nM) = 3.0 |
2 | P31639_GYP | GYP | n/a | 64947 | CHEMBL131853 | methyl alpha-D-glucopyranoside | n/a | |
3 | P31639_KZ3 | KZ3 | n/a | 24759836 | CHEMBL1782369 | (2R,3R,4S,5S,6R)-2-[3-[(4-cyclopropylphenyl)methyl]-4-fluoranyl-indol-1-yl]-6-(hydroxymethyl)oxane-3,4,5-triol | n/a | |
4 | P31639_L3R | L3R | DB08907 | 24812758 | CHEMBL2048484 | (2~{S},3~{R},4~{R},5~{S},6~{R})-2-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methyl-phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | inhibitor | IC50(nM) = 2.2 EC50(nM) = 2.2 |
5 | P31639_LE6 | LE6 | DB06292 | 9887712 | CHEMBL429910 | (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | antagonist | IC50(nM) = 0.49 EC50(nM) = 1.1 |
6 | P31639_LFL | LFL | DB12713 | 24831714 | CHEMBL3039507 | (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[(4-ethoxyphenyl)methyl]phenyl]-6-methylsulfanyl-oxane-3,4,5-triol | inhibitor | |
7 | P31639_LN9 | LN9 | DB16771 | 6072 | CHEMBL245067 | 1-[2-[(2S,3R,4S,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,6-bis(oxidanyl)phenyl]-3-(4-hydroxyphenyl)propan-1-one | n/a | |
8 | P31639_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
9 | P31639_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
10 | P31639_PLM | PLM | DB03796 | 985;135369651; | CHEMBL82293 | PALMITIC ACID | n/a | |
11 | P31639_DB06292 | n/a | DB06292 | n/a | n/a | Dapagliflozin | antagonist | IC50(nM) = 0.49 EC50(nM) = 1.1 |
12 | P31639_DB08907 | n/a | DB08907 | n/a | n/a | Canagliflozin | inhibitor | IC50(nM) = 2.2 EC50(nM) = 2.2 |
13 | P31639_DB11827 | n/a | DB11827 | n/a | n/a | Ertugliflozin | inhibitor | |
14 | P31639_DB12713 | n/a | DB12713 | n/a | n/a | Sotagliflozin | inhibitor |