P31639 SC5A2_HUMAN
Gene name: SLC5A2
Protein name: Sodium/glucose cotransporter 2

List of molecules and drugs that interact with protein P31639

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 P31639_7R3 7R3 DB09038 11949646 CHEMBL2107830 (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol inhibitor IC50(nM) = 3.1
EC50(nM) = 3.0
2 P31639_GYP GYP n/a 64947 CHEMBL131853 methyl alpha-D-glucopyranoside n/a
3 P31639_KZ3 KZ3 n/a 24759836 CHEMBL1782369 (2R,3R,4S,5S,6R)-2-[3-[(4-cyclopropylphenyl)methyl]-4-fluoranyl-indol-1-yl]-6-(hydroxymethyl)oxane-3,4,5-triol n/a
4 P31639_L3R L3R DB08907 24812758 CHEMBL2048484 (2~{S},3~{R},4~{R},5~{S},6~{R})-2-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methyl-phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol inhibitor IC50(nM) = 2.2
EC50(nM) = 2.2
5 P31639_LE6 LE6 DB06292 9887712 CHEMBL429910 (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol antagonist IC50(nM) = 0.49
EC50(nM) = 1.1
6 P31639_LFL LFL DB12713 24831714 CHEMBL3039507 (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[(4-ethoxyphenyl)methyl]phenyl]-6-methylsulfanyl-oxane-3,4,5-triol inhibitor
7 P31639_LN9 LN9 DB16771 6072 CHEMBL245067 1-[2-[(2S,3R,4S,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,6-bis(oxidanyl)phenyl]-3-(4-hydroxyphenyl)propan-1-one n/a
8 P31639_NA NA n/a 923 n/a SODIUM ION n/a
9 P31639_NAG NAG DB00141 24139 CHEMBL447878 2-acetamido-2-deoxy-beta-D-glucopyranose n/a
10 P31639_PLM PLM DB03796 985;135369651; CHEMBL82293 PALMITIC ACID n/a
11 P31639_DB06292 n/a DB06292 n/a n/a Dapagliflozin antagonist IC50(nM) = 0.49
EC50(nM) = 1.1
12 P31639_DB08907 n/a DB08907 n/a n/a Canagliflozin inhibitor IC50(nM) = 2.2
EC50(nM) = 2.2
13 P31639_DB11827 n/a DB11827 n/a n/a Ertugliflozin inhibitor
14 P31639_DB12713 n/a DB12713 n/a n/a Sotagliflozin inhibitor