Gene name: GABRA5
Protein name: Gamma-aminobutyric acid receptor
List of molecules and drugs that interact with protein P31644
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P31644_ABU | ABU | DB02530 | 119;6992099; | CHEMBL96 | GAMMA-AMINO-BUTANOIC ACID | inhibitor | Ki(nM) = 8.7 EC50(nM) = 230.0 |
| 2 | P31644_DMU | DMU | n/a | 5288728 | n/a | DECYL-BETA-D-MALTOPYRANOSIDE | n/a | |
| 3 | P31644_DZP | DZP | DB00829 | 3016 | CHEMBL12 | 7-CHLORO-1-METHYL-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE | ligand | Ki(nM) = 11.0 IC50(nM) = 17.0 Kd(nM) = 23.0 EC50(nM) = 45.0 |
| 4 | P31644_EIE | EIE | n/a | 5081 | CHEMBL6597 | ethyl 8-[(azanylidene-$l^{4}-azanylidene)amino]-5-methyl-6-oxidanylidene-4~{H}-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate | n/a | |
| 5 | P31644_FYP | FYP | DB01205 | 3373 | CHEMBL407 | ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate | antagonist | Ki(nM) = 0.6 |
| 6 | P31644_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 7 | P31644_NO3 | NO3 | DB14049 | 943 | CHEMBL186200 | NITRATE ION | n/a | |
| 8 | P31644_P9N | P9N | DB12308 | 31402 | CHEMBL210952 | Pregnanolone | n/a | |
| 9 | P31644_QI0 | QI0 | DB11877 | 57336276 | CHEMBL3681419 | Basmisanil | modulator | |
| 10 | P31644_QK9 | QK9 | n/a | 11624499 | CHEMBL1080588 | 5-[bis(fluoranyl)methyl]-15-bromanyl-2,4,8,9,11-pentazatetracyclo[11.4.0.0^{2,6}.0^{8,12}]heptadeca-1(13),3,5,9,11,14,16-heptaene | n/a | |
| 11 | P31644_QKF | QKF | n/a | 160195842 | n/a | [1,1-bis(oxidanylidene)-1,4-thiazinan-4-yl]-[6-[[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4-yl]methoxy]pyridin-3-yl]methanone | n/a | |
| 12 | P31644_QM7 | QM7 | n/a | 134604371 | n/a | 6-[[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4-yl]methoxy]-~{N}-[(2~{S})-1-oxidanylpentan-2-yl]pyridine-3-carboxamide | n/a | |
| 13 | P31644_QMJ | QMJ | n/a | 5311203 | CHEMBL52030 | ethyl (7~{S})-15-methoxy-12-oxidanylidene-2,4,11-triazatetracyclo[11.4.0.0^{2,6}.0^{7,11}]heptadeca-1(17),3,5,13,15-pentaene-5-carboxylate | n/a | |
| 14 | P31644_QMU | QMU | n/a | 107926 | CHEMBL366947 | Bretazenil | n/a | |
| 15 | P31644_QR3 | QR3 | n/a | 146272740 | n/a | 2-[[5-methyl-3-(6-methylpyridazin-3-yl)-1,2-oxazol-4-yl]methyl]-5-(5-oxa-2-azaspiro[3.5]nonan-2-yl)pyridazin-3-one | n/a | |
| 16 | P31644_R63 | R63 | n/a | 104999 | CHEMBL1256850 | methyl 4-ethyl-6,7-dimethoxy-9H-pyrido[3,4-b]indole-3-carboxylate | n/a | |
| 17 | P31644_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 18 | P31644_DB00241 | n/a | DB00241 | n/a | n/a | Butalbital | potentiator | |
| 19 | P31644_DB00306 | n/a | DB00306 | n/a | n/a | Talbutal | potentiator | |
| 20 | P31644_DB00312 | n/a | DB00312 | n/a | n/a | Pentobarbital | positive allosteric modulator | |
| 21 | P31644_DB00371 | n/a | DB00371 | n/a | n/a | Meprobamate | positive allosteric modulator | |
| 22 | P31644_DB00395 | n/a | DB00395 | n/a | n/a | Carisoprodol | modulator | |
| 23 | P31644_DB00402 | n/a | DB00402 | n/a | n/a | Eszopiclone | positive allosteric modulator | |
| 24 | P31644_DB00418 | n/a | DB00418 | n/a | n/a | Secobarbital | potentiator | |
| 25 | P31644_VOK | VOK | DB00463 | 4099 | CHEMBL450 | Metharbital | potentiator | |
| 26 | P31644_DB00599 | n/a | DB00599 | n/a | n/a | Thiopental | potentiator | |
| 27 | P31644_DB00794 | n/a | DB00794 | n/a | n/a | Primidone | positive allosteric modulator | |
| 28 | P31644_DB00849 | n/a | DB00849 | n/a | n/a | Methylphenobarbital | potentiator | |
| 29 | P31644_EOH | EOH | DB00898 | 702 | CHEMBL545 | Ethanol | n/a | |
| 30 | P31644_DB01198 | n/a | DB01198 | n/a | n/a | Zopiclone | potentiator | |
| 31 | P31644_DB01351 | n/a | DB01351 | n/a | n/a | Amobarbital | potentiator | |
| 32 | P31644_DB01352 | n/a | DB01352 | n/a | n/a | Aprobarbital | potentiator | |
| 33 | P31644_DB01353 | n/a | DB01353 | n/a | n/a | Butobarbital | potentiator | |
| 34 | P31644_DB01354 | n/a | DB01354 | n/a | n/a | Heptabarbital | potentiator | |
| 35 | P31644_DB01355 | n/a | DB01355 | n/a | n/a | Hexobarbital | potentiator | |
| 36 | P31644_DB01483 | n/a | DB01483 | n/a | n/a | Barbital | potentiator | |
| 37 | P31644_DB01496 | n/a | DB01496 | n/a | n/a | Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione | potentiator | |
| 38 | P31644_DB01567 | n/a | DB01567 | n/a | n/a | Fludiazepam | potentiator |