Gene name: shc
Protein name: Squalene--hopene cyclase (SHC)
List of molecules and drugs that interact with protein P33247
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P33247_C8E | C8E | DB04233 | 5414 | n/a | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE | n/a | |
| 2 | P33247_LDA | LDA | DB04147 | 15433 | CHEMBL1233973 | LAURYL DIMETHYLAMINE-N-OXIDE | n/a | |
| 3 | P33247_R01 | R01 | DB03234 | 445986 | CHEMBL65230 | (4'-{[ALLYL(METHYL)AMINO]METHYL}-1,1'-BIPHENYL-4-YL)(4-BROMOPHENYL)METHANONE | n/a | IC50(nM) = 29.0 |
| 4 | P33247_R02 | R02 | n/a | 445988 | CHEMBL293005 | {4-[((1S,2S)-2-{[ALLYL(CYCLOPROPYL)AMINO]METHYL}CYCLOPROPYL)METHOXY]PHENYL}(4-BROMOPHENYL)METHANONE | n/a | |
| 5 | P33247_R03 | R03 | DB03888 | 445989 | CHEMBL66424 | ALLYL-{6-[3-(4-BROMO-PHENYL)-1-METHYL-1H-INDAZOL-6-YL]OXY}HEXYL)-N-METHYLAMINE | n/a | IC50(nM) = 289.0 |
| 6 | P33247_R04 | R04 | DB02139 | 445990 | CHEMBL65730 | (2E)-N-ALLYL-4-{[3-(4-BROMOPHENYL)-5-FLUORO-1-METHYL-1H-INDAZOL-6-YL]OXY}-N-METHYL-2-BUTEN-1-AMINE | n/a | IC50(nM) = 281.0 |
| 7 | P33247_R17 | R17 | DB03771 | 447559 | CHEMBL65553 | ALLYL-{4-[3-(4-BROMO-PHENYL)-BENZOFURAN-6-YLOXY]-BUT-2-ENYL}-METHYL-AMINE | n/a | IC50(nM) = 23.0 |
| 8 | P33247_R19 | R19 | DB02339 | 447560 | CHEMBL445353 | ALLYL-{6-[3-(4-BROMO-PHENYL)-BENZOFURAN-6-YLOXY]-HEXYL-}-METHYL-AMIN | n/a | IC50(nM) = 80.0 |
| 9 | P33247_R23 | R23 | DB03748 | n/a | CHEMBL66412 | METHYL-[4-(4-PIPERIDINE-1-YLMETHYL-PHENYL)-CYCLOHEXYL]-CARBAMINIC ACID-(4-CHLOROPHENYL)-ESTER | n/a | IC50(nM) = 406.0 |
| 10 | P33247_R46 | R46 | n/a | 445991 | CHEMBL294809 | N-{6-[4-(6-BROMO-1,2-BENZISOTHIAZOL-3-YL)PHENOXY]HEXYL}-N-METHYL-2-PROPEN-1-AMINE | n/a | |
| 11 | P33247_R71 | R71 | DB02016 | 1949 | CHEMBL304858 | [4-({6-[ALLYL(METHYL)AMINO]HEXYL}OXY)-2-FLUOROPHENYL](4-BROMOPHENYL)METHANONE | n/a | IC50(nM) = 60.0 |
| 12 | P33247_R79 | R79 | DB02544 | 445992 | CHEMBL67133 | N-(6-{[3-(4-BROMOPHENYL)-1,2-BENZISOTHIAZOL-6-YL]OXY}HEXYL)-N-METHYLPROP-2-EN-1-AMINE | n/a | IC50(nM) = 306.0 |
| 13 | P33247_R88 | R88 | DB08458 | 445987 | CHEMBL62855 | (4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPROPYL(METHYL)AMINO]BUT-2-ENYL}OXY)PHENYL]METHANONE | n/a | IC50(nM) = 18.0 |
| 14 | P33247_W37 | W37 | n/a | 447553 | CHEMBL65024 | N-(6-{[1-(4-BROMOPHENYL)ISOQUINOLIN-6-YL]OXY}HEXYL)-N-METHYLPROP-2-EN-1-AMINE | n/a | |
| 15 | P33247_SQA | SQA | DB03874 | 448904 | n/a | 2-AZASQUALENE | n/a |