Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
P33334 PRP8_YEAST
Gene name: PRP8
Protein name: Pre-mRNA-splicing factor 8

List of molecules and drugs that interact with protein P33334

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 P33334_5G1 5G1 n/a 79883 CHEMBL3237995 2-chlorobenzohydrazide n/a
2 P33334_AC6 AC6 n/a 7469 CHEMBL201083 P-HYDROXYACETOPHENONE n/a
3 P33334_DEW DEW n/a 16770323 n/a 2-azanyl-1-(6,7-dihydro-4~{H}-thieno[3,2-c]pyridin-5-yl)ethanone n/a
4 P33334_DMS DMS DB01093 679 CHEMBL504 DIMETHYL SULFOXIDE n/a
5 P33334_EPE EPE DB16872 23830;23831;3275884; CHEMBL1232545 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID n/a
6 P33334_GTP GTP DB04137 6830;5280317;135398633; CHEMBL1233147 GUANOSINE-5'-TRIPHOSPHATE n/a
7 P33334_IHP IHP DB14981 n/a CHEMBL1233511 INOSITOL HEXAKISPHOSPHATE n/a
8 P33334_KGN KGN n/a n/a n/a D-chiro inositol hexakisphosphate n/a
9 P33334_L5W L5W n/a n/a n/a ~{N}-oxidanylbicyclo[2.2.1]heptane-1-carboxamide n/a
10 P33334_MG MG n/a 888 n/a MAGNESIUM ION n/a
11 P33334_PGO PGO DB04349 439846 n/a S-1,2-PROPANEDIOL n/a
12 P33334_PGR PGR DB02159 259994 n/a R-1,2-PROPANEDIOL n/a
13 P33334_R8Y R8Y n/a 61008719 n/a N-ethyl-N-(thiophene-2-carbonyl)-beta-alanine n/a
14 P33334_R9G R9G n/a 786913 n/a (3-methoxyphenyl)(pyrrolidin-1-yl)methanone n/a
15 P33334_R9S R9S n/a 17145724 n/a 2-(2-methylphenyl)acetamide n/a
16 P33334_RBJ RBJ n/a 13104924 n/a 4-[(methylamino)methyl]phenol n/a
17 P33334_SO4 SO4 DB14546 1117 n/a SULFATE ION n/a
18 P33334_TBJ TBJ n/a 38154784 n/a N-cyclopentyl-N'-{[(2R)-oxolan-2-yl]methyl}urea n/a
19 P33334_TJV TJV n/a 2776126 n/a 1,3-benzodioxole-5-carbothioamide n/a
20 P33334_USP USP n/a 146160376 n/a (2R)-6-amino-3-methyl-2,3-dihydro-1,3-benzoxazol-2-ol n/a
21 P33334_UVO UVO n/a 83801 n/a 5-methoxy-2-nitrosophenol n/a
22 P33334_UWI UWI n/a 13197203 n/a oxane-4-carboxamide n/a
23 P33334_UYY UYY n/a 75540 CHEMBL2436421 2-methoxybenzamide n/a
24 P33334_UZ8 UZ8 n/a 39902939 n/a [2-(methylsulfanyl)pyridin-3-yl](pyrrolidin-1-yl)methanone n/a
25 P33334_V2L V2L n/a 13478011 CHEMBL164646 1-(1-benzyl-1H-imidazol-2-yl)methanamine n/a
26 P33334_V2U V2U n/a 2303719 CHEMBL4753202 2-chloro-N-(3,5-dimethoxyphenyl)acetamide n/a
27 P33334_V40 V40 n/a 165416591 n/a (2S)-1-{[(1R,2R)-2-(aminomethyl)cyclohexyl]methyl}pyrrolidin-2-ol n/a
28 P33334_V5Y V5Y n/a 3772 n/a piperidine-4-carboxamide n/a
29 P33334_V6R V6R n/a 79025218 CHEMBL4917818 (2S)-2-amino-N-[(2-fluorophenyl)methyl]-N-methylbutanamide n/a
30 P33334_V6Z V6Z n/a 531380 n/a methyl N-(2-chlorobenzoyl)glycinate n/a
31 P33334_V73 V73 n/a 3276510 n/a N-(2-hydroxyethyl)-N-methyl-2-phenylacetamide n/a
32 P33334_V86 V86 n/a 3450992 n/a 2-bromo-N-ethylbenzamide n/a
33 P33334_V8E V8E n/a 28705026;28705027; n/a (4-butanoylpiperazin-1-yl)acetic acid n/a
34 P33334_V99 V99 n/a 7174100 n/a 3-ethyl-5-(ethylsulfanyl)-4H-1,2,4-triazol-4-amine n/a
35 P33334_V9P V9P n/a 2757504 n/a 1-(2-chloroethyl)-1H-imidazole n/a
36 P33334_V9X V9X n/a 351791 CHEMBL1338144 3-(1H-indol-3-yl)propanamide n/a
37 P33334_VB9 VB9 n/a 16768103 n/a 3-[2-(dimethylamino)ethyl]-2-sulfanylidene-2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-one n/a
38 P33334_VBI VBI n/a 30168764 n/a N~2~-(3-chlorophenyl)-N~2~-(methanesulfonyl)-N-methylglycinamide n/a
39 P33334_VBO VBO n/a 7536486 n/a methyl 3-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoate n/a
40 P33334_VCO VCO n/a 6380215 n/a ethyl (2Z)-(azepan-2-ylidene)(cyano)acetate n/a
41 P33334_VD6 VD6 n/a 677407;6920340; n/a (2R)-1-benzylpiperidine-2-carboxylic acid n/a
42 P33334_VDD VDD n/a 40560276 n/a (2S)-2-[(pyridin-2-yl)sulfanyl]propanoic acid n/a
43 P33334_VDI VDI n/a 602761 CHEMBL1343297 1-(4-chlorophenyl)cyclobutane-1-carboxylic acid n/a
44 P33334_VF3 VF3 n/a 3157272 n/a 4-(thiophene-2-sulfonyl)morpholine n/a
45 P33334_VF9 VF9 n/a 96202003 n/a 1-[(2S)-2-(furan-2-yl)azepan-1-yl]ethan-1-one n/a
46 P33334_VGU VGU n/a n/a n/a N-[(1E)-2-(hydroxyamino)-2-oxoethylidene]benzamide n/a
47 P33334_VIE VIE n/a 43809056 CHEMBL4548818 2-(aminomethyl)-N,N-dimethyl-2,3-dihydro-1H-inden-2-amine n/a
48 P33334_VIK VIK n/a 7116288 n/a methyl [(3S)-1,1-dioxo-1lambda~6~-thiolan-3-yl]acetate n/a
49 P33334_VJI VJI n/a 66516440 n/a (1R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethane-1,2-diamine n/a
50 P33334_VJO VJO n/a 2788662 n/a N-(2,3-dihydro-1,4-benzodioxin-6-yl)methanesulfonamide n/a
51 P33334_VJY VJY n/a 7131592 CHEMBL4586401 N-[(5-acetylthiophen-2-yl)methyl]acetamide n/a
52 P33334_VKX VKX n/a 28471934 n/a (5R,8aS)-8a-phenylhexahydropyrrolo[1,2-a]pyrimidin-6(2H)-one n/a
53 P33334_VLI VLI n/a 1718499 n/a (3S)-3-hydroxy-6-methyl-3-(trifluoromethyl)-1,3-dihydro-2H-indol-2-one n/a
54 P33334_VNC VNC n/a 4584366 n/a methyl N-(benzenesulfonyl)-N-methylglycinate n/a
55 P33334_VNN VNN n/a 17250257 n/a (4-methylpiperazin-1-yl)(5-methylthiophen-3-yl)methanone n/a
56 P33334_VNU VNU n/a 83623658 n/a N-(1-phenylcyclobutyl)glycinamide n/a
57 P33334_VO5 VO5 n/a 43212844 n/a N-ethyl-2-methoxybenzene-1-sulfonamide n/a
58 P33334_VO9 VO9 n/a 43576865 n/a N-cyclopropyl-N-(2-hydroxyethyl)thiophene-2-carboxamide n/a
59 P33334_VP0 VP0 n/a 693111 n/a [(1S)-2-acetyl-1,2,3,4-tetrahydroisoquinolin-1-yl]acetic acid n/a
60 P33334_VP3 VP3 n/a 101359 CHEMBL3544869 4-(4-fluorophenyl)-4-oxobutanoic acid n/a
61 P33334_VPE VPE n/a 946246 n/a (3S)-3-methyl-5-oxo-5-[(1,3-thiazol-2-yl)amino]pentanoic acid n/a
62 P33334_VPK VPK n/a 235275 n/a ethyl pyridin-3-ylcarbamate n/a
63 P33334_VQ2 VQ2 n/a 2773375 n/a [4-(diethylcarbamoyl)phenyl]boronic acid n/a
64 P33334_VQ6 VQ6 n/a 93280638 n/a (2R)-(cyclopropylamino)(2,6-difluorophenyl)acetic acid n/a
65 P33334_VR6 VR6 n/a 45259124 n/a N-[(furan-2-yl)methyl]-2-[(pyridin-2-yl)oxy]ethan-1-amine n/a
66 P33334_VRR VRR n/a 90196 n/a ethyl N-benzyl-beta-alaninate n/a
67 P33334_VTC VTC n/a 29877 n/a 3-aminophenyl dimethylcarbamate n/a
68 P33334_VTL VTL n/a 16928 CHEMBL3747068 4-(2-hydroxyethyl)-2-methoxyphenol n/a
69 P33334_VTT VTT n/a 2760084 n/a 3-methylthiophene-2-carbohydrazide n/a
70 P33334_VTW VTW n/a 737474 CHEMBL4089780 3-phenyl-1,2-oxazole-5-carboxylic acid n/a
71 P33334_VU9 VU9 n/a 7096 CHEMBL9434 1-phenylpiperazine n/a
72 P33334_VUU VUU n/a 51130752 n/a N-cyclopropyl-N'-[2-(thiophen-2-yl)ethyl]guanidine n/a
73 P33334_VV0 VV0 n/a 16773446 n/a 4-amino-3-methyl-N-(propan-2-yl)benzamide n/a
74 P33334_VV5 VV5 n/a 25669160 CHEMBL4929846 N-[2-(thiophen-2-yl)ethyl]pyridine-3-carboxamide n/a
75 P33334_VVK VVK n/a 2759622 n/a N-(2-methoxyphenyl)-2-methyl-L-alanine n/a
76 P33334_VVR VVR n/a 81596 n/a 3-phenoxypropanoic acid n/a
77 P33334_VW3 VW3 n/a 21935074 CHEMBL569423 N-hydroxy-3-phenoxypropanamide n/a
78 P33334_VWC VWC n/a 2063431 n/a 4-(2-methylpropoxy)benzohydrazide n/a
79 P33334_VXF VXF n/a 7537568 n/a 1-[2-(morpholin-4-yl)pyridin-4-yl]methanamine n/a
80 P33334_VY6 VY6 n/a 806406;6945614; n/a 2-[(morpholin-4-yl)methyl]furan-3-carboxylic acid n/a
81 P33334_VYO VYO n/a 7784001 n/a methyl [(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]acetate n/a
82 P33334_VZC VZC n/a 12296732 n/a 2-cyano-N-methyl-N-phenylacetamide n/a
83 P33334_VZQ VZQ n/a 7021590 n/a 4-[(acetyloxy)methyl]benzoic acid n/a
84 P33334_W0C W0C n/a 45799408 n/a N-(pentan-3-yl)-N'-(pyridin-3-yl)urea n/a
85 P33334_W1E W1E n/a 52542578 n/a 2-methylpropyl [(3R)-1,1-dioxo-2,3-dihydro-1H-1lambda~6~-thiophen-3-yl]acetate n/a
86 P33334_W1N W1N n/a 2761574;7009868; n/a (3S)-3-amino-4-(2-fluorophenyl)butanoic acid n/a
87 P33334_W1W W1W n/a 2801428 n/a 6-[(pyridin-2-yl)sulfanyl]pyridin-3-amine n/a
88 P33334_W2I W2I n/a 20121155 n/a 1-[(3-aminophenyl)methyl]piperidin-4-ol n/a
89 P33334_W2O W2O n/a 7000171 n/a D-phenylalaninamide n/a
90 P33334_W2U W2U n/a 718256 n/a (2S)-2-phenoxypropanehydrazide n/a
91 P33334_W3H W3H n/a 6925762 n/a (3R)-3-(4-chlorobenzene-1-sulfonyl)butanoic acid n/a
92 P33334_W4L W4L n/a 54986985 n/a N~2~-[(6-chloropyridin-3-yl)methyl]-N,N~2~-diethylglycinamide n/a
93 P33334_W4R W4R n/a 43407394 n/a methyl N-[(2,6-dichlorophenyl)acetyl]-N-methylglycinate n/a
94 P33334_W50 W50 n/a 1122386 n/a (2S)-1-(2-bromophenoxy)-3-(pyrrolidin-1-yl)propan-2-ol n/a
95 P33334_W5C W5C n/a 780424 n/a 2-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]-1-phenylethan-1-one n/a
96 P33334_W5H W5H n/a 89095 n/a (1-methyl-1H-pyrrol-2-yl)acetic acid n/a
97 P33334_W6H W6H n/a 75413211 n/a methyl N-methyl-N-[(2E)-3-(thiophen-3-yl)prop-2-enoyl]glycinate n/a
98 P33334_W6R W6R n/a 4117885 n/a N-[(thiophen-2-yl)methyl]butanamide n/a
99 P33334_W6W W6W n/a 17477682 n/a N~3~-[(2-bromophenyl)methyl]-N~3~-methyl-beta-alaninamide n/a
100 P33334_W7T W7T n/a 43210022 n/a N-(2-aminoethyl)-2-cyclohexylacetamide n/a
101 P33334_W8K W8K n/a 12175281 n/a N-[(3-bromophenyl)methyl]acetamide n/a
102 P33334_W98 W98 n/a 60745829 n/a N-cyclopropyl-N-[(thiophen-2-yl)methyl]methanesulfonamide n/a
103 P33334_W9O W9O n/a 165416224 n/a N-methyl-1-{(1S,2R)-2-[(1,2,4-triazolidin-1-yl)methyl]cyclohexyl}methanamine n/a
104 P33334_WA8 WA8 n/a 53515617 n/a 2-(2-oxopyridin-1(2H)-yl)-N,N-di(prop-2-en-1-yl)acetamide n/a
105 P33334_WAX WAX n/a 6485064 n/a (3-aminophenyl)(morpholin-4-yl)methanone n/a
106 P33334_WB6 WB6 n/a 51683231 n/a 5-chloro-N,1-dimethyl-N-[(2S)-pentan-2-yl]-1H-imidazole-4-sulfonamide n/a
107 P33334_WBB WBB n/a 45860780 n/a N-methoxy-2-(2-methylphenyl)acetamide n/a
108 P33334_WBF WBF n/a 4388854 n/a 2-[(2-fluorophenyl)sulfanyl]acetohydrazide n/a
109 P33334_WBL WBL n/a 93658484 n/a propyl (2S)-2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]propanoate n/a
110 P33334_WCB WCB n/a 40137163 n/a 1-[(2S)-2-methylmorpholin-4-yl]-2-(thiophen-3-yl)ethan-1-one n/a
111 P33334_WD4 WD4 n/a 53936882 n/a 1-cyclopropylimidazolidin-2-one n/a
112 P33334_WD8 WD8 n/a 55028598 n/a methyl N-(propan-2-yl)-N-(thiophene-3-carbonyl)glycinate n/a
113 P33334_WDC WDC n/a 60960377 n/a 2-{[(5-amino-2-chlorophenyl)methyl](methyl)amino}ethan-1-ol n/a
114 P33334_WDH WDH n/a 71974232 n/a N,N~2~-diethyl-N~2~-(2-methylpyrimidin-4-yl)glycinamide n/a
115 P33334_WE5 WE5 n/a 683862 n/a methyl (3R)-5-oxo-1-phenylpyrrolidine-3-carboxylate n/a
116 P33334_SY4 SY4 n/a 43550982 CHEMBL4920863 ~{N}-[5-azanyl-2,4-bis(fluoranyl)phenyl]propane-1-sulfonamide n/a
117 P33334_SY7 SY7 n/a 146160373 n/a 2-methoxy-4-[[(4~{S},5~{S})-2,4,5-tris(2-methoxypyridin-4-yl)imidazolidin-1-yl]methyl]pyridine n/a
118 P33334_SYJ SYJ n/a 697876 n/a 2-fluoranyl-~{N}-(furan-2-ylmethyl)benzenesulfonamide n/a
119 P33334_SYV SYV n/a 6486006 n/a 6-azanyl-3-methyl-1,3-benzoxazol-2-one n/a
120 P33334_SZA SZA n/a 45757129 n/a ~{N}-(2-thiophen-2-ylethyl)pyridine-4-carboxamide n/a
121 P33334_T9S T9S n/a 18953633 n/a ethyl 1,3-dihydro-2H-pyrrolo[3,4-c]pyridine-2-carboxylate n/a
122 P33334_T9V T9V n/a 5827 CHEMBL3183230 N-(4-methoxyphenyl)acetamide n/a