Gene name: SPR
Protein name: Sepiapterin reductase (SPR)
List of molecules and drugs that interact with protein P35270
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P35270_43O | 43O | n/a | 52911386 | CHEMBL3948731 | N-[2-(5-hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide | n/a | |
| 2 | P35270_4KL | 4KL | n/a | 5699;5280517; | CHEMBL312535 | Xanthuric acid | n/a | |
| 3 | P35270_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 4 | P35270_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 5 | P35270_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 6 | P35270_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 7 | P35270_H4E | H4E | n/a | 242793 | n/a | ethyl 4-azanyl-3-bromanyl-benzoate | n/a | |
| 8 | P35270_H4H | H4H | n/a | 95615078 | n/a | (1~{R},2~{S},4~{S})-~{N}-(3-chloranyl-4-cyano-phenyl)sulfonylbicyclo[2.2.1]heptane-2-carboxamide | n/a | |
| 9 | P35270_H4T | H4T | n/a | 75426260 | CHEMBL4442449 | 6-azaspiro[3.4]octan-6-yl-[2,4-bis(chloranyl)-6-oxidanyl-phenyl]methanone | n/a | |
| 10 | P35270_H5B | H5B | n/a | 289393 | n/a | 4-bromanyl-1-oxidanyl-naphthalene-2-carboxylic acid | n/a | |
| 11 | P35270_H5E | H5E | n/a | 75517293 | n/a | 6-[(4-~{tert}-butyl-1,3-thiazol-2-yl)methyl]-4,6-diazaspiro[2.4]heptane-5,7-dione | n/a | |
| 12 | P35270_H6E | H6E | n/a | 97841189 | n/a | 2-[[(3~{R})-oxan-3-yl]methylsulfonyl]-2-azaspiro[4.5]decane | n/a | |
| 13 | P35270_NAP | NAP | DB03461 | 5885;57525501; | CHEMBL295069 | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | n/a | |
| 14 | P35270_NDP | NDP | DB02338 | 5884;134821689; | CHEMBL407009 | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | n/a | |
| 15 | P35270_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 16 | P35270_QGV | QGV | n/a | 16259746 | CHEMBL4643853 | (2-hydroxyphenyl)[3-methyl-1-(pyridin-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl]methanone | n/a | |
| 17 | P35270_SAS | SAS | DB00795 | n/a | CHEMBL421 | 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID | n/a | |
| 18 | P35270_SFY | SFY | DB00891 | 5336 | CHEMBL700 | 4-amino-N-(pyridin-2-yl)benzenesulfonamide | n/a | |
| 19 | P35270_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 20 | P35270_YTZ | YTZ | DB06147 | 5340 | CHEMBL437 | 4-amino-N-(1,3-thiazol-2-yl)benzenesulfonamide | n/a | |
| 21 | P35270_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 22 | P35270_OAA | OAA | DB02637 | 3260017;140658388; | n/a | Oxaloacetate Ion | n/a | |
| 23 | P35270_BIO | BIO | DB03886 | 444475;5287790;135449517; | n/a | Biopterin | n/a | |
| 24 | P35270_ASE | ASE | DB04275 | 903 | CHEMBL33103 | N-acetylserotonin | n/a | IC50(nM) = 5000.0 |