P35354 PGH2_HUMAN
Gene name: PTGS2
Protein name: Prostaglandin G/H synthase

List of molecules and drugs that interact with protein P35354

#	DrugDomain Data	PBD ligand	DrugBank Accession	PubChem	ChEMBL	Name	Drug action	Affinity data
1	P35354_AKR	AKR	DB02579	6581;19966351;	CHEMBL1213529	ACRYLIC ACID	n/a
2	P35354_BOG	BOG	n/a	62852	CHEMBL446037	octyl beta-D-glucopyranoside	n/a
3	P35354_COH	COH	DB02110	n/a	n/a	PROTOPORPHYRIN IX CONTAINING CO	n/a
4	P35354_EDO	EDO	n/a	174	CHEMBL457299	1,2-ETHANEDIOL	n/a
5	P35354_FLF	FLF	DB02266	3371	CHEMBL23588	2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID	inhibitor	IC50(nM) = 16.0
6	P35354_GOL	GOL	DB09462	753	CHEMBL692	GLYCEROL	n/a
7	P35354_ID8	ID8	DB00784	4044	CHEMBL686	2-[(2,3-DIMETHYLPHENYL)AMINO]BENZOIC ACID	inhibitor	Ki(nM) = 160.0 IC50(nM) = 2900.0
8	P35354_JMS	JMS	DB00939	4037	CHEMBL509	2-[(2,6-dichloro-3-methyl-phenyl)amino]benzoic acid	inhibitor	Ki(nM) = 200.0 IC50(nM) = 40.0
9	P35354_NAG	NAG	DB00141	24139	CHEMBL447878	2-acetamido-2-deoxy-beta-D-glucopyranose	n/a
10	P35354_NH4	NH4	n/a	223;16741146;	n/a	AMMONIUM ION	n/a
11	P35354_PO4	PO4	DB14523	1061	n/a	PHOSPHATE ION	n/a
12	P35354_RCX	RCX	DB00533	5090	CHEMBL122	Rofecoxib	inhibitor	Ki(nM) = 310.0 IC50(nM) = 1.0
13	P35354_SAL	SAL	DB00936	338;118212070;	CHEMBL424	2-HYDROXYBENZOIC ACID	inhibitor	Ki(nM) = 10000.0 IC50(nM) = 40000.0
14	P35354_TLF	TLF	DB09216	610479	CHEMBL121626	2-[(3-chloro-2-methylphenyl)amino]benzoic acid	antagonist	IC50(nM) = 880.0
15	P35354_LAX	LAX	DB00154	5280581	CHEMBL465183	Dihomo-gamma-linolenic acid	n/a
16	P35354_EPA	EPA	DB00159	446284	CHEMBL460026	Icosapent	inhibitor
17	P35354_BHA	BHA	DB00233	4649	CHEMBL1169	Aminosalicylic acid	inhibitor
18	P35354_DB00244	n/a	DB00244	n/a	n/a	Mesalazine	inhibitor	Ki(nM) = 10000.0 IC50(nM) = 7530.0
19	P35354_TYL	TYL	DB00316	1983	CHEMBL112	Acetaminophen	inhibitor	Ki(nM) = 10000.0 IC50(nM) = 141000.0
20	P35354_IMN	IMN	DB00328	3715	CHEMBL6	Indomethacin	inhibitor	Ki(nM) = 130.0 IC50(nM) = 0.14 Kd(nM) = 92.0
21	P35354_NBO	NBO	DB00461	4409	CHEMBL1070	Nabumetone	inhibitor	Ki(nM) = 10000.0
22	P35354_DB00465	n/a	DB00465	n/a	n/a	Ketorolac	inhibitor	Ki(nM) = 75.0 IC50(nM) = 120.0
23	P35354_DB00469	n/a	DB00469	n/a	n/a	Tenoxicam	inhibitor
24	P35354_DB00480	n/a	DB00480	n/a	n/a	Lenalidomide	negative modulator
25	P35354_CEL	CEL	DB00482	2662	CHEMBL118	Celecoxib	inhibitor	Ki(nM) = 0.47 IC50(nM) = 0.52 Kd(nM) = 789.09
26	P35354_TLT	TLT	DB00500	5509	CHEMBL1020	Tolmetin	inhibitor	Ki(nM) = 820.0 IC50(nM) = 820.0
27	P35354_DB00554	n/a	DB00554	n/a	n/a	Piroxicam	inhibitor	Ki(nM) = 170.0 IC50(nM) = 102000.0
28	P35354_DB00573	n/a	DB00573	n/a	n/a	Fenoprofen	inhibitor	Ki(nM) = 5900.0
29	P35354_COX	COX	DB00580	119607	CHEMBL865	Valdecoxib	inhibitor	Ki(nM) = 870.0 IC50(nM) = 5.0
30	P35354_DIF	DIF	DB00586	3033	CHEMBL139	Diclofenac	inhibitor	IC50(nM) = 5.0
31	P35354_DB00605	n/a	DB00605	n/a	n/a	Sulindac	inhibitor
32	P35354_DB00712	n/a	DB00712	n/a	n/a	Flurbiprofen	inhibitor	Ki(nM) = 770.0 IC50(nM) = 10.0
33	P35354_DB00749	n/a	DB00749	n/a	n/a	Etodolac	inhibitor	Ki(nM) = 940.0 IC50(nM) = 9.4
34	P35354_NPS	NPS	DB00788	156391	CHEMBL154	Naproxen	inhibitor	IC50(nM) = 900.0
35	P35354_SAS	SAS	DB00795	n/a	CHEMBL421	Sulfasalazine	inhibitor
36	P35354_P1Z	P1Z	DB00812	4781	CHEMBL101	Phenylbutazone	inhibitor
37	P35354_MXM	MXM	DB00814	54677470	CHEMBL599	Meloxicam	inhibitor	Ki(nM) = 230.0 IC50(nM) = 0.49
38	P35354_DB00821	n/a	DB00821	n/a	n/a	Carprofen	inhibitor	Ki(nM) = 4300.0 IC50(nM) = 5.3
39	P35354_1FL	1FL	DB00861	3059	CHEMBL898	Diflunisal	inhibitor	Ki(nM) = 8200.0
40	P35354_DB00870	n/a	DB00870	n/a	n/a	Suprofen	inhibitor	Ki(nM) = 8300.0 IC50(nM) = 2750.0
41	P35354_AIN	AIN	DB00945	2244	CHEMBL25	Acetylsalicylic acid	inhibitor	Ki(nM) = 7500.0 IC50(nM) = 2400.0
42	P35354_27R	27R	DB00963	60726	CHEMBL1077	Bromfenac	inhibitor
43	P35354_BJ6	BJ6	DB00991	4614;52326892;	CHEMBL1071	Oxaprozin	inhibitor	Ki(nM) = 10000.0 IC50(nM) = 110.0
44	P35354_DB01009	n/a	DB01009	n/a	n/a	Ketoprofen	inhibitor	Ki(nM) = 240.0 IC50(nM) = 26.0
45	P35354_DB01014	n/a	DB01014	n/a	n/a	Balsalazide	inhibitor
46	P35354_DB01050	n/a	DB01050	n/a	n/a	Ibuprofen	inhibitor	Ki(nM) = 7200.0 IC50(nM) = 100.0
47	P35354_LUR	LUR	DB01283	151166	CHEMBL404108	Lumiracoxib	inhibitor	Ki(nM) = 320.0 IC50(nM) = 7.0
48	P35354_DB01397	n/a	DB01397	n/a	n/a	Magnesium salicylate	inhibitor
49	P35354_DB01399	n/a	DB01399	n/a	n/a	Salsalate	inhibitor	Ki(nM) = 10000.0
50	P35354_DB01401	n/a	DB01401	n/a	n/a	Choline magnesium trisalicylate	inhibitor	Ki(nM) = 10000.0
51	P35354_DB01419	n/a	DB01419	n/a	n/a	Antrafenine	inhibitor
52	P35354_DB01435	n/a	DB01435	n/a	n/a	Antipyrine	inhibitor
53	P35354_DB01600	n/a	DB01600	n/a	n/a	Tiaprofenic acid	inhibitor
54	P35354_5CH	5CH	DB01628	123619	CHEMBL416146	Etoricoxib	inhibitor	Ki(nM) = 69.0 IC50(nM) = 70.0
55	P35354_STL	STL	DB02709	445154	CHEMBL165	Resveratrol	inhibitor	Ki(nM) = 10000.0 IC50(nM) = 750.0
56	P35354_S58	S58	DB03477	1396	CHEMBL1235806	1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole	inhibitor	IC50(nM) = 9.3
57	P35354_PGX	PGX	DB03866	5280883	n/a	Prostaglandin G2	inhibitor
58	P35354_NFL	NFL	DB04552	4488	CHEMBL63323	Niflumic acid	inhibitor	Ki(nM) = 5400.0
59	P35354_LCF	LCF	DB04725	133021	CHEMBL300982	Licofelone	n/a	IC50(nM) = 370.0
60	P35354_NIM	NIM	DB04743	4495	CHEMBL56367	Nimesulide	inhibitor	Ki(nM) = 180.0 IC50(nM) = 15.0
61	P35354_DB05095	n/a	DB05095	n/a	n/a	Cimicoxib	modulator	IC50(nM) = 5.0
62	P35354_DB06725	n/a	DB06725	n/a	n/a	Lornoxicam	inhibitor
63	P35354_DB06736	n/a	DB06736	n/a	n/a	Aceclofenac	inhibitor
64	P35354_DB06802	n/a	DB06802	n/a	n/a	Nepafenac	inhibitor
65	P35354_PXB	PXB	DB08439	119828;6335917;	CHEMBL1206690	Parecoxib	inhibitor
66	P35354_DB08910	n/a	DB08910	n/a	n/a	Pomalidomide	inhibitor
67	P35354_P0T	P0T	DB09061	644019	CHEMBL190461	Cannabidiol	inhibitor
68	P35354_DB09212	n/a	DB09212	n/a	n/a	Loxoprofen	antagonist	IC50(nM) = 13500.0
69	P35354_IBP	IBP	DB09213	39912	CHEMBL175	Dexibuprofen	inhibitor	IC50(nM) = 730.0
70	P35354_9KL	9KL	DB09214	667550	CHEMBL75435	Dexketoprofen	antagonist	IC50(nM) = 27.0
71	P35354_DB09215	n/a	DB09215	n/a	n/a	Droxicam	inhibitor
72	P35354_DB09217	n/a	DB09217	n/a	n/a	Firocoxib	inhibitor	IC50(nM) = 140.0
73	P35354_DB09285	n/a	DB09285	n/a	n/a	Morniflumate	modulator
74	P35354_DB09288	n/a	DB09288	n/a	n/a	Propacetamol	antagonist
75	P35354_DB09295	n/a	DB09295	n/a	n/a	Talniflumate	antagonist
76	P35354_DB11071	n/a	DB11071	n/a	n/a	Phenyl salicylate	inhibitor
77	P35354_DB11079	n/a	DB11079	n/a	n/a	Trolamine salicylate	inhibitor
78	P35354_DB11201	n/a	DB11201	n/a	n/a	Menthyl salicylate	antagonist
79	P35354_DB11323	n/a	DB11323	n/a	n/a	Glycol salicylate	antagonist
80	P35354_DB11327	n/a	DB11327	n/a	n/a	Dipyrithione	n/a
81	P35354_DB11752	n/a	DB11752	n/a	n/a	Bryostatin 1	inducer
82	P35354_DB13167	n/a	DB13167	n/a	n/a	Alclofenac	antagonist
83	P35354_A4Z	A4Z	DB13346	2466	CHEMBL94394	Bufexamac	inhibitor
84	P35354_DB13501	n/a	DB13501	n/a	n/a	Bendazac	n/a
85	P35354_DB13783	n/a	DB13783	n/a	n/a	Acemetacin	antagonist
86	P35354_DB14011	n/a	DB14011	n/a	n/a	Nabiximols	inhibitor