Gene name: ADRA1B
Protein name: Alpha-1B adrenergic receptor
List of molecules and drugs that interact with protein P35368
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P35368_DB00211 | n/a | DB00211 | n/a | n/a | Midodrine | agonist | |
| 2 | P35368_DB00246 | n/a | DB00246 | n/a | n/a | Ziprasidone | antagonist | |
| 3 | P35368_DB00248 | n/a | DB00248 | n/a | n/a | Cabergoline | binder | |
| 4 | P35368_DB00298 | n/a | DB00298 | n/a | n/a | Dapiprazole | antagonist | |
| 5 | P35368_TP0 | TP0 | DB00321 | 2160 | CHEMBL629 | Amitriptyline | antagonist | |
| 6 | P35368_DB00334 | n/a | DB00334 | n/a | n/a | Olanzapine | antagonist | |
| 7 | P35368_DB00346 | n/a | DB00346 | n/a | n/a | Alfuzosin | antagonist | Ki(nM) = 2.8 |
| 8 | P35368_DB00363 | n/a | DB00363 | n/a | n/a | Clozapine | antagonist | |
| 9 | P35368_LNR | LNR | DB00368 | 439260 | CHEMBL1437 | Norepinephrine | agonist | Ki(nM) = 20400.0 |
| 10 | P35368_DB00388 | n/a | DB00388 | n/a | n/a | Phenylephrine | agonist | EC50(nM) = 0.86 |
| 11 | P35368_DB00408 | n/a | DB00408 | n/a | n/a | Loxapine | binder | |
| 12 | P35368_XRA | XRA | DB00457 | 4893 | CHEMBL2 | Prazosin | antagonist | Ki(nM) = 0.06 |
| 13 | P35368_IXX | IXX | DB00458 | 3696 | CHEMBL11 | Imipramine | antagonist | |
| 14 | P35368_Z80 | Z80 | DB00477 | 2726 | CHEMBL71 | Chlorpromazine | inhibitor | |
| 15 | P35368_21B | 21B | DB00540 | 4543 | CHEMBL445 | Nortriptyline | antagonist | |
| 16 | P35368_CLU | CLU | DB00575 | 2803 | CHEMBL134 | Clonidine | agonist | |
| 17 | P35368_DB00590 | n/a | DB00590 | n/a | n/a | Doxazosin | n/a | Ki(nM) = 0.630957 |
| 18 | P35368_DB00622 | n/a | DB00622 | n/a | n/a | Nicardipine | antagonist | |
| 19 | P35368_DB00661 | n/a | DB00661 | n/a | n/a | Verapamil | antagonist | |
| 20 | P35368_ALE | ALE | DB00668 | 5816;139148732; | CHEMBL679 | Epinephrine | agonist | EC50(nM) = 75.0 |
| 21 | P35368_DB00679 | n/a | DB00679 | n/a | n/a | Thioridazine | antagonist | |
| 22 | P35368_DB00692 | n/a | DB00692 | n/a | n/a | Phentolamine | antagonist | Ki(nM) = 4.8 IC50(nM) = 11.0 |
| 23 | P35368_ERM | ERM | DB00696 | 8223 | CHEMBL442 | Ergotamine | partial agonist | |
| 24 | P35368_DB00706 | n/a | DB00706 | n/a | n/a | Tamsulosin | antagonist | Ki(nM) = 0.6 IC50(nM) = 4.2 EC50(nM) = 0.13 |
| 25 | P35368_DB00723 | n/a | DB00723 | n/a | n/a | Methoxamine | agonist | |
| 26 | P35368_DB00726 | n/a | DB00726 | n/a | n/a | Trimipramine | antagonist | |
| 27 | P35368_DB00734 | n/a | DB00734 | n/a | n/a | Risperidone | antagonist | |
| 28 | P35368_DB00745 | n/a | DB00745 | n/a | n/a | Modafinil | partial agonist | |
| 29 | P35368_DB00800 | n/a | DB00800 | n/a | n/a | Fenoldopam | inhibitor | |
| 30 | P35368_QDN | QDN | DB00908 | 441074 | CHEMBL1294 | Quinidine | antagonist | |
| 31 | P35368_DB00925 | n/a | DB00925 | n/a | n/a | Phenoxybenzamine | antagonist | |
| 32 | P35368_J5C | J5C | DB00935 | 4636 | CHEMBL762 | Oxymetazoline | agonist | Ki(nM) = 832.0 EC50(nM) = 5012.0 |
| 33 | P35368_DB01136 | n/a | DB01136 | n/a | n/a | Carvedilol | antagonist | |
| 34 | P35368_DB01142 | no_lig_id | DB01142 | n/a | n/a | Doxepin | antagonist | |
| 35 | P35368_DB01149 | n/a | DB01149 | n/a | n/a | Nefazodone | other/unknown | |
| 36 | P35368_DB01162 | n/a | DB01162 | n/a | n/a | Terazosin | antagonist | Ki(nM) = 1.15 EC50(nM) = 0.5 |
| 37 | P35368_DB01186 | n/a | DB01186 | n/a | n/a | Pergolide | agonist | Ki(nM) = 691.83 |
| 38 | P35368_08Y | 08Y | DB01200 | 31101 | CHEMBL493 | Bromocriptine | antagonist | Ki(nM) = 1.38 |
| 39 | P35368_9SC | 9SC | DB01238 | 60795 | CHEMBL1112 | Aripiprazole | antagonist | Ki(nM) = 34.8 |
| 40 | P35368_DB01267 | n/a | DB01267 | n/a | n/a | Paliperidone | antagonist | |
| 41 | P35368_DB01403 | n/a | DB01403 | n/a | n/a | Methotrimeprazine | antagonist | |
| 42 | P35368_1WE | 1WE | DB01576 | 5826 | CHEMBL612 | Dextroamphetamine | inhibitor | |
| 43 | P35368_DB01579 | n/a | DB01579 | n/a | n/a | Phendimetrazine | agonist | |
| 44 | P35368_DB01608 | n/a | DB01608 | n/a | n/a | Periciazine | antagonist | |
| 45 | P35368_PMZ | PMZ | DB01614 | 6077 | CHEMBL39560 | Acepromazine | antagonist | |
| 46 | P35368_DB01622 | n/a | DB01622 | n/a | n/a | Thioproperazine | antagonist | |
| 47 | P35368_DB04855 | n/a | DB04855 | n/a | n/a | Dronedarone | antagonist | |
| 48 | P35368_NP1 | NP1 | DB05492 | 5276854 | CHEMBL609728 | Epicept NP-1 | n/a | |
| 49 | P35368_DB06144 | n/a | DB06144 | n/a | n/a | Sertindole | n/a | |
| 50 | P35368_DB06153 | n/a | DB06153 | n/a | n/a | Pizotifen | antagonist | |
| 51 | P35368_DB06207 | n/a | DB06207 | n/a | n/a | Silodosin | antagonist | IC50(nM) = 116.0 |
| 52 | P35368_DB06229 | n/a | DB06229 | n/a | n/a | Ocaperidone | n/a | |
| 53 | P35368_DB06262 | n/a | DB06262 | n/a | n/a | Droxidopa | agonist | |
| 54 | P35368_DB06694 | n/a | DB06694 | n/a | n/a | Xylometazoline | agonist | |
| 55 | P35368_DB09128 | n/a | DB09128 | n/a | n/a | Brexpiprazole | antagonist | |
| 56 | P35368_DB09185 | n/a | DB09185 | n/a | n/a | Viloxazine | antagonist | |
| 57 | P35368_DB09202 | n/a | DB09202 | n/a | n/a | Cirazoline | partial agonist | EC50(nM) = 63.0 |
| 58 | P35368_DB14185 | n/a | DB14185 | n/a | n/a | Aripiprazole lauroxil | antagonist |