P35462 DRD3_HUMAN
Gene name: DRD3
Protein name: D(3) dopamine receptor

List of molecules and drugs that interact with protein P35462

#	DrugDomain Data	PBD ligand	DrugBank Accession	PubChem	ChEMBL	Name	Drug action	Affinity data
1	P35462_ETQ	ETQ	DB15492	57267	CHEMBL8946	3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide	n/a
2	P35462_DB00246	n/a	DB00246	n/a	n/a	Ziprasidone	antagonist	Ki(nM) = 1.1
3	P35462_DB00248	n/a	DB00248	n/a	n/a	Cabergoline	agonist
4	P35462_DB00268	n/a	DB00268	n/a	n/a	Ropinirole	agonist	Ki(nM) = 19.0 EC50(nM) = 4.0
5	P35462_2GM	2GM	DB00320	10531	CHEMBL1732	Dihydroergotamine	agonist
6	P35462_DB00334	n/a	DB00334	n/a	n/a	Olanzapine	antagonist	Ki(nM) = 20.0
7	P35462_DB00363	n/a	DB00363	n/a	n/a	Clozapine	antagonist	Ki(nM) = 6.62 IC50(nM) = 450.0
8	P35462_DB00391	n/a	DB00391	n/a	n/a	Sulpiride	antagonist	Ki(nM) = 7.9 IC50(nM) = 66.22
9	P35462_DB00408	n/a	DB00408	n/a	n/a	Loxapine	binder	Ki(nM) = 18.0 IC50(nM) = 22.0
10	P35462_DB00409	n/a	DB00409	n/a	n/a	Remoxipride	antagonist	Ki(nM) = 70.0
11	P35462_G6L	G6L	DB00413	119570	CHEMBL301265	Pramipexole	agonist	Ki(nM) = 0.5 Kd(nM) = 0.0258 EC50(nM) = 0.812831
12	P35462_Z80	Z80	DB00477	2726	CHEMBL71	Chlorpromazine	inhibitor	Ki(nM) = 0.84
13	P35462_DB00490	n/a	DB00490	n/a	n/a	Buspirone	antagonist	Ki(nM) = 660.0
14	P35462_GMJ	GMJ	DB00502	3559	CHEMBL54	Haloperidol	inverse agonist	Ki(nM) = 0.2 IC50(nM) = 0.06
15	P35462_DB00543	n/a	DB00543	n/a	n/a	Amoxapine	antagonist	Ki(nM) = 11.0
16	P35462_H8G	H8G	DB00589	28864	CHEMBL157138	Lisuride	agonist	Ki(nM) = 1.7
17	P35462_OR9	OR9	DB00714	6005	CHEMBL53	Apomorphine	agonist	Ki(nM) = 2.6 IC50(nM) = 25.0 EC50(nM) = 7.0
18	P35462_DB00875	n/a	DB00875	n/a	n/a	Flupentixol	antagonist
19	P35462_LDP	LDP	DB00988	681	CHEMBL59	Dopamine	agonist	Ki(nM) = 3.0 IC50(nM) = 15.0 EC50(nM) = 0.11
20	P35462_1II	1II	DB01100	16362	CHEMBL1423	Pimozide	antagonist	Ki(nM) = 0.2
21	P35462_DB01184	n/a	DB01184	n/a	n/a	Domperidone	antagonist	Ki(nM) = 2.9
22	P35462_DB01186	n/a	DB01186	n/a	n/a	Pergolide	agonist	Ki(nM) = 2.3
23	P35462_08Y	08Y	DB01200	31101	CHEMBL493	Bromocriptine	agonist	Ki(nM) = 2.1
24	P35462_DB01224	n/a	DB01224	n/a	n/a	Quetiapine	ligand	Ki(nM) = 9.2
25	P35462_DAH	DAH	DB01235	6047;6971033;	CHEMBL1009	Levodopa	agonist
26	P35462_9SC	9SC	DB01238	60795	CHEMBL1112	Aripiprazole	antagonist	Ki(nM) = 0.8 EC50(nM) = 19.0
27	P35462_DB01239	n/a	DB01239	n/a	n/a	Chlorprothixene	antagonist
28	P35462_DB01267	n/a	DB01267	n/a	n/a	Paliperidone	antagonist	Ki(nM) = 0.1
29	P35462_DB01392	n/a	DB01392	n/a	n/a	Yohimbine	antagonist	Ki(nM) = 2489.0
30	P35462_DB01403	n/a	DB01403	n/a	n/a	Methotrimeprazine	antagonist
31	P35462_DB04946	n/a	DB04946	n/a	n/a	Iloperidone	antagonist	Ki(nM) = 7.1
32	P35462_DB05271	n/a	DB05271	n/a	n/a	Rotigotine	agonist
33	P35462_DB05766	n/a	DB05766	n/a	n/a	Norclozapine	n/a
34	P35462_7RU	7RU	DB06016	n/a	CHEMBL2028019	Cariprazine	partial agonist	Ki(nM) = 0.085 IC50(nM) = 0.89 EC50(nM) = 5.8
35	P35462_DB06148	n/a	DB06148	n/a	n/a	Mianserin	binder
36	P35462_DB06216	n/a	DB06216	n/a	n/a	Asenapine	antagonist	Ki(nM) = 1.8
37	P35462_DB06288	n/a	DB06288	n/a	n/a	Amisulpride	antagonist	Ki(nM) = 2.4
38	P35462_DB06454	n/a	DB06454	n/a	n/a	Sarizotan	ligand
39	P35462_DB06477	n/a	DB06477	n/a	n/a	Sumanirole	n/a
40	P35462_DB09014	n/a	DB09014	n/a	n/a	Captodiame	agonist
41	P35462_DB09207	n/a	DB09207	n/a	n/a	AS-8112	antagonist
42	P35462_DB09223	n/a	DB09223	n/a	n/a	Blonanserin	antagonist
43	P35462_DB09286	n/a	DB09286	n/a	n/a	Pipamperone	n/a	Ki(nM) = 250.0
44	P35462_DB09289	n/a	DB09289	n/a	n/a	Tianeptine	agonist
45	P35462_DB11274	n/a	DB11274	n/a	n/a	Dihydro-alpha-ergocryptine	partial agonist
46	P35462_DB12061	n/a	DB12061	n/a	n/a	Pardoprunox	n/a
47	P35462_DB12478	n/a	DB12478	n/a	n/a	Piribedil	agonist
48	P35462_DB13025	n/a	DB13025	n/a	n/a	Tiapride	blocker
49	P35462_DB14185	n/a	DB14185	n/a	n/a	Aripiprazole lauroxil	n/a