Gene name: FDFT1
Protein name: Squalene synthase (SQS)
List of molecules and drugs that interact with protein P37268
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P37268_8PH | 8PH | n/a | 71624067;137348737; | CHEMBL2338362 | hydrogen [(1R)-2-(3-decyl-1H-imidazol-3-ium-1-yl)-1-hydroxy-1-phosphonoethyl]phosphonate | n/a | |
| 2 | P37268_B65 | B65 | DB07420 | 24748047 | CHEMBL1207949 | (1R)-4-(3-phenoxyphenyl)-1-phosphonobutane-1-sulfonic acid | n/a | |
| 3 | P37268_BH3 | BH3 | n/a | 71624438;137349007; | CHEMBL2338383 | hydrogen [(1R)-2-(3-pentadecyl-1H-imidazol-3-ium-1-yl)-1-phosphonoethyl]phosphonate | n/a | |
| 4 | P37268_BH5 | BH5 | n/a | 71624187;137349008; | CHEMBL2338367 | hydrogen [(1R)-1-hydroxy-2-(3-pentadecyl-1H-imidazol-3-ium-1-yl)-1-phosphonoethyl]phosphonate | n/a | |
| 5 | P37268_BH8 | BH8 | n/a | 71624313;137349009; | CHEMBL2338378 | hydrogen [(1S)-2-(3-decyl-1H-imidazol-3-ium-1-yl)-1-phosphonoethyl]phosphonate | n/a | |
| 6 | P37268_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 7 | P37268_D3A | D3A | n/a | 57778011 | CHEMBL2057280 | (1-{[(4R,6S)-8-chloro-6-(2,3-dimethoxyphenyl)-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]acetyl}piperidin-4-yl)acetic acid | n/a | |
| 8 | P37268_D61 | D61 | n/a | 54669585 | n/a | (2R,3R)-2-(carboxymethoxy)-4-{[5-(naphthalen-2-yl)pentyl]amino}-3-{[5-(naphthalen-2-yl)pentyl]oxy}-4-oxobutanoic acid | n/a | |
| 9 | P37268_D99 | D99 | n/a | 54669582 | n/a | (3R)-1-{4-[{4-chloro-2-[(S)-(2-chlorophenyl)(hydroxy)methyl]phenyl}(2,2-dimethylpropyl)amino]-4-oxobutanoyl}piperidine-3-carboxylic acid | n/a | |
| 10 | P37268_D9A | D9A | n/a | 15481404 | n/a | N-{[(3R,5S)-7-chloro-5-(2,3-dimethoxyphenyl)-1-(2,2-dimethylpropyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]acetyl}-L-aspartic acid | n/a | |
| 11 | P37268_E5S | E5S | n/a | 44450555 | CHEMBL258717 | (3R)-3-({2-benzyl-6-[(3R,4S)-3-hydroxy-4-methoxypyrrolidin-1-yl]pyridin-3-yl}ethynyl)-1-azabicyclo[2.2.2]octan-3-ol | n/a | |
| 12 | P37268_ER4 | ER4 | n/a | 9844255 | CHEMBL258503 | (3R)-3-{[2-benzyl-6-(3-methoxypropoxy)pyridin-3-yl]ethynyl}-1-azabicyclo[2.2.2]octan-3-ol | n/a | |
| 13 | P37268_FPS | FPS | DB04695 | 657041 | n/a | S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE | n/a | |
| 14 | P37268_IN0 | IN0 | n/a | 445474 | n/a | N-{2-[TRANS-7-CHLORO-1-(2,2-DIMETHYL-PROPYL) -5-NAPHTHALEN-1-YL-2-OXO-1,2,3,5-TETRAHYDRO-BENZO[E] [1,4]OXAZEPIN-3-YL]-ACETYL}-ASPARTIC ACID | n/a | |
| 15 | P37268_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 16 | P37268_MN | MN | n/a | 27854 | n/a | MANGANESE (II) ION | n/a | |
| 17 | P37268_NI | NI | n/a | 934 | n/a | NICKEL (II) ION | n/a | |
| 18 | P37268_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 19 | P37268_PS7 | PS7 | n/a | 6449797 | n/a | {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate | n/a | |
| 20 | P37268_RWY | RWY | n/a | 10265208 | CHEMBL39581 | 2-(4-phenoxyphenoxy)ethyl thiocyanate | n/a | |
| 21 | P37268_RWZ | RWZ | n/a | n/a | n/a | N-[(2Z)-3,7-dimethylocta-2,6-dien-1-yl]-N'-[(1R,3S,5R,7R)-tricyclo[3.3.1.1~3,7~]dec-2-yl]ethane-1,2-diamine | n/a | |
| 22 | P37268_ZGA | ZGA | n/a | 6438355 | CHEMBL280978 | Zaragozic acid A | n/a |