Gene name: SLC19A1
Protein name: Reduced folate transporter
List of molecules and drugs that interact with protein P41440
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P41440_1SY | 1SY | n/a | 71563406;135564529; | CHEMBL4465054 | cGAMP | n/a | |
| 2 | P41440_2BA | 2BA | n/a | 11158091 | CHEMBL1229884 | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide | n/a | |
| 3 | P41440_AJP | AJP | n/a | 6474107 | n/a | Digitonin | n/a | |
| 4 | P41440_GJF | GJF | n/a | n/a | n/a | (1~{R},3~{S},6~{R},8~{R},9~{R},10~{S},12~{S},15~{R},17~{R},18~{R})-8,17-bis(6-aminopurin-9-yl)-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecane-9,18-diol | n/a | |
| 5 | P41440_LYA | LYA | DB00642 | 446556;5288715;135410875; | CHEMBL225072 | 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID | n/a | |
| 6 | P41440_MTX | MTX | DB00563 | 126941 | CHEMBL34259 | METHOTREXATE | modulator | Ki(nM) = 3500.0 IC50(nM) = 12.0 |
| 7 | P41440_THH | THH | DB11256 | 444412;5287865;135398561; | CHEMBL1231574 | N-[4-({[(6S)-2-AMINO-4-HYDROXY-5-METHYL-5,6,7,8-TETRAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC ACID | n/a |