Gene name: GRM5
Protein name: Metabotropic glutamate receptor
List of molecules and drugs that interact with protein P41594
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P41594_2U8 | 2U8 | DB13004 | 9926832 | CHEMBL3087515 | Mavoglurant | modulator | |
| 2 | P41594_4YI | 4YI | n/a | n/a | n/a | 2-chloranyl-~{N}-[2-methoxy-4-[(~{E})-pyridin-2-yldiazenyl]phenyl]benzamide | n/a | |
| 3 | P41594_51D | 51D | n/a | 86280685 | CHEMBL3603915 | 3-chloro-4-fluoro-5-[6-(1H-pyrazol-1-yl)pyrimidin-4-yl]benzonitrile | n/a | |
| 4 | P41594_51E | 51E | n/a | 86763358 | CHEMBL3603923 | 3-chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile | n/a | |
| 5 | P41594_D7W | D7W | DB12931 | 162834;135413554;135497698;135659063; | CHEMBL239800 | 1-(3-chlorophenyl)-3-(3-methyl-5-oxidanylidene-4~{H}-imidazol-2-yl)urea | allosteric modulator | |
| 6 | P41594_D8B | D8B | n/a | 5311462 | CHEMBL332397 | 2-[2-(3-methoxyphenyl)ethynyl]-6-methyl-pyridine | n/a | |
| 7 | P41594_GLU | GLU | DB00142 | 33032;44272391;88747398; | CHEMBL575060 | GLUTAMIC ACID | n/a | Ki(nM) = 390.0 EC50(nM) = 4100.0 |
| 8 | P41594_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 9 | P41594_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 10 | P41594_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 11 | P41594_OLA | OLA | n/a | 445639 | CHEMBL8659 | OLEIC ACID | n/a | |
| 12 | P41594_OLC | OLC | n/a | 11451146 | n/a | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | n/a | |
| 13 | P41594_QUS | QUS | DB02999 | 40539;6971145; | CHEMBL279956 | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID | inhibitor | Ki(nM) = 29.0 EC50(nM) = 150.0 |
| 14 | P41594_Y01 | Y01 | n/a | 65082 | n/a | CHOLESTEROL HEMISUCCINATE | n/a | |
| 15 | P41594_YKU | YKU | n/a | 11245456 | CHEMBL190270 | 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide | n/a | |
| 16 | P41594_Z99 | Z99 | n/a | 9819927 | CHEMBL432038 | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine | n/a | |
| 17 | P41594_DB00659 | n/a | DB00659 | n/a | n/a | Acamprosate | antagonist | |
| 18 | P41594_DB06201 | n/a | DB06201 | n/a | n/a | Rufinamide | inhibitor | |
| 19 | P41594_DB12733 | n/a | DB12733 | n/a | n/a | Dipraglurant | modulator |