Gene name: HTR2B
Protein name: 5-hydroxytryptamine receptor 2B
List of molecules and drugs that interact with protein P41595
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P41595_7LD | 7LD | DB04829 | 5761 | CHEMBL263881 | (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide | agonist | Ki(nM) = 0.42 |
| 2 | P41595_CLR | CLR | DB04540 | 5997 | CHEMBL112570 | CHOLESTEROL | n/a | |
| 3 | P41595_DGA | DGA | n/a | 9543705 | n/a | DIACYL GLYCEROL | n/a | |
| 4 | P41595_ERM | ERM | DB00696 | 8223 | CHEMBL442 | Ergotamine | n/a | Ki(nM) = 3.0 |
| 5 | P41595_H8D | H8D | DB00353 | 8226 | CHEMBL1201356 | (8beta)-N-[(2S)-1-hydroxybutan-2-yl]-6-methyl-9,10-didehydroergoline-8-carboxamide | n/a | Ki(nM) = 0.49 |
| 6 | P41595_H8G | H8G | DB00589 | 28864 | CHEMBL157138 | N,N-diethyl-N'-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea | antagonist | Ki(nM) = 1.1 |
| 7 | P41595_H8J | H8J | n/a | 9681 | CHEMBL1065 | (8alpha)-N-[(2S)-1-hydroxybutan-2-yl]-1,6-dimethyl-9,10-didehydroergoline-8-carboxamide | n/a | |
| 8 | P41595_H8M | H8M | n/a | 92460087 | n/a | (1S)-1-[(2-chloro-3,4-dimethoxyphenyl)methyl]-6-methyl-2,3,4,9-tetrahydro-1H-beta-carboline | n/a | |
| 9 | P41595_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 10 | P41595_OLA | OLA | n/a | 445639 | CHEMBL8659 | OLEIC ACID | n/a | |
| 11 | P41595_OLB | OLB | n/a | 12178130 | n/a | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | n/a | |
| 12 | P41595_OLC | OLC | n/a | 11451146 | n/a | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | n/a | |
| 13 | P41595_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 14 | P41595_PLM | PLM | DB03796 | 985;135369651; | CHEMBL82293 | PALMITIC ACID | n/a | |
| 15 | P41595_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 16 | P41595_TRS | TRS | DB03754 | 3777159;88088752;152743085; | n/a | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 17 | P41595_DB00247 | n/a | DB00247 | n/a | n/a | Methysergide | antagonist | |
| 18 | P41595_DB00248 | n/a | DB00248 | n/a | n/a | Cabergoline | agonist | Ki(nM) = 1.4 EC50(nM) = 13.0 |
| 19 | P41595_DB00315 | n/a | DB00315 | n/a | n/a | Zolmitriptan | agonist | |
| 20 | P41595_2GM | 2GM | DB00320 | 10531 | CHEMBL1732 | Dihydroergotamine | agonist | Ki(nM) = 3.7 |
| 21 | P41595_C7H | C7H | DB00434 | 2913 | CHEMBL516 | Cyproheptadine | antagonist | Ki(nM) = 1.5 |
| 22 | P41595_DB00508 | n/a | DB00508 | n/a | n/a | Triflupromazine | antagonist | |
| 23 | P41595_DB00543 | n/a | DB00543 | n/a | n/a | Amoxapine | antagonist | |
| 24 | P41595_DB00574 | n/a | DB00574 | n/a | n/a | Fenfluramine | agonist | Ki(nM) = 400.0 |
| 25 | P41595_OR9 | OR9 | DB00714 | 6005 | CHEMBL53 | Apomorphine | agonist | Ki(nM) = 131.83 |
| 26 | P41595_8PR | 8PR | DB00715 | 43815 | CHEMBL490 | Paroxetine | agonist | Ki(nM) = 10000.0 |
| 27 | P41595_DB00805 | n/a | DB00805 | n/a | n/a | Minaprine | antagonist | |
| 28 | P41595_DB00924 | n/a | DB00924 | n/a | n/a | Cyclobenzaprine | antagonist | |
| 29 | P41595_DB01079 | n/a | DB01079 | n/a | n/a | Tegaserod | antagonist | |
| 30 | P41595_DB01142 | no_lig_id | DB01142 | n/a | n/a | Doxepin | antagonist | |
| 31 | P41595_DB01186 | n/a | DB01186 | n/a | n/a | Pergolide | agonist | Ki(nM) = 7.08 |
| 32 | P41595_08Y | 08Y | DB01200 | 31101 | CHEMBL493 | Bromocriptine | agonist | Ki(nM) = 56.23 |
| 33 | P41595_9SC | 9SC | DB01238 | 60795 | CHEMBL1112 | Aripiprazole | inverse agonist | Ki(nM) = 0.36 |
| 34 | P41595_CXX | CXX | DB01242 | 2801 | CHEMBL415 | Clomipramine | antagonist | |
| 35 | P41595_DB01392 | n/a | DB01392 | n/a | n/a | Yohimbine | antagonist | Ki(nM) = 4.12 |
| 36 | P41595_DB01454 | n/a | DB01454 | n/a | n/a | Midomafetamine | agonist | Ki(nM) = 500.0 |
| 37 | P41595_DB05461 | n/a | DB05461 | n/a | n/a | OPC-28326 | n/a | |
| 38 | P41595_NP1 | NP1 | DB05492 | 5276854 | CHEMBL609728 | Epicept NP-1 | n/a | |
| 39 | P41595_DB05607 | n/a | DB05607 | n/a | n/a | PRX-08066 | antagonist | |
| 40 | P41595_7RU | 7RU | DB06016 | n/a | CHEMBL2028019 | Cariprazine | antagonist | Ki(nM) = 0.151 |
| 41 | P41595_DB06148 | n/a | DB06148 | n/a | n/a | Mianserin | binder | |
| 42 | P41595_DB06153 | n/a | DB06153 | n/a | n/a | Pizotifen | antagonist | |
| 43 | P41595_DB06216 | n/a | DB06216 | n/a | n/a | Asenapine | antagonist | Ki(nM) = 0.21 |
| 44 | P41595_DB06229 | n/a | DB06229 | n/a | n/a | Ocaperidone | n/a | |
| 45 | P41595_DB09185 | n/a | DB09185 | n/a | n/a | Viloxazine | antagonist | |
| 46 | P41595_DB09286 | n/a | DB09286 | n/a | n/a | Pipamperone | n/a | Ki(nM) = 47.4 |