Gene name: GRIA2
Protein name: Glutamate receptor 2
List of molecules and drugs that interact with protein P42262
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P42262_08W | 08W | n/a | 54759161 | CHEMBL1940324 | N-methyl-1-{3-[(methylsulfonyl)amino]-2,4-dioxo-7-(trifluoromethyl)-1,2,3,4-tetrahydroquinazolin-6-yl}-1H-imidazole-4-carboxamide | n/a | |
| 2 | P42262_0YK | 0YK | DB16304 | 56655833 | CHEMBL4594403 | 7-(4-cyclohexyloxyphenyl)-9-methyl-4$l^{6}-thia-1$l^{4},5,8-triazabicyclo[4.4.0]deca-1(10),6,8-triene 4,4-dioxide | n/a | |
| 3 | P42262_5YC | 5YC | n/a | 20938953 | CHEMBL3797274 | 7-[[ethyl(phenyl)amino]methyl]-2-methyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one | n/a | |
| 4 | P42262_7T9 | 7T9 | n/a | 46398805 | CHEMBL1214399 | N-[(2S)-5-(6-FLUORO-3-PYRIDINYL)-2,3-DIHYDRO-1H-INDEN-2-YL]-2-PROPANESULFONAMIDE | n/a | |
| 5 | P42262_8SO | 8SO | DB12717 | 9889366 | CHEMBL1277001 | N-[(2R)-2-[4-[4-[2-(methylsulfonylamino)ethyl]phenyl]phenyl]propyl]propane-2-sulfonamide | n/a | |
| 6 | P42262_8SR | 8SR | n/a | 1222102 | n/a | 2-[2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]ethanoylamino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide | n/a | |
| 7 | P42262_9C0 | 9C0 | n/a | 66748417 | n/a | 9-(4-~{tert}-butylphenyl)-3,4-dihydropyrido[2,1-c][1,2,4]thiadiazine 2,2-dioxide | n/a | |
| 8 | P42262_9C3 | 9C3 | n/a | 66747896 | n/a | 9-{4-[(propan-2-yl)oxy]phenyl}-3,4-dihydro-2H-2lambda~6~-pyrido[2,1-c][1,2,4]thiadiazine-2,2-dione | n/a | |
| 9 | P42262_9C6 | 9C6 | n/a | 56649286 | n/a | 9-(4-phenoxyphenyl)-3,4-dihydro-2H-2lambda~6~-pyrido[2,1-c][1,2,4]thiadiazine-2,2-dione | n/a | |
| 10 | P42262_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 11 | P42262_CAC | CAC | n/a | 167250 | n/a | CACODYLATE ION | n/a | |
| 12 | P42262_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 13 | P42262_GLU | GLU | DB00142 | 33032;44272391;88747398; | CHEMBL575060 | GLUTAMIC ACID | n/a | Ki(nM) = 940.0 EC50(nM) = 2190.0 |
| 14 | P42262_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 15 | P42262_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 16 | P42262_QSN | QSN | n/a | 11646308 | CHEMBL1738879 | N-[6-(1H-imidazol-1-yl)-7-nitro-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl]methanesulfonamide | n/a | |
| 17 | P42262_RN8 | RN8 | n/a | 52914872 | n/a | 3,3'-benzene-1,4-diylbis(4-cyano-5-ethylthiophene-2-carboxylic acid) | n/a | |
| 18 | P42262_RNN | RNN | n/a | 9969799 | n/a | N,N'-(benzene-1,4-diyldiethane-2,1-diyl)dipropane-2-sulfonamide | n/a | |
| 19 | P42262_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 20 | P42262_ZK1 | ZK1 | DB12393 | 208953 | CHEMBL19892 | {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | n/a | |
| 21 | P42262_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 22 | P42262_GGL | GGL | DB00142 | 33032;44272391;88747398; | CHEMBL575060 | Glutamic acid | n/a | Ki(nM) = 940.0 EC50(nM) = 2190.0 |
| 23 | P42262_DB00237 | n/a | DB00237 | n/a | n/a | Butabarbital | antagonist | |
| 24 | P42262_DB00241 | n/a | DB00241 | n/a | n/a | Butalbital | antagonist | |
| 25 | P42262_DB00306 | n/a | DB00306 | n/a | n/a | Talbutal | antagonist | |
| 26 | P42262_DB00312 | n/a | DB00312 | n/a | n/a | Pentobarbital | antagonist | |
| 27 | P42262_DB00418 | n/a | DB00418 | n/a | n/a | Secobarbital | antagonist | |
| 28 | P42262_VOK | VOK | DB00463 | 4099 | CHEMBL450 | Metharbital | antagonist | |
| 29 | P42262_DB00599 | n/a | DB00599 | n/a | n/a | Thiopental | antagonist | |
| 30 | P42262_DB00794 | n/a | DB00794 | n/a | n/a | Primidone | antagonist | |
| 31 | P42262_DB00849 | n/a | DB00849 | n/a | n/a | Methylphenobarbital | antagonist | |
| 32 | P42262_EOH | EOH | DB00898 | 702 | CHEMBL545 | Ethanol | n/a | |
| 33 | P42262_UQA | UQA | DB01174 | 4763 | CHEMBL40 | Phenobarbital | antagonist | |
| 34 | P42262_DB01346 | n/a | DB01346 | n/a | n/a | Quinidine barbiturate | antagonist | |
| 35 | P42262_DB01351 | n/a | DB01351 | n/a | n/a | Amobarbital | antagonist | |
| 36 | P42262_DB01352 | n/a | DB01352 | n/a | n/a | Aprobarbital | antagonist | |
| 37 | P42262_DB01353 | n/a | DB01353 | n/a | n/a | Butobarbital | antagonist | |
| 38 | P42262_DB01354 | n/a | DB01354 | n/a | n/a | Heptabarbital | antagonist | |
| 39 | P42262_DB01355 | n/a | DB01355 | n/a | n/a | Hexobarbital | antagonist | |
| 40 | P42262_DB01483 | n/a | DB01483 | n/a | n/a | Barbital | antagonist | |
| 41 | P42262_DB01496 | n/a | DB01496 | n/a | n/a | Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione | antagonist | |
| 42 | P42262_SHI | SHI | DB01664 | 447195 | n/a | (S)-DES-ME-AMPA | n/a | |
| 43 | P42262_AMQ | AMQ | DB02057 | 158397;7000183; | CHEMBL276815 | (S)-AMPA | n/a | |
| 44 | P42262_AT1 | AT1 | DB02347 | 447249 | CHEMBL594840 | 2-Amino-3-(5-Tert-Butyl-3-(Phosphonomethoxy)-4-Isoxazolyl)Propionic Acid | n/a | |
| 45 | P42262_IWD | IWD | DB02818 | 447196 | CHEMBL121915 | Iodo-Willardiine | n/a | Ki(nM) = 176.0 |
| 46 | P42262_FWD | FWD | DB02966 | 126569 | CHEMBL123132 | Fluoro-Willardiine | agonist | Ki(nM) = 25.0 EC50(nM) = 463.0 |
| 47 | P42262_QUS | QUS | DB02999 | 40539;6971145; | CHEMBL279956 | Quisqualic acid | n/a | |
| 48 | P42262_CPW | CPW | DB03240 | 657004 | CHEMBL337577 | (S)-2-Amino-3-(1,3,5,7-Pentahydro-2,4-Dioxo-Cyclopenta[E]Pyrimidin-1-Yl) Proionic Acid | n/a | |
| 49 | P42262_CE2 | CE2 | DB03319 | 5287901;131704239; | n/a | (2S)-2-Ammonio-3-[5-(2-methyl-2-propanyl)-3-oxido-1,2-oxazol-4-yl]propanoate | n/a | |
| 50 | P42262_DB03759 | n/a | DB03759 | n/a | n/a | FG-9041 | n/a | |
| 51 | P42262_BWD | BWD | DB04000 | 167842 | CHEMBL333964 | Bromo-Willardiine | n/a | Ki(nM) = 101.0 |
| 52 | P42262_HWD | HWD | DB04129 | 440053;25200769; | CHEMBL122005 | Willardiine | n/a | Ki(nM) = 898.0 |
| 53 | P42262_IBC | IBC | DB04152 | 5288598 | CHEMBL28472 | 2-Amino-3-(3-Hydroxy-7,8-Dihydro-6h-Cyclohepta[D]-4-Isoxazolyl)Propionic Acid | n/a | |
| 54 | P42262_4MP | 4MP | DB04599 | 2196 | CHEMBL36994 | Aniracetam | n/a | |
| 55 | P42262_U1K | U1K | DB04798 | 5289517;5289518; | CHEMBL29024 | THIO-ATPA | n/a | |
| 56 | P42262_DB04982 | n/a | DB04982 | n/a | n/a | Talampanel | n/a | |
| 57 | P42262_DB05047 | n/a | DB05047 | n/a | n/a | CX-717 | n/a | |
| 58 | P42262_BHY | BHY | DB07455 | 22489160 | n/a | N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dimethanesulfonamide | n/a | |
| 59 | P42262_CX6 | CX6 | DB07598 | 5288002 | n/a | 2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE | n/a | |
| 60 | P42262_NS3 | NS3 | DB08303 | 44129629 | n/a | (3S)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide | n/a | |
| 61 | P42262_NS6 | NS6 | DB08304 | 44129630 | n/a | (3R)-3-cyclopentyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide | n/a | |
| 62 | P42262_NS7 | NS7 | DB08305 | 44129631 | n/a | (3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide | n/a | |
| 63 | P42262_DB13146 | n/a | DB13146 | n/a | n/a | Fluciclovine (18F) | inhibitor |