Gene name: MTOR
Protein name: Serine/threonine-protein kinase mTOR
List of molecules and drugs that interact with protein P42345
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P42345_0AN | 0AN | n/a | 168451627 | n/a | (1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-[(~{E})-2-(2-chlorophenyl)ethenyl]-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 2 | P42345_17G | 17G | n/a | 51358113 | CHEMBL1765602 | 9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2(1H)-one | n/a | |
| 3 | P42345_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 4 | P42345_ADP | ADP | DB16833 | 6022 | CHEMBL14830 | ADENOSINE-5'-DIPHOSPHATE | n/a | |
| 5 | P42345_AGS | AGS | DB02930 | 440317;444377; | CHEMBL131890 | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | n/a | |
| 6 | P42345_ARD | ARD | n/a | 6323222 | CHEMBL263850 | C15-(R)-METHYLTHIENYL RAPAMYCIN | n/a | |
| 7 | P42345_ATP | ATP | DB00171 | 5957 | CHEMBL14249 | ADENOSINE-5'-TRIPHOSPHATE | n/a | |
| 8 | P42345_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 9 | P42345_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 10 | P42345_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 11 | P42345_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 12 | P42345_MGF | MGF | n/a | 447728;5496785; | n/a | TRIFLUOROMAGNESATE | n/a | |
| 13 | P42345_P2X | P2X | n/a | 135565635 | CHEMBL1241674 | 2-[4-amino-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol | n/a | |
| 14 | P42345_RAD | RAD | n/a | 5289261 | CHEMBL4287588 | C49-METHYL RAPAMYCIN | n/a | |
| 15 | P42345_RAP | RAP | DB00877 | 5284616 | CHEMBL413 | RAPAMYCIN IMMUNOSUPPRESSANT DRUG | inhibitor | |
| 16 | P42345_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 17 | P42345_X6K | X6K | DB17046 | 9884685 | CHEMBL573339 | 3-(4-MORPHOLIN-4-YLPYRIDO[3',2':4,5]FURO[3,2-D]PYRIMIDIN-2-YL)PHENOL | n/a | |
| 18 | P42345_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 19 | P42345_DB00337 | n/a | DB00337 | n/a | n/a | Pimecrolimus | potentiator | |
| 20 | P42345_DB01590 | n/a | DB01590 | n/a | n/a | Everolimus | inhibitor | |
| 21 | P42345_DB04974 | n/a | DB04974 | n/a | n/a | Rimiducid | ligand | |
| 22 | P42345_DB06233 | n/a | DB06233 | n/a | n/a | Ridaforolimus | inhibitor | |
| 23 | P42345_A4I | A4I | DB06287 | 6918289 | CHEMBL1201182 | Temsirolimus | inhibitor | IC50(nM) = 1760.0 |
| 24 | P42345_DB11962 | n/a | DB11962 | n/a | n/a | GSK-1059615 | inhibitor | |
| 25 | P42345_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor | |
| 26 | P42345_DB12843 | n/a | DB12843 | n/a | n/a | Oleandrin | downregulator |