Gene name: ABL2
Protein name: Tyrosine-protein kinase ABL2
List of molecules and drugs that interact with protein P42684
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P42684_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 2 | P42684_DKI | DKI | DB07664 | 5330812 | CHEMBL261720 | 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE | n/a | |
| 3 | P42684_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 4 | P42684_VX6 | VX6 | n/a | 5494449 | CHEMBL572878 | CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE | n/a | |
| 5 | P42684_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 6 | P42684_STI | STI | DB00619 | 5291 | CHEMBL941 | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE | n/a | IC50(nM) = 272.0 Kd(nM) = 10.0 |
| 7 | P42684_ATP | ATP | DB00171 | 5957 | CHEMBL14249 | ATP | inhibitor | |
| 8 | P42684_1N1 | 1N1 | DB01254 | 3062316 | CHEMBL1421 | Dasatinib | multitarget | IC50(nM) = 2100.0 Kd(nM) = 0.17 |
| 9 | P42684_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |