Gene name: PTGFR
Protein name: Prostaglandin F2-alpha receptor
List of molecules and drugs that interact with protein P43088
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P43088_7WT | 7WT | DB19360 | 6441636 | CHEMBL1050 | Z-7-[(1R,2R,3R,5S)-3,5-bis(oxidanyl)-2-[(3R)-3-oxidanyl-5-phenyl-pentyl]cyclopentyl]hept-5-enoic acid | n/a | |
| 2 | P43088_S2F | S2F | n/a | 9978917 | CHEMBL5315132 | (~{Z})-7-[(1~{R},2~{R},3~{R},5~{S})-2-[(~{E})-3,3-bis(fluoranyl)-4-phenoxy-but-1-enyl]-3,5-bis(oxidanyl)cyclopentyl]hept-5-enoic acid | n/a | |
| 3 | P43088_UGU | UGU | DB12789 | 5280363 | CHEMBL815 | (Z)-7-[(1R,2R,3R,5S)-3,5-bis(oxidanyl)-2-[(E,3S)-3-oxidanyloct-1-enyl]cyclopentyl]hept-5-enoic acid | agonist | |
| 4 | P43088_DB00287 | n/a | DB00287 | n/a | n/a | Travoprost | agonist | |
| 5 | P43088_DB00654 | n/a | DB00654 | n/a | n/a | Latanoprost | agonist | Ki(nM) = 2.8 |
| 6 | P43088_15M | 15M | DB00905 | 5311027 | CHEMBL1200963 | Bimatoprost | agonist | |
| 7 | P43088_DB01160 | n/a | DB01160 | n/a | n/a | Dinoprost tromethamine | agonist | Ki(nM) = 119.0 IC50(nM) = 2.5 EC50(nM) = 24.5 |
| 8 | P43088_DB08819 | n/a | DB08819 | n/a | n/a | Tafluprost | agonist | |
| 9 | P43088_DB11660 | n/a | DB11660 | n/a | n/a | Latanoprostene bunod | agonist |