Gene name: PTGER2
Protein name: Prostaglandin E2 receptor
List of molecules and drugs that interact with protein P43116
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P43116_GM9 | GM9 | DB12022 | 9890801 | CHEMBL563646 | 2-[3-[[(4-~{tert}-butylphenyl)methyl-pyridin-3-ylsulfonyl-amino]methyl]phenoxy]ethanoic acid | agonist | |
| 2 | P43116_GNO | GNO | DB12623 | 18376177 | CHEMBL2107783 | 2-[3-[[(4-pyrazol-1-ylphenyl)methyl-pyridin-3-ylsulfonyl-amino]methyl]phenoxy]ethanoic acid | agonist | |
| 3 | P43116_P2E | P2E | DB00917 | 5280360 | CHEMBL548 | (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid | agonist | Ki(nM) = 1.0 IC50(nM) = 2.6 EC50(nM) = 1.9 |
| 4 | P43116_DB00374 | n/a | DB00374 | n/a | n/a | Treprostinil | agonist | |
| 5 | P43116_XPG | XPG | DB00770 | 5280723 | CHEMBL495 | Alprostadil | agonist | |
| 6 | P43116_DB00929 | n/a | DB00929 | n/a | n/a | Misoprostol | agonist | Ki(nM) = 34.0 |
| 7 | P43116_DB08964 | n/a | DB08964 | n/a | n/a | Gemeprost | agonist | |
| 8 | P43116_DB09211 | n/a | DB09211 | n/a | n/a | Limaprost | agonist | |
| 9 | P43116_DB15071 | n/a | DB15071 | n/a | n/a | Omidenepag isopropyl | agonist |