Gene name: NAMPT
Protein name: Nicotinamide phosphoribosyltransferase (NAmPRTase)
List of molecules and drugs that interact with protein P43490
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P43490_1EB | 1EB | n/a | 2921832 | CHEMBL3127517 | N-(4-nitrophenyl)cyclopropanecarboxamide | n/a | |
| 2 | P43490_1LJ | 1LJ | n/a | 66610926 | CHEMBL2393183 | 1-[(6-aminopyridin-3-yl)methyl]-3-[4-(phenylsulfonyl)phenyl]urea | n/a | |
| 3 | P43490_1LS | 1LS | n/a | 317146;2803102; | CHEMBL1586371 | 1-[4-(piperidin-1-ylsulfonyl)phenyl]-3-(pyridin-3-ylmethyl)thiourea | n/a | |
| 4 | P43490_1QR | 1QR | n/a | 66610019 | CHEMBL2420670 | N-[4-(piperidin-1-ylsulfonyl)benzyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxamide | n/a | |
| 5 | P43490_1QS | 1QS | n/a | 68277611 | CHEMBL2420629 | N-{4-[(3,5-difluorophenyl)sulfonyl]benzyl}imidazo[1,2-a]pyridine-6-carboxamide | n/a | |
| 6 | P43490_1R7 | 1R7 | n/a | 71656170 | n/a | N-(4-{[1-(tetrahydro-2H-pyran-4-yl)piperidin-4-yl]sulfonyl}benzyl)-2H-pyrrolo[3,4-c]pyridine-2-carboxamide | n/a | |
| 7 | P43490_1XC | 1XC | n/a | 74331704 | n/a | 6-({4-[(3,5-difluorophenyl)sulfonyl]benzyl}carbamoyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)imidazo[1,2-a]pyridin-1-ium | n/a | |
| 8 | P43490_1XD | 1XD | n/a | 66611965 | n/a | N-{4-[(3,5-difluorophenyl)sulfonyl]benzyl}imidazo[1,2-a]pyridine-7-carboxamide | n/a | |
| 9 | P43490_20J | 20J | DB01119 | 3019 | CHEMBL181 | 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide | n/a | |
| 10 | P43490_20M | 20M | n/a | 76336446;136241658; | CHEMBL3127515 | N-(4-{[4-(pyrrolidin-1-yl)piperidin-1-yl]sulfonyl}benzyl)-2H-pyrido[4,3-e][1,2,4]thiadiazin-3-amine 1,1-dioxide | n/a | |
| 11 | P43490_20N | 20N | n/a | 310169 | CHEMBL3127516 | N-[4-(acetylamino)phenyl]cyclopropanecarboxamide | n/a | |
| 12 | P43490_20O | 20O | n/a | 71720911 | CHEMBL3127521 | (1S,2S)-N-[4-(phenylsulfonyl)phenyl]-2-(pyridin-3-yl)cyclopropanecarboxamide | n/a | |
| 13 | P43490_20P | 20P | n/a | 887836 | n/a | (1S,2S)-2-phenyl-N-(pyridin-4-yl)cyclopropanecarboxamide | n/a | |
| 14 | P43490_20R | 20R | n/a | 66610004 | CHEMBL3260347 | N-[4-(phenylsulfonyl)benzyl]-2H-pyrazolo[3,4-b]pyridine-5-carboxamide | n/a | |
| 15 | P43490_20T | 20T | n/a | 71720914 | n/a | 1-(5-O-phosphono-beta-D-ribofuranosyl)-N-(4-{[3-(trifluoromethyl)phenyl]sulfonyl}benzyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide | n/a | |
| 16 | P43490_2HH | 2HH | n/a | 649594 | CHEMBL1494030 | 1-methyl-N-(pyridin-3-yl)-1H-pyrazole-5-carboxamide | n/a | |
| 17 | P43490_2HJ | 2HJ | DB16761 | 984333 | CHEMBL3105156 | 4-({[(4-tert-butylphenyl)sulfonyl]amino}methyl)-N-(pyridin-3-yl)benzamide | n/a | |
| 18 | P43490_2HL | 2HL | n/a | 72771099 | CHEMBL3116399 | 1-[(1-benzoylpiperidin-4-yl)methyl]-N-(pyridin-3-yl)-1H-benzimidazole-5-carboxamide | n/a | |
| 19 | P43490_2P1 | 2P1 | n/a | 66613669 | CHEMBL3260358 | N-(4-{[3-(trifluoromethyl)phenyl]sulfonyl}benzyl)-2H-pyrazolo[3,4-b]pyridine-5-carboxamide | n/a | |
| 20 | P43490_2QF | 2QF | n/a | 76401548 | n/a | N-{4-[(3,5-difluorophenyl)sulfonyl]benzyl}indolizine-7-carboxamide | n/a | |
| 21 | P43490_2QG | 2QG | DB12980 | 148198 | CHEMBL17289 | 2-[6-(4-chlorophenoxy)hexyl]-1-cyano-3-pyridin-4-ylguanidine | inhibitor | |
| 22 | P43490_2RM | 2RM | n/a | 76401547 | n/a | N-{4-[(3,5-difluorophenyl)sulfonyl]benzyl}indolizine-6-carboxamide | n/a | |
| 23 | P43490_2ZM | 2ZM | n/a | 7195;86262143; | CHEMBL164921 | 5-nitro-1H-benzimidazole | n/a | |
| 24 | P43490_3TQ | 3TQ | n/a | 87057583 | n/a | N-(4-{(S)-[1-(2-methylpropyl)piperidin-4-yl]sulfinyl}benzyl)furo[2,3-c]pyridine-2-carboxamide | n/a | |
| 25 | P43490_6TA | 6TA | n/a | 121499158 | CHEMBL3948584 | ~{tert}-butyl (2~{S})-2-[(1,3-dihydropyrrolo[3,4-c]pyridin-2-ylcarbonylamino)methyl]-6-azaspiro[2.5]octane-6-carboxylate | n/a | |
| 26 | P43490_7A0 | 7A0 | n/a | 131704427 | n/a | [(2~{R},3~{S},4~{R},5~{R})-5-[2-azanyl-5-[[[4-[6-(ethylamino)-5-(2-piperidin-1-ylethylcarbamoyl)pyridin-2-yl]-2-fluoranyl-phenyl]carbamoylamino]methyl]pyridin-1-ium-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate | n/a | |
| 27 | P43490_7A1 | 7A1 | n/a | 46917091 | n/a | 6-[4-[(6-azanylpyridin-3-yl)methylcarbamoylamino]-3-fluoranyl-phenyl]-2-(ethylamino)-~{N}-(2-piperidin-1-ylethyl)pyridine-3-carboxamide | n/a | |
| 28 | P43490_7T7 | 7T7 | n/a | 57510027 | CHEMBL3929298 | N-[4-({[(3S)-oxolan-3-yl]methyl}carbamoyl)phenyl]-1,3-dihydro-2H-isoindole-2-carboxamide | n/a | |
| 29 | P43490_7TA | 7TA | n/a | 129010129 | n/a | N-{4-[1-(2-methylpropanoyl)piperidin-4-yl]phenyl}-2H-pyrrolo[3,4-c]pyridine-2-carboxamide | n/a | |
| 30 | P43490_7YE | 7YE | n/a | 139369460 | n/a | N-[4-[(5R)-6-oxidanylidene-5-quinolin-5-yl-5-(trifluoromethyl)-1,4-dihydropyridazin-3-yl]phenyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide | n/a | |
| 31 | P43490_7YK | 7YK | n/a | 163359796 | n/a | N-[4-[(4R)-4-methyl-1-(oxan-4-yl)-6-oxidanylidene-4,5-dihydropyridazin-3-yl]phenyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide | n/a | |
| 32 | P43490_7YT | 7YT | n/a | 134515694 | n/a | N-[4-[(4R)-1,4-dimethyl-6-oxidanylidene-4,5-dihydropyridazin-3-yl]phenyl]-5,7-dihydropyrrolo[3,4-b]pyridine-6-carboxamide | n/a | |
| 33 | P43490_7YX | 7YX | n/a | 163359797 | n/a | N-[4-[(4R)-1-cyclopentyl-4-methyl-6-oxidanylidene-4,5-dihydropyridazin-3-yl]phenyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide | n/a | |
| 34 | P43490_7Z2 | 7Z2 | n/a | 163359798 | n/a | N-[4-[(5R)-1-(4-azanylbutyl)-6-oxidanylidene-5-quinolin-5-yl-4,5-dihydropyridazin-3-yl]phenyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide | n/a | |
| 35 | P43490_8HV | 8HV | n/a | 129010134 | n/a | 5-fluoro-N-{4-[1-(2-hydroxy-2-methylpropanoyl)piperidin-4-yl]phenyl}-2H-isoindole-2-carboxamide | n/a | |
| 36 | P43490_8HY | 8HY | n/a | 129010133 | n/a | N-{4-[(3-phenylpropyl)carbamoyl]phenyl}-2H-isoindole-2-carboxamide | n/a | |
| 37 | P43490_96Q | 96Q | DB19243 | 117779453 | CHEMBL4297467 | (~{E})-3-(6-azanylpyridin-3-yl)-~{N}-[[5-[4-[4,4-bis(fluoranyl)piperidin-1-yl]carbonylphenyl]-7-(4-fluorophenyl)-1-benzofuran-2-yl]methyl]prop-2-enamide | n/a | |
| 38 | P43490_A12 | A12 | DB03148 | 92199 | CHEMBL583969 | PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | n/a | |
| 39 | P43490_AOY | AOY | n/a | 131955128 | CHEMBL4209934 | (3E)-3-[(phenylamino)methylidene]oxan-2-one | n/a | |
| 40 | P43490_AQ1 | AQ1 | n/a | 7539905;135567364; | CHEMBL4210011 | 2-[(2-fluorophenyl)amino]-6-propylpyrimidin-4(3H)-one | n/a | |
| 41 | P43490_BEF | BEF | n/a | 152255;3465631;23624244; | n/a | BERYLLIUM TRIFLUORIDE ION | n/a | |
| 42 | P43490_BWA | BWA | n/a | 134814219 | CHEMBL4206641 | N-{4-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-N'-[(pyridin-3-yl)methyl]urea | n/a | |
| 43 | P43490_C5V | C5V | n/a | 134814226 | CHEMBL4205098 | (1S,2S)-N-{4-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-(pyridin-3-yl)cyclopropane-1-carboxamide | n/a | |
| 44 | P43490_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 45 | P43490_CVJ | CVJ | n/a | 134817505 | CHEMBL4215840 | (1S,2S)-N-{4-[(1S)-1-(propanoylamino)ethyl]phenyl}-2-(pyridin-3-yl)cyclopropane-1-carboxamide | n/a | |
| 46 | P43490_CVP | CVP | n/a | 134817504 | CHEMBL4209227 | 4-[(piperazin-1-yl)methyl]-N-{[4-({[(pyridin-3-yl)methyl]carbamoyl}amino)phenyl]methyl}benzamide | n/a | |
| 47 | P43490_DGB | DGB | DB12731 | 6914657 | CHEMBL566757 | (2E)-N-{4-[1-(benzenecarbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide | inhibitor | |
| 48 | P43490_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 49 | P43490_DPO | DPO | n/a | 644102 | n/a | DIPHOSPHATE | n/a | |
| 50 | P43490_DTT | DTT | DB04447 | 439196 | CHEMBL406270 | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | n/a | |
| 51 | P43490_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 52 | P43490_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 53 | P43490_HVM | HVM | n/a | 134458913 | n/a | (2E)-N-{4-[1-(3-aminobenzene-1-carbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide | n/a | |
| 54 | P43490_J7F | J7F | n/a | 2975850 | CHEMBL5198222 | 2-(2-~{tert}-butylphenoxy)-~{N}-(4-hydroxyphenyl)ethanamide | n/a | |
| 55 | P43490_LTS | LTS | n/a | 56929167 | CHEMBL3098609 | 2-cyano-1-pyridin-4-yl-3-(4-{[3-(trifluoromethoxy)phenyl]sulfonyl}benzyl)guanidine | n/a | |
| 56 | P43490_LWW | LWW | n/a | 66609622 | CHEMBL2419503 | N-(4-(phenylsulfonyl)benzyl)-1H-pyrrolo[3,2-c]pyridine-2-carboxamide | n/a | |
| 57 | P43490_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 58 | P43490_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 59 | P43490_NCA | NCA | DB02701 | 936 | CHEMBL1140 | NICOTINAMIDE | n/a | |
| 60 | P43490_NCN | NCN | DB02382 | 121991;5288991; | n/a | NICOTINATE MONONUCLEOTIDE | n/a | |
| 61 | P43490_NIO | NIO | DB00627 | 938;117629482; | CHEMBL573 | NICOTINIC ACID | n/a | |
| 62 | P43490_NMN | NMN | DB03227 | 14181 | n/a | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE | n/a | |
| 63 | P43490_OE4 | OE4 | n/a | 145704651 | CHEMBL4546918 | N-{4-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-3-(pyridin-3-yl)azetidine-1-carboxamide | n/a | |
| 64 | P43490_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 65 | P43490_POP | POP | n/a | 4995;18628280;57345951; | n/a | PYROPHOSPHATE 2- | n/a | |
| 66 | P43490_PPV | PPV | DB04160 | 1023;21961011; | CHEMBL1160571 | PYROPHOSPHATE | n/a | |
| 67 | P43490_PRP | PRP | DB01632 | 7339 | n/a | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose | n/a | |
| 68 | P43490_QCT | QCT | n/a | 5280459 | CHEMBL82242 | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside | n/a | |
| 69 | P43490_SJ6 | SJ6 | n/a | 17078879 | n/a | N-[[4-(6-methyl-1,3-benzoxazol-2-yl)phenyl]methyl]pyridine-3-carboxamide | n/a | |
| 70 | P43490_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 71 | P43490_TIE | TIE | n/a | 92895287 | CHEMBL5433493 | (3R)-1-[2-(4-methylphenyl)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]-N-{[4-(methylsulfanyl)phenyl]methyl}piperidine-3-carboxamide | n/a | |
| 72 | P43490_TIW | TIW | n/a | 92895288 | CHEMBL5426484 | (3S)-1-[2-(4-methylphenyl)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]-N-{[4-(methylsulfanyl)phenyl]methyl}piperidine-3-carboxamide | n/a | |
| 73 | P43490_TK0 | TK0 | n/a | 168433039 | n/a | (3S)-N-[(1-benzothiophen-5-yl)methyl]-1-[6-(4-{2-[(2E)-3-(pyridin-3-yl)prop-2-enamido]ethyl}phenyl)thieno[2,3-d]pyrimidin-4-yl]piperidine-3-carboxamide | n/a | |
| 74 | P43490_TKF | TKF | n/a | 165406683 | CHEMBL5396153 | (3S)-N-[(1-benzothiophen-5-yl)methyl]-1-{2-[4-(trifluoromethyl)phenyl]-2H-pyrazolo[3,4-d]pyrimidin-4-yl}piperidine-3-carboxamide | n/a | |
| 75 | P43490_UNU | UNU | n/a |