Gene name: CHRNA4
Protein name: Neuronal acetylcholine receptor
List of molecules and drugs that interact with protein P43681
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P43681_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 2 | P43681_NCT | NCT | DB00184 | 89594 | CHEMBL3 | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE | agonist | Ki(nM) = 1.0 |
| 3 | P43681_QMR | QMR | DB01273 | 5310966 | CHEMBL1076903 | VARENICLINE | partial agonist | Ki(nM) = 0.04 IC50(nM) = 94.0 EC50(nM) = 950.0 |
| 4 | P43681_Y01 | Y01 | n/a | 65082 | n/a | CHOLESTEROL HEMISUCCINATE | n/a | |
| 5 | P43681_DB00241 | n/a | DB00241 | n/a | n/a | Butalbital | antagonist | |
| 6 | P43681_DB00306 | n/a | DB00306 | n/a | n/a | Talbutal | antagonist | |
| 7 | P43681_DB00312 | n/a | DB00312 | n/a | n/a | Pentobarbital | antagonist | |
| 8 | P43681_DB00333 | n/a | DB00333 | n/a | n/a | Methadone | antagonist | |
| 9 | P43681_DB00418 | n/a | DB00418 | n/a | n/a | Secobarbital | antagonist | |
| 10 | P43681_VOK | VOK | DB00463 | 4099 | CHEMBL450 | Metharbital | antagonist | |
| 11 | P43681_DB00514 | n/a | DB00514 | n/a | n/a | Dextromethorphan | antagonist | |
| 12 | P43681_N6W | N6W | DB00564 | 2554 | CHEMBL108 | Carbamazepine | n/a | |
| 13 | P43681_DB00572 | n/a | DB00572 | n/a | n/a | Atropine | n/a | |
| 14 | P43681_DB00599 | n/a | DB00599 | n/a | n/a | Thiopental | antagonist | |
| 15 | P43681_DB00657 | n/a | DB00657 | n/a | n/a | Mecamylamine | n/a | Ki(nM) = 560.0 |
| 16 | P43681_DB00747 | n/a | DB00747 | n/a | n/a | Scopolamine | inhibitor | |
| 17 | P43681_DB00753 | n/a | DB00753 | n/a | n/a | Isoflurane | antagonist | |
| 18 | P43681_EST | EST | DB00783 | 5757 | CHEMBL135 | Estradiol | binder | |
| 19 | P43681_DB00794 | n/a | DB00794 | n/a | n/a | Primidone | antagonist | |
| 20 | P43681_DB00849 | n/a | DB00849 | n/a | n/a | Methylphenobarbital | antagonist | |
| 21 | P43681_EOH | EOH | DB00898 | 702 | CHEMBL545 | Ethanol | n/a | |
| 22 | P43681_DB00915 | n/a | DB00915 | n/a | n/a | Amantadine | antagonist | |
| 23 | P43681_DB00981 | n/a | DB00981 | n/a | n/a | Physostigmine | n/a | |
| 24 | P43681_UQA | UQA | DB01174 | 4763 | CHEMBL40 | Phenobarbital | antagonist | |
| 25 | P43681_DME | DME | DB01245 | 2968 | CHEMBL1190 | Decamethonium | n/a | Ki(nM) = 460.0 |
| 26 | P43681_DB01351 | n/a | DB01351 | n/a | n/a | Amobarbital | antagonist | |
| 27 | P43681_DB01352 | n/a | DB01352 | n/a | n/a | Aprobarbital | antagonist | |
| 28 | P43681_DB01353 | n/a | DB01353 | n/a | n/a | Butobarbital | antagonist | |
| 29 | P43681_DB01354 | n/a | DB01354 | n/a | n/a | Heptabarbital | antagonist | |
| 30 | P43681_DB01355 | n/a | DB01355 | n/a | n/a | Hexobarbital | antagonist | |
| 31 | P43681_DB01483 | n/a | DB01483 | n/a | n/a | Barbital | antagonist | |
| 32 | P43681_DB01496 | n/a | DB01496 | n/a | n/a | Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione | antagonist | |
| 33 | P43681_DB05458 | n/a | DB05458 | n/a | n/a | Pozanicline | modulator | Ki(nM) = 26.0 |
| 34 | P43681_EPJ | EPJ | DB07720 | 854023 | CHEMBL298826 | Epibatidine | agonist | Kd(nM) = 0.03 |
| 35 | P43681_C5E | C5E | DB09028 | 10235 | CHEMBL497939 | Cytisine | agonist | Ki(nM) = 0.23 EC50(nM) = 0.42 |
| 36 | P43681_DB13952 | n/a | DB13952 | n/a | n/a | Estradiol acetate | n/a | |
| 37 | P43681_DB13953 | n/a | DB13953 | n/a | n/a | Estradiol benzoate | n/a | |
| 38 | P43681_DB13954 | n/a | DB13954 | n/a | n/a | Estradiol cypionate | n/a | |
| 39 | P43681_DB13955 | n/a | DB13955 | n/a | n/a | Estradiol dienanthate | n/a | |
| 40 | P43681_DB13956 | n/a | DB13956 | n/a | n/a | Estradiol valerate | n/a |