Gene name: lpxC
Protein name: UDP-3-O-acyl-N-acetylglucosamine deacetylase (UDP-3-O-acyl-GlcNAc
List of molecules and drugs that interact with protein P47205
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P47205_03I | 03I | n/a | 54754548 | CHEMBL1956144 | (2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-{4'-[3-(morpholin-4-yl)propoxy]biphenyl-4-yl}butanamide | n/a | |
| 2 | P47205_1JS | 1JS | n/a | 71297191 | n/a | N~1~-hydroxy-N~5~-(3-hydroxypropyl)-N~2~-[4-(phenylethynyl)benzoyl]-L-glutamamide | n/a | |
| 3 | P47205_1WL | 1WL | n/a | 71660651 | CHEMBL2420197 | Nalpha-{4-[4-(4-aminophenyl)buta-1,3-diyn-1-yl]benzoyl}-N-hydroxy-L-histidinamide | n/a | |
| 4 | P47205_1WM | 1WM | n/a | 71660652 | CHEMBL2420202 | (betaS)-Nalpha-{4-[4-(4-aminophenyl)buta-1,3-diyn-1-yl]benzoyl}-N,beta-dihydroxy-L-tyrosinamide | n/a | |
| 5 | P47205_1WN | 1WN | n/a | 71660653 | CHEMBL2420203 | (betaS)-Nalpha-{4-[4-(4-aminophenyl)buta-1,3-diyn-1-yl]benzoyl}-N,beta-dihydroxy-beta-methyl-L-tyrosinamide | n/a | |
| 6 | P47205_2SZ | 2SZ | n/a | 78333420 | n/a | 6-(1H-benzimidazol-1-yl)-N-hydroxy-5-[4-({6-[(4-methylpiperazin-1-yl)methyl]pyridin-3-yl}ethynyl)phenyl]pyridine-3-carboxamide | n/a | |
| 7 | P47205_3P3 | 3P3 | n/a | 11164341 | CHEMBL1230182 | N-[(1S,2R)-2-hydroxy-1-(hydroxycarbamoyl)propyl]-4-(4-phenylbuta-1,3-diyn-1-yl)benzamide | n/a | |
| 8 | P47205_5EM | 5EM | n/a | 59417262 | n/a | N-[(2S)-3-amino-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-4-[4-(4-aminophenyl)buta-1,3-diyn-1-yl]benzamide | n/a | |
| 9 | P47205_5EN | 5EN | n/a | 89787752 | n/a | 4-[4-(4-aminophenyl)buta-1,3-diyn-1-yl]-N-[(2S,3S)-4,4-difluoro-3-hydroxy-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]benzamide | n/a | |
| 10 | P47205_6G8 | 6G8 | n/a | 164889257 | n/a | (2S,4S)-N-[(3R,5R)-1-cyclopropylcarbonyl-5-[[[2-methyl-4-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]phenyl]carbonylamino]methyl]pyrrolidin-3-yl]-4-fluoranyl-pyrrolidine-2-carboxamide | n/a | |
| 11 | P47205_7PX | 7PX | n/a | 164889260 | n/a | (2~{R},4~{R})-4-[[(2~{S},4~{S})-4-fluoranylpyrrolidin-2-yl]carbonylamino]-1-(2-methylpropanoyl)-~{N}-[[4-(2-phenylethynyl)phenyl]methyl]pyrrolidine-2-carboxamide | n/a | |
| 12 | P47205_7S2 | 7S2 | n/a | 164889261 | n/a | (2R,4R)-N-[[4-(4-cyclopropylbuta-1,3-diynyl)phenyl]methyl]-1-(2-methylpropanoyl)-4-[[(2S,4R)-4-oxidanylpyrrolidin-2-yl]carbonylamino]pyrrolidine-2-carboxamide | n/a | |
| 13 | P47205_7S6 | 7S6 | n/a | 164889262 | n/a | (2R,4R)-4-[[(2S,4S)-4-fluoranylpyrrolidin-2-yl]carbonylamino]-1-(2-methylpropanoyl)-N-[[4-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]phenyl]methyl]pyrrolidine-2-carboxamide | n/a | |
| 14 | P47205_7T5 | 7T5 | n/a | 164889263 | n/a | (2S,4S)-4-fluoranyl-N-[(3R,5R)-5-[[[4-[2-(4-methylphenyl)ethynyl]phenyl]carbonylamino]methyl]-1-(2-methylpropanoyl)pyrrolidin-3-yl]pyrrolidine-2-carboxamide | n/a | |
| 15 | P47205_7TD | 7TD | n/a | 59323957 | CHEMBL4097399 | N-[(2S)-3-amino-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-4-[(but-2-yn-1-yl)oxy]benzamide | n/a | |
| 16 | P47205_7TF | 7TF | n/a | 164889264 | n/a | (2R,4R)-1-cyclopropylcarbonyl-4-[[(2S,4S)-4-fluoranylpyrrolidin-2-yl]carbonylamino]-N-[[4-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]phenyl]methyl]pyrrolidine-2-carboxamide | n/a | |
| 17 | P47205_8GJ | 8GJ | n/a | 56964907 | CHEMBL2023402 | (2R)-4-[4-(2-fluoro-4-methoxyphenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide | n/a | |
| 18 | P47205_8IY | 8IY | n/a | 165430607 | n/a | (2S,4S)-N-((3R,5R)-1-(cyclopropanecarbonyl)-5-((4-((4-((S)-2-hydroxy-1-methoxyethyl)phenyl)ethynyl)benzamido)methyl)pyrrolidin-3-yl)-4-fluoropyrrolidine-2-carboxamide | n/a | |
| 19 | P47205_8Q8 | 8Q8 | n/a | 124222738 | n/a | (2~{S})-3-azanyl-2-[[(1~{R})-5-[2-[4-[[2-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]ethynyl]-2,3-dihydro-1~{H}-inden-1-yl]amino]-3-methyl-~{N}-oxidanyl-butanamide | n/a | |
| 20 | P47205_98O | 98O | n/a | 165416265 | n/a | (2S,4S)-N-((3R,5R)-5-((2-chloro-4-((4-(morpholinomethyl)phenyl)ethynyl)benzamido)methyl)-1-(cyclopropanecarbonyl)pyrrolidin-3-yl)-4-fluoropyrrolidine-2-carboxamide | n/a | |
| 21 | P47205_99I | 99I | n/a | 165416266 | n/a | (2S,4S)-N-((3R,5R)-1-(cyclopropanecarbonyl)-5-((3-fluoro-4-((4-(morpholinomethyl)phenyl)ethynyl)benzamido)methyl)pyrrolidin-3-yl)-4-fluoropyrrolidine-2-carboxamide | n/a | |
| 22 | P47205_9A1 | 9A1 | n/a | 165416268 | n/a | (4S)-N-((3R,5R)-1-(cyclopropanecarbonyl)-5-((5-(phenylethynyl)thiophene-2-carboxamido)methyl)pyrrolidin-3-yl)-4-fluoropyrrolidine-2-carboxamide | n/a | |
| 23 | P47205_9B9 | 9B9 | n/a | 165416269 | n/a | (2S,4S)-N-((3R,5R)-1-(cyclopropanecarbonyl)-5-((4-(((1R,2R)-2-(methoxymethyl)cyclopropyl)buta-1,3-diyn-1-yl)benzamido)methyl)pyrrolidin-3-yl)-4-fluoropyrrolidine-2-carboxamide | n/a | |
| 24 | P47205_9DO | 9DO | n/a | 165416267 | n/a | (2S,4S)-N-[(3R,5R)-1-cyclopropylcarbonyl-5-[[[4-[2-[4-[(1S)-2-methoxy-1-oxidanyl-ethyl]phenyl]ethynyl]phenyl]carbonylamino]methyl]pyrrolidin-3-yl]-4-fluoranyl-pyrrolidine-2-carboxamide | n/a | |
| 25 | P47205_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 26 | P47205_C90 | C90 | DB07536 | 11546620 | CHEMBL260091 | N-{(1S,2R)-2-hydroxy-1-[(hydroxyamino)carbonyl]propyl}-4-{[4-(morpholin-4-ylmethyl)phenyl]ethynyl}benzamide | n/a | |
| 27 | P47205_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 28 | P47205_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 29 | P47205_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 30 | P47205_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 31 | P47205_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 32 | P47205_FXU | FXU | n/a | 155289362 | CHEMBL4744809 | (2R)-2-azanyl-4-methylsulfonyl-N-[3-(trifluoromethyloxy)phenyl]butanamide | n/a | |
| 33 | P47205_FXX | FXX | n/a | 155289363 | CHEMBL4755686 | (3R)-3-azanyl-4-oxidanylidene-4-[[3-(trifluoromethyloxy)phenyl]amino]butanoic acid | n/a | |
| 34 | P47205_FY6 | FY6 | n/a | 155289364 | n/a | (1S)-1-[1-[3-(4-chlorophenyl)propyl]imidazol-2-yl]ethanol | n/a | |
| 35 | P47205_FY9 | FY9 | n/a | 155289365 | CHEMBL4756867 | (2R,3R)-2-azanyl-1-[4-[[4-[2-[4-(hydroxymethyl)phenyl]ethynyl]phenyl]methyl]piperidin-1-yl]-4-methylsulfonyl-3-oxidanyl-butan-1-one | n/a | |
| 36 | P47205_FYF | FYF | n/a | 155289366 | n/a | (1S)-1-[1-[(5-phenyl-1,2-oxazol-3-yl)methyl]imidazol-2-yl]ethanol | n/a | |
| 37 | P47205_FYL | FYL | n/a | 150045929 | CHEMBL4747965 | 2-azanyl-2-[[4-[2-[3-[[2-[(1S)-1-oxidanylethyl]imidazol-1-yl]methyl]-1,2-oxazol-5-yl]ethynyl]phenoxy]methyl]propane-1,3-diol | n/a | |
| 38 | P47205_FYR | FYR | n/a | 12270704 | CHEMBL475848 | 2-oxidanyl-4-phenyl-benzoic acid | n/a | |
| 39 | P47205_FZ0 | FZ0 | n/a | 24692644 | CHEMBL4758755 | 2-azanyl-N-[3-(trifluoromethyloxy)phenyl]ethanamide | n/a | |
| 40 | P47205_FZ3 | FZ3 | n/a | 9991046 | CHEMBL213493 | 1-[3-(4-chlorophenyl)propyl]imidazole | n/a | |
| 41 | P47205_FZ6 | FZ6 | n/a | 142480001 | CHEMBL4747065 | (2R)-2-azanyl-3-oxidanyl-N-[3-(trifluoromethyloxy)phenyl]propanamide | n/a | |
| 42 | P47205_GAI | GAI | DB00536 | 3520 | CHEMBL821 | GUANIDINE | n/a | |
| 43 | P47205_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 44 | P47205_GVR | GVR | DB07861 | 9823454 | CHEMBL261713 | (2R)-N-hydroxy-3-naphthalen-2-yl-2-[(naphthalen-2-ylsulfonyl)amino]propanamide | n/a | |
| 45 | P47205_H4L | H4L | n/a | 155294516 | CHEMBL4752810 | 3-[4-[2-[3-[[2-[(1~{S})-1-oxidanylethyl]imidazol-1-yl]methyl]-1,2-oxazol-5-yl]ethynyl]phenyl]propan-1-ol | n/a | |
| 46 | P47205_H4O | H4O | n/a | 153592905 | CHEMBL4784327 | 5-[4-[3-[[2-[(1~{S})-1-oxidanylethyl]imidazol-1-yl]methyl]-1,2-oxazol-5-yl]phenyl]pent-4-yn-1-ol | n/a | |
| 47 | P47205_H4R | H4R | n/a | n/a | CHEMBL4798122 | 4-[(1~{R},5~{S})-6-[2-[4-[3-[[2-[(1~{S})-1-oxidanylethyl]imidazol-1-yl]methyl]-1,2-oxazol-5-yl]phenyl]ethynyl]-3-azabicyclo[3.1.0]hexan-3-yl]butanoic acid | n/a | |
| 48 | P47205_HUM | HUM | n/a | 138454242 | n/a | (2S)-4-{4-[4-(benzyloxy)-2-fluorophenyl]-2-oxopyridin-1(2H)-yl}-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide | n/a | |
| 49 | P47205_JBA | JBA | n/a | 118051063 | CHEMBL4437188 | (2R)-3-{(5S)-3-[4-(cyclopropylethynyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}-N-hydroxy-2-methyl-2-(methylsulfonyl)propanamide | n/a | |
| 50 | P47205_JCG | JCG | n/a | 138454243 | n/a | (2R)-4-{4-[4-(benzyloxy)-2-fluorophenyl]-2-oxopyridin-1(2H)-yl}-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide | n/a | |
| 51 | P47205_JWM | JWM | n/a | 118659530 | n/a | N-[(2R)-1-(hydroxyamino)-3-methyl-3-(methylsulfonyl)-1-oxobutan-2-yl]-4-(6-hydroxyhexa-1,3-diyn-1-yl)benzamide | n/a | |
| 52 | P47205_JWP | JWP | n/a | n/a | n/a | N-[(2S)-1-(hydroxyamino)-3-methyl-3-{[(oxetan-3-yl)methyl]sulfonyl}-1-oxobutan-2-yl]-4-(6-hydroxyhexa-1,3-diyn-1-yl)benzamide | n/a | |
| 53 | P47205_L52 | L52 | n/a | 59697354 | n/a | N-[(2S)-3-amino-1-(hydroxyamino)-1-oxopropan-2-yl]-4-(4-phenylbuta-1,3-diyn-1-yl)benzamide | n/a | |
| 54 | P47205_L58 | L58 | n/a | 59697583 | n/a | 4'-bromo-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]biphenyl-4-carboxamide | n/a | |
| 55 | P47205_L59 | L59 | n/a | 59697614 | n/a | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(phenylethynyl)benzamide | n/a | |
| 56 | P47205_L63 | L63 | n/a | 59697533 | n/a | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]biphenyl-4-carboxamide | n/a | |
| 57 | P47205_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 58 | P47205_MPB | MPB | DB14212 | 7456 | CHEMBL325372 | 4-HYDROXY-BENZOIC ACID METHYL ESTER | n/a | |
| 59 | P47205_MPO | MPO | DB03434 | 70807;2723950; | CHEMBL1234443 | 3[N-MORPHOLINO]PROPANE SULFONIC ACID | n/a | |
| 60 | P47205_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 61 | P47205_NO3 | NO3 | DB14049 | 943 | CHEMBL186200 | NITRATE ION | n/a | |
| 62 | P47205_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 63 | P47205_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 64 | P47205_RFN | RFN | n/a | 56593152 | CHEMBL2023131 | (2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-(2-oxo-4-phenylpyridin-1(2H)-yl)butanamide | n/a | |
| 65 | P47205_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 66 | P47205_W4M | W4M | n/a | 155804580 | n/a | (hydroxy{(1S)-1-(methylsulfanyl)-2-[5-({4-[(morpholin-4-yl)methyl]phenyl}ethynyl)-1H-benzotriazol-1-yl]ethyl}amino)methanol | n/a | |
| 67 | P47205_W4P | W4P | n/a | 155289166 | n/a | N-hydroxy-N-[(1S)-2-{5-[(4-{[2-(hydroxymethyl)-1H-imidazol-1-yl]methyl}phenyl)ethynyl]-1H-benzotriazol-1-yl}-1-(methylsulfanyl)ethyl]formamide | n/a | |
| 68 | P47205_W8P | W8P | n/a | 155289167 | n/a | N-hydroxy-N-[(1R)-2-{5-[(4-{[2-(hydroxymethyl)-1H-imidazol-1-yl]methyl}phenyl)ethynyl]-1H-benzotriazol-1-yl}-1-(methylsulfanyl)ethyl]formamide | n/a | |
| 69 | P47205_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a |