Gene name: PREP
Protein name: Prolyl endopeptidase (PE)
List of molecules and drugs that interact with protein P48147
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P48147_552 | 552 | DB07148 | 46937054 | n/a | (6S)-1-chloro-3-[(4-fluorobenzyl)oxy]-6-(pyrrolidin-1-ylcarbonyl)pyrrolo[1,2-a]pyrazin-4(6H)-one | n/a | |
| 2 | P48147_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 3 | P48147_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 4 | P48147_SGL | SGL | DB01684 | 5289354 | n/a | 1-Hydroxy-1-Thio-Glycerol | inhibitor | |
| 5 | P48147_CSX | CSX | DB03382 | 49866839 | n/a | S-oxy-L-cysteine | n/a | |
| 6 | P48147_ZPR | ZPR | DB03535 | 122623 | CHEMBL79993 | Z-Pro-Prolinal | inhibitor | Ki(nM) = 0.4 IC50(nM) = 1.1 |
| 7 | P48147_SGM | SGM | DB03864 | 447638 | n/a | Monothioglycerol | n/a | |
| 8 | P48147_X98 | X98 | DB08738 | 25155578 | CHEMBL459149 | 1-{3-oxo-3-[(2S)-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]propyl}-3-phenylquinoxalin-2(1H)-one | n/a | |
| 9 | P48147_X99 | X99 | DB08739 | 25102845 | CHEMBL458975 | 2-{3-[(2S)-4,4-difluoro-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]-3-oxopropyl}-isoindole-1,3(2H)-dione | n/a |