Gene name: MTNR1B
Protein name: Melatonin receptor type
List of molecules and drugs that interact with protein P49286
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P49286_JEV | JEV | DB00980 | 208902 | CHEMBL1218 | N-{2-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl}propanamide | multitarget | Ki(nM) = 0.045 |
| 2 | P49286_ML1 | ML1 | DB01065 | 896 | CHEMBL45 | Melatonin | agonist | Ki(nM) = 0.12 IC50(nM) = 0.3 EC50(nM) = 0.069 |
| 3 | P49286_STL | STL | DB02709 | 445154 | CHEMBL165 | Resveratrol | n/a | |
| 4 | P49286_AWY | AWY | DB06594 | 82148 | CHEMBL10878 | Agomelatine | agonist | Ki(nM) = 0.03 IC50(nM) = 0.99 EC50(nM) = 0.1 |
| 5 | P49286_DB09071 | n/a | DB09071 | n/a | n/a | Tasimelteon | agonist | |
| 6 | P49286_3E8 | 3E8 | DB15133 | 25171648 | CHEMBL3402762 | Tepotinib | inhibitor |