Gene name: FASN
Protein name: Fatty acid synthase
List of molecules and drugs that interact with protein P49327
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P49327_2W4 | 2W4 | n/a | 67376285 | CHEMBL3646801 | 4-[4-(1-benzofuran-5-yl)phenyl]-5-{[(3S)-1-(cyclopropylcarbonyl)pyrrolidin-3-yl]methyl}-2,4-dihydro-3H-1,2,4-triazol-3-one | n/a | |
| 2 | P49327_4XN | 4XN | n/a | 117999157 | CHEMBL4128261 | 6-{[(3R)-1-(cyclopropylcarbonyl)pyrrolidin-3-yl]methyl}-5-[4-(1-methyl-1H-indazol-5-yl)phenyl]-4,6-diazaspiro[2.4]hept-4-en-7-one | n/a | |
| 3 | P49327_7FA | 7FA | n/a | n/a | n/a | methyl (R)-(6Z,9Z,12Z)-octadeca-6,9,12-trien-1-ylphosphonofluoridate | n/a | |
| 4 | P49327_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 5 | P49327_CAC | CAC | n/a | 167250 | n/a | CACODYLATE ION | n/a | |
| 6 | P49327_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 7 | P49327_COA | COA | DB01992 | 87642 | CHEMBL1213327 | COENZYME A | n/a | |
| 8 | P49327_DH9 | DH9 | n/a | 14607536 | n/a | (2S,3S,5S)-5-[(N-FORMYL-L-LEUCYL)OXY]-2-HEXYL-3-HYDROXYHEXADECANOIC ACID | n/a | |
| 9 | P49327_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 10 | P49327_DTT | DTT | DB04447 | 439196 | CHEMBL406270 | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | n/a | |
| 11 | P49327_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 12 | P49327_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 13 | P49327_IMD | IMD | DB03366 | 444234;4434133;21983501; | n/a | IMIDAZOLE | n/a | |
| 14 | P49327_K | K | n/a | 813 | CHEMBL1233793 | POTASSIUM ION | n/a | |
| 15 | P49327_KUA | KUA | n/a | 117631954 | CHEMBL4449818 | {4-[4-(1,3-benzoxazol-2-yl)benzene-1-carbonyl]piperazin-1-yl}(1-hydroxycyclopropyl)methanone | n/a | |
| 16 | P49327_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 17 | P49327_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 18 | P49327_NDP | NDP | DB02338 | 5884;134821689; | CHEMBL407009 | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | n/a | |
| 19 | P49327_NI | NI | n/a | 934 | n/a | NICKEL (II) ION | n/a | |
| 20 | P49327_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 21 | P49327_SCN | SCN | n/a | 9322 | n/a | THIOCYANATE ION | n/a | |
| 22 | P49327_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 23 | P49327_TCL | TCL | DB08604 | 5564 | CHEMBL849 | TRICLOSAN | n/a | |
| 24 | P49327_X5O | X5O | DB17576 | 66548316 | CHEMBL3661754 | denifanstat | n/a | |
| 25 | P49327_ZEG | ZEG | n/a | 9356437 | n/a | 4-{4-[2-(4-fluorophenyl)-1,3-thiazol-4-yl]benzene-1-sulfonyl}morpholine | n/a | |
| 26 | P49327_ZEP | ZEP | n/a | 118362921 | n/a | N,N-diethyl-4-{2-[(2-fluorophenyl)methyl]-1,3-thiazol-4-yl}benzene-1-sulfonamide | n/a | |
| 27 | P49327_1X9 | 1X9 | DB01034 | 5282054 | CHEMBL45627 | Cerulenin | inhibitor | |
| 28 | P49327_DB01083 | n/a | DB01083 | n/a | n/a | Orlistat | inhibitor | Ki(nM) = 280.0 IC50(nM) = 1350.0 |