Gene name: PSEN1
Protein name: Presenilin-1 (PS-1) (EC
List of molecules and drugs that interact with protein P49768
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P49768_EN9 | EN9 | DB11893 | 46883536 | CHEMBL1090771 | (2R)-2-[(4-chlorophenyl)sulfonyl-[[2-fluoranyl-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-tris(fluoranyl)pentanamide | modulator | |
| 2 | P49768_ESF | ESF | DB12463 | 9843750 | CHEMBL520733 | (2S)-2-hydroxy-3-methyl-N-[(2S)-1-[[(5S)-3-methyl-4-oxo-2,5-dihydro-1H-3-benzazepin-5-yl]amino]-1-oxopropan-2-yl]butanamide | modulator | |
| 3 | P49768_FTO | FTO | n/a | 5479543 | CHEMBL302004 | ~{tert}-butyl ~{N}-[(2~{S},3~{R},5~{R})-6-[[(2~{S})-1-[[(2~{S})-1-azanyl-1-oxidanylidene-3-phenyl-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]amino]-3-oxidanyl-6-oxidanylidene-1-phenyl-5-(phenylmethyl)hexan-2-yl]carbamate | n/a | |
| 4 | P49768_GZR | GZR | DB05171 | 11560787 | CHEMBL1224151 | 1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]piperidin-2-one | modulator | |
| 5 | P49768_IGD | IGD | n/a | n/a | CHEMBL372199 | ~{N}-[4-[2,5-bis(fluoranyl)phenyl]-4-(4-chlorophenyl)sulfonyl-cyclohexyl]-1,1,1-tris(fluoranyl)methanesulfonamide | n/a | |
| 6 | P49768_PC1 | PC1 | n/a | 94190 | n/a | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | n/a | |
| 7 | P49768_PTY | PTY | n/a | 446872 | n/a | PHOSPHATIDYLETHANOLAMINE | n/a |