Gene name: KIF11
Protein name: Kinesin-like protein KIF11
List of molecules and drugs that interact with protein P52732
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P52732_2AZ | 2AZ | n/a | 11840905 | n/a | N-(3-AMINOPROPYL)-N-[(R)-(3-BENZYL-5-CHLORO-4-OXO-3,4-DIHYDROPYRROLO[2,1-F][1,2,4]TRIAZIN-2-YL)(CYCLOPROPYL)METHYL]-4-METHYLBENZAMIDE | n/a | |
| 2 | P52732_2XA | 2XA | n/a | 21140145;72199506; | CHEMBL409102 | (2R)-2-AMINO-3-[(4-CHLOROPHENYL)-DIPHENYL-METHYL]SULFANYL-PROPANOIC ACID | n/a | |
| 3 | P52732_3QC | 3QC | DB07064 | 6857690 | CHEMBL205786 | (4R)-4-(3-HYDROXYPHENYL)-N,N,7,8-TETRAMETHYL-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE | n/a | IC50(nM) = 104.0 |
| 4 | P52732_4A2 | 4A2 | n/a | 25165666 | CHEMBL558476 | (2E)-2-(3-fluoranyl-4-methoxy-phenyl)imino-1-[[2-(trifluoromethyl)phenyl]methyl]-3H-benzimidazole-5-carboxylic acid | n/a | |
| 5 | P52732_4C5 | 4C5 | n/a | 7472793;7472794; | CHEMBL392369 | (2R)-2-azanyl-3-[(4-methoxyphenyl)-diphenyl-methyl]sulfanyl-propanoic acid | n/a | |
| 6 | P52732_5C5 | 5C5 | n/a | 71748289 | CHEMBL3633366 | (2R)-2-azanyl-3-[[2-(4-methoxyphenyl)-2-tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaenyl]sulfanyl]propanoic acid | n/a | |
| 7 | P52732_6LX | 6LX | DB05546 | 9936388 | CHEMBL2325429 | N-(3-aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxo-4H-chromen-2-yl)-2-methylpropyl]-4-methylbenzamide | n/a | |
| 8 | P52732_ADP | ADP | DB16833 | 6022 | CHEMBL14830 | ADENOSINE-5'-DIPHOSPHATE | n/a | |
| 9 | P52732_AF3 | AF3 | n/a | 2124;10129892; | n/a | ALUMINUM FLUORIDE | n/a | |
| 10 | P52732_ANP | ANP | n/a | 33113 | CHEMBL1230989 | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | n/a | |
| 11 | P52732_B4S | B4S | n/a | 44590437 | CHEMBL450994 | 3'-fluoro-4'-(trifluoromethyl)biphenyl-4-sulfonamide | n/a | |
| 12 | P52732_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 13 | P52732_CD | CD | n/a | 31193 | n/a | CADMIUM ION | n/a | |
| 14 | P52732_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 15 | P52732_CO | CO | n/a | 104729 | n/a | COBALT (II) ION | n/a | |
| 16 | P52732_DQ6 | DQ6 | n/a | 57325589;72200770; | CHEMBL2022995 | (2S)-2-AMINO-5-(3-METHYLPHENYL)-5,5-DIPHENYLPROPANOIC ACID | n/a | |
| 17 | P52732_DQ7 | DQ7 | n/a | 56964577 | CHEMBL2022996 | (2R)-2-AMINO-5-(3-METHYLPHENYL)-5,5-DIPHENYLPROPANOIC ACID | n/a | |
| 18 | P52732_DQ8 | DQ8 | n/a | 57326580 | CHEMBL2022990 | 1-(3-{[(2-aminoethyl)sulfanyl](diphenyl)methyl}phenyl)ethanone | n/a | |
| 19 | P52732_EGB | EGB | n/a | 49863704 | CHEMBL1213955 | (4S)-4-(3-HYDROXYPHENYL)-7,7-DIMETHYL-2-THIOXO-2,3,4,6,7,8-HEXAHYDROQUINAZOLIN-5(1H)-ONE | n/a | |
| 20 | P52732_EMQ | EMQ | n/a | 23634407 | CHEMBL1077204 | 1-[2-(dimethylamino)ethyl]-3-{[(2R,4aS,5R,10bS)-5-phenyl-9-(trifluoromethyl)-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-yl]methyl}urea | n/a | |
| 21 | P52732_EOK | EOK | n/a | 686905 | CHEMBL4283764 | (~{N}~{Z})-~{N}-[(5~{S})-4-ethanoyl-5-methyl-5-phenyl-1,3,4-thiadiazolidin-2-ylidene]ethanamide | n/a | |
| 22 | P52732_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 23 | P52732_G7X | G7X | DB06188 | 6851740 | CHEMBL228814 | ISPINESIB MESILATE | inhibitor | |
| 24 | P52732_GCE | GCE | DB06040 | 44224257 | CHEMBL2347655 | (2~{S})-2-(3-azanylpropyl)-5-[2,5-bis(fluoranyl)phenyl]-~{N}-methoxy-~{N}-methyl-2-phenyl-1,3,4-thiadiazole-3-carboxamide | inhibitor | |
| 25 | P52732_K | K | n/a | 813 | CHEMBL1233793 | POTASSIUM ION | n/a | |
| 26 | P52732_K01 | K01 | DB08032 | 1190625 | CHEMBL228369 | N,N-DIETHYL-2-[(2-THIENYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE | n/a | IC50(nM) = 1700.0 |
| 27 | P52732_K02 | K02 | DB08033 | 16122638 | n/a | (5R)-N,N-DIETHYL-5-METHYL-2-[(THIOPHEN-2-YLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE | n/a | |
| 28 | P52732_K03 | K03 | n/a | 16122639 | CHEMBL390721 | N,N-DIETHYL-5,5-DIMETHYL-2-[(2-THIENYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE | n/a | |
| 29 | P52732_K30 | K30 | DB08037 | 11655511 | CHEMBL481931 | (2S)-4-(2,5-difluorophenyl)-N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide | inhibitor | |
| 30 | P52732_K5E | K5E | n/a | 44237114 | n/a | (4S,5R)-5-hydroxy-4-(3-hydroxyphenyl)-3,4,5,6,7,8-hexahydroquinazoline-2(1H)-thione | n/a | |
| 31 | P52732_KEN | KEN | n/a | 1146 | CHEMBL439723 | N,N-dimethylmethanamine | n/a | |
| 32 | P52732_KZ9 | KZ9 | n/a | 757000 | CHEMBL1213954 | (S)-4-(3-HYDROXYPHENYL)-2-THIOXO-1,2,3,4,7,8-HEXAHYDROQUINAZOLIN-5(6H)-ONE | n/a | |
| 33 | P52732_L31 | L31 | n/a | 49867220 | n/a | 3-[(1R)-2-acetyl-6-methyl-2,3,4,9-tetrahydro-1H-beta-carbolin-1-yl]phenol | n/a | |
| 34 | P52732_L47 | L47 | DB03996 | 5288685 | n/a | 3-[(5S)-1-ACETYL-3-(2-CHLOROPHENYL)-4,5-DIHYDRO-1H-PYRAZOL-5-YL]PHENOL | n/a | |
| 35 | P52732_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 36 | P52732_MKK | MKK | n/a | 11539950 | n/a | 1-[(4R)-4-[3-(4-ACETYLPIPERAZIN-1-YL)PROPYL]-1-(2-FLUORO-5-METHYLPHENYL)-4-PHENYL-4,5-DIHYDRO-1H-PYRAZOL-3-YL]ETHANONE | n/a | |
| 37 | P52732_MKR | MKR | n/a | 11662966 | CHEMBL250125 | 1-{(3R,3AR)-3-[3-(4-ACETYLPIPERAZIN-1-YL)PROPYL]-8-FLUORO-3-PHENYL-3A,4-DIHYDRO-3H-PYRAZOLO[5,1-C][1,4]BENZOXAZIN-2-YL}ETHANONE | n/a | |
| 38 | P52732_MOY | MOY | DB08198 | 15942673 | CHEMBL522806 | [(4R)-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL](PHENYL)METHANONE | n/a | IC50(nM) = 110.0 |
| 39 | P52732_MZK | MZK | n/a | 12000936 | CHEMBL1222153 | 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one | n/a | |
| 40 | P52732_N2T | N2T | DB08239 | 11675645 | CHEMBL205437 | (2S)-4-(2,5-DIFLUOROPHENYL)-N-METHYL-2-PHENYL-N-PIPERIDIN-4-YL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE | n/a | |
| 41 | P52732_N4T | N4T | DB08244 | 6102824 | CHEMBL204459 | (1S)-1-CYCLOPROPYL-2-[(2S)-4-(2,5-DIFLUOROPHENYL)-2-PHENYL-2,5-DIHYDRO-1H-PYRROL-1-YL]-2-OXOETHANAMINE | n/a | IC50(nM) = 2.0 |
| 42 | P52732_N5T | N5T | DB08246 | 11840968 | CHEMBL380955 | (2S)-4-(2,5-DIFLUOROPHENYL)-N,N-DIMETHYL-2-PHENYL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE | n/a | |
| 43 | P52732_N9H | N9H | DB08250 | 23586165 | n/a | (5S)-5-(3-AMINOPROPYL)-3-(2,5-DIFLUOROPHENYL)-N-ETHYL-5-PHENYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDE | n/a | |
| 44 | P52732_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 45 | P52732_NAT | NAT | DB04331 | 447982;794323; | CHEMBL254432 | ETHYL 4-(3-HYDROXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE | n/a | |
| 46 | P52732_NO3 | NO3 | DB14049 | 943 | CHEMBL186200 | NITRATE ION | n/a | |
| 47 | P52732_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 48 | P52732_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 49 | P52732_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 50 | P52732_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 51 | P52732_V02 | V02 | n/a | 71307932 | n/a | 3-[(R)-2-azanylethylsulfanyl-(3-ethylphenyl)-phenyl-methyl]phenol | n/a | |
| 52 | P52732_X2O | X2O | n/a | 49843457;72199483; | n/a | (2R)-2-AMINO-3-[(2R)-2-METHYL-1,1-DIPHENYL-BUTYL]SULFANYL-PROPANOIC ACID | n/a | |
| 53 | P52732_X7E | X7E | n/a | 46238523 | n/a | (4R)-5-[(S)-(3,4-DIFLUOROPHENYL)(HYDROXY)METHYL]-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-3,4-DIHYDROPYRIMIDINE-2(1H)-THIONE | n/a | |
| 54 | P52732_ZZD | ZZD | n/a | 76044;7058066; | CHEMBL392695 | S-TRITYL-L-CYSTEINE | n/a |