Gene name: METAP1
Protein name: Methionine aminopeptidase 1
List of molecules and drugs that interact with protein P53582
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P53582_1AY | 1AY | n/a | 71602590 | CHEMBL2392921 | (1R)-N~2~-[5-chloro-2-(5-chloropyridin-2-yl)-6-methylpyrimidin-4-yl]-1-phenyl-N~1~-(4-phenylbutyl)ethane-1,2-diamine | n/a | |
| 2 | P53582_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 3 | P53582_ACY | ACY | DB03166 | 176;21980959;160748163; | CHEMBL539 | ACETIC ACID | n/a | |
| 4 | P53582_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 5 | P53582_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 6 | P53582_CO | CO | n/a | 104729 | n/a | COBALT (II) ION | n/a | |
| 7 | P53582_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 8 | P53582_EYF | EYF | n/a | 155804416 | n/a | 1-[(3-methoxyphenyl)methyl]-~{N}-oxidanyl-pyrrolo[2,3-b]pyridine-5-carboxamide | n/a | |
| 9 | P53582_EYL | EYL | n/a | 155804417 | n/a | ~{N}-oxidanyl-1-(phenylmethyl)pyrrolo[2,3-b]pyridine-4-carboxamide | n/a | |
| 10 | P53582_FZ1 | FZ1 | n/a | 58279815 | CHEMBL4079583 | 4-[4-(4-methoxyphenyl)piperazin-1-yl]-2-(pyridin-2-yl)quinazoline | n/a | |
| 11 | P53582_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 12 | P53582_HM2 | HM2 | DB07901 | 2740174 | CHEMBL472879 | 5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE | n/a | IC50(nM) = 700.0 EC50(nM) = 190.0 |
| 13 | P53582_HM4 | HM4 | DB07902 | 11809364 | CHEMBL327579 | TERT-BUTYL {2-[(1,3-THIAZOL-2-YLAMINO)CARBONYL]PYRIDIN-3-YL}CARBAMATE | n/a | IC50(nM) = 400.0 EC50(nM) = 350.0 |
| 14 | P53582_HM5 | HM5 | DB07903 | 11120251 | CHEMBL316308 | 3-[(2,2-DIMETHYLPROPANOYL)AMINO]-N-1,3-THIAZOL-2-YLPYRIDINE-2-CARBOXAMIDE | n/a | IC50(nM) = 2900.0 |
| 15 | P53582_K | K | n/a | 813 | CHEMBL1233793 | POTASSIUM ION | n/a | |
| 16 | P53582_MET | MET | DB00134 | 6137;6992087; | CHEMBL42336 | METHIONINE | n/a | |
| 17 | P53582_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 18 | P53582_MN | MN | n/a | 27854 | n/a | MANGANESE (II) ION | n/a | |
| 19 | P53582_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 20 | P53582_OVA | OVA | DB04324 | 5289086 | n/a | 3,4-DIHYDROXY-2-METHOXY-4-METHYL-3-[2-METHYL-3-(3-METHYL-BUT-2-ENYL) -OXIRANYL]-CYCLOHEXANONE | n/a | |
| 21 | P53582_PVP | PVP | n/a | 2795593 | CHEMBL460432 | 2-{4-[5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl]piperazin-1-yl}ethanol | n/a | |
| 22 | P53582_Q02 | Q02 | n/a | 1550365 | n/a | [(R)-amino(phenyl)methyl]phosphonic acid | n/a | |
| 23 | P53582_Q03 | Q03 | n/a | 15234907 | CHEMBL1673067 | [(R)-amino(cyclohexyl)methyl]phosphonic acid | n/a | |
| 24 | P53582_Q04 | Q04 | n/a | 91664010 | n/a | [(1R)-1-amino-2-cyclohexylethyl]phosphonic acid | n/a | |
| 25 | P53582_Q06 | Q06 | n/a | 91664009 | n/a | [(1R)-1-amino-3-cyclopentylpropyl]phosphonic acid | n/a | |
| 26 | P53582_Q07 | Q07 | n/a | 12084743 | n/a | [(1R,2S)-1-amino-2-methylpentyl]phosphonic acid | n/a | |
| 27 | P53582_Q08 | Q08 | n/a | 91664008 | n/a | [(1R)-1-amino-2-propylpentyl]phosphonic acid | n/a | |
| 28 | P53582_SHX | SHX | n/a | 72193908 | n/a | Nalpha-[5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl]-D-phenylalaninamide | n/a | |
| 29 | P53582_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 30 | P53582_TFD | TFD | n/a | 2725962 | CHEMBL2392771 | N-[5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl]-N'-[6-(trifluoromethyl)pyridin-2-yl]ethane-1,2-diamine | n/a | |
| 31 | P53582_TFV | TFV | n/a | 2725966 | CHEMBL2375628 | N-[5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl]-N'-[5-(trifluoromethyl)pyridin-2-yl]ethane-1,2-diamine | n/a | |
| 32 | P53582_TN4 | TN4 | DB08633 | 5326425 | n/a | (1R,2S,3S,4R)-4-hydroxy-2-methoxy-4-methyl-3-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]cyclohexyl (chloroacetyl)carbamate | n/a | |
| 33 | P53582_Y08 | Y08 | n/a | 51035428 | n/a | (E,2R,3R,4S,5R)-N-[[(3S)-1-cyclopropylcarbonylpiperidin-3-yl]methyl]-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide | n/a | |
| 34 | P53582_Y10 | Y10 | n/a | 51035429 | CHEMBL1738933 | (E,2R,3R,4S,5R)-N-(2,3-dihydro-1H-inden-2-yl)-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide | n/a | |
| 35 | P53582_Y16 | Y16 | n/a | 51035427 | CHEMBL1738934 | (E,2R,3R,4S,5R)-N-(2-azanyl-2-oxidanylidene-ethyl)-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide | n/a | |
| 36 | P53582_YZ6 | YZ6 | n/a | 60167577 | n/a | (E,2R,3R,4S,5R)-N-[(3R)-3-(furan-2-yl)-3-phenyl-propyl]-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide | n/a |