Gene name: BRPF1
Protein name: Peregrin (Bromodomain and
List of molecules and drugs that interact with protein P55201
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P55201_12Q | 12Q | DB04580 | 11820 | CHEMBL216146 | 1-METHYLQUINOLIN-2(1H)-ONE | n/a | IC50(nM) = 4800.0 |
| 2 | P55201_4K8 | 4K8 | n/a | 124656 | CHEMBL1728638 | isoquinoline-3-carboxylic acid | n/a | |
| 3 | P55201_4YO | 4YO | n/a | 66911307 | CHEMBL3818063 | 6-bromo-3,4-dihydroquinoxalin-2(1H)-one | n/a | |
| 4 | P55201_4YS | 4YS | n/a | 10284;5280918; | CHEMBL339695 | isoquinolin-1(2H)-one | n/a | |
| 5 | P55201_4YT | 4YT | n/a | 723138 | n/a | 1-ethyl-8-methoxy-5-methyl[1,2,4]triazolo[4,3-a]quinoline | n/a | |
| 6 | P55201_5GT | 5GT | n/a | 5311897 | CHEMBL3818199 | 7-(trifluoromethyl)-3,4-dihydroquinoxalin-2(1H)-one | n/a | |
| 7 | P55201_5GU | 5GU | n/a | 24707978 | n/a | 7-bromo-3,4-dihydroquinoxalin-2(1H)-one | n/a | |
| 8 | P55201_5GV | 5GV | n/a | 51691340 | CHEMBL3819225 | (2R)-2-ethyl-3-oxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylic acid | n/a | |
| 9 | P55201_5JL | 5JL | n/a | 85223;2366465; | CHEMBL1416049 | 2,8-dithioxo-1,2,3,7,8,9-hexahydro-6H-purin-6-one | n/a | |
| 10 | P55201_5JQ | 5JQ | n/a | 85222;3034255; | CHEMBL3818787 | 2-thioxo-2,3,7,9-tetrahydro-1H-purine-6,8-dione | n/a | |
| 11 | P55201_5Q0 | 5Q0 | n/a | 135441757 | CHEMBL589127 | quinolin-5-ol | n/a | |
| 12 | P55201_5QX | 5QX | n/a | 21297195 | CHEMBL3819561 | 1-methyl-3,4-dihydroquinoxalin-2-one | n/a | |
| 13 | P55201_5QY | 5QY | n/a | 7062175 | CHEMBL3818285 | (3~{S})-3-methyl-3,4-dihydro-1~{H}-quinoxalin-2-one | n/a | |
| 14 | P55201_5RN | 5RN | n/a | 12802 | CHEMBL553944 | 1-(1~{H}-indol-3-yl)ethanone | n/a | |
| 15 | P55201_5RO | 5RO | n/a | 29919653 | CHEMBL3817859 | 1-(7-methyl-1~{H}-indol-3-yl)ethanone | n/a | |
| 16 | P55201_5S9 | 5S9 | n/a | 1509154 | CHEMBL3818519 | ~{N}-[2,4-bis(fluoranyl)phenyl]-2-methyl-pyrazole-3-carboxamide | n/a | |
| 17 | P55201_5SB | 5SB | n/a | 39782527 | n/a | ~{N}-[5-(1~{H}-pyrazol-4-yl)quinolin-8-yl]ethanamide | n/a | |
| 18 | P55201_5SG | 5SG | n/a | 30386 | CHEMBL57481 | isoquinolin-5-ol | n/a | |
| 19 | P55201_5SH | 5SH | n/a | 13651 | CHEMBL109074 | 4-phenylpyridine | n/a | |
| 20 | P55201_5SJ | 5SJ | n/a | 95788991 | n/a | ethyl (2~{R})-2-methyl-3-oxidanylidene-2,4-dihydro-1~{H}-quinoxaline-6-carboxylate | n/a | |
| 21 | P55201_5SK | 5SK | n/a | 802065 | n/a | ~{N}-[(2~{R})-butan-2-yl]-1-methyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine | n/a | |
| 22 | P55201_5SN | 5SN | n/a | 266107 | n/a | 1,5-dimethyl-[1,2,4]triazolo[4,3-a]quinoline | n/a | |
| 23 | P55201_5XD | 5XD | n/a | 20962022 | n/a | 4-ethyl-~{N}-(6-methoxy-1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)benzenesulfonamide | n/a | |
| 24 | P55201_5XE | 5XE | n/a | 35397514 | CHEMBL3770173 | 4-bromanyl-~{N}-(6-methoxy-1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)-2-methyl-benzenesulfonamide | n/a | |
| 25 | P55201_5XF | 5XF | n/a | 40642506 | CHEMBL3356143 | ~{N}-(1,3-dimethyl-2-oxidanylidene-6-pyrrolidin-1-yl-benzimidazol-5-yl)-2-methoxy-benzamide | n/a | |
| 26 | P55201_8VI | 8VI | n/a | 121232406 | CHEMBL3827932 | N-[1,3-dimethyl-6-[(2R)-2-methylpiperazin-1-yl]-2-oxidanylidene-benzimidazol-5-yl]-N-ethyl-2-methoxy-benzamide | n/a | |
| 27 | P55201_9F9 | 9F9 | n/a | 15990224 | CHEMBL1522313 | N-[1,3-dimethyl-2-oxo-6-(piperidin-1-yl)-2,3-dihydro-1H-benzimidazol-5-yl]-2-methoxybenzamide | n/a | |
| 28 | P55201_9KT | 9KT | n/a | 351421 | CHEMBL4281139 | 1,4-dimethylquinoxaline-2,3-dione | n/a | |
| 29 | P55201_9KW | 9KW | n/a | 20944522 | CHEMBL4286098 | ~{N}-[1,4-dimethyl-7-morpholin-4-yl-2,3-bis(oxidanylidene)quinoxalin-6-yl]-5,6,7,8-tetrahydronaphthalene-2-sulfonamide | n/a | |
| 30 | P55201_9L5 | 9L5 | n/a | 51940266 | n/a | ~{N}-[(1~{S})-1-(1,5-dimethylpyrazol-4-yl)ethyl]-1-ethyl-3-methyl-2-oxidanylidene-quinoxaline-6-carboxamide | n/a | |
| 31 | P55201_9LK | 9LK | n/a | 71866920 | CHEMBL4282392 | ~{N}-[6-(4-chloranylphenoxy)pyridin-3-yl]-2,4-dimethyl-1,3-oxazole-5-carboxamide | n/a | |
| 32 | P55201_9LN | 9LN | n/a | 41606711 | CHEMBL4293001 | 1-ethyl-~{N}-methyl-2,3-bis(oxidanylidene)-~{N}-[(1-phenylpyrazol-4-yl)methyl]-4~{H}-quinoxaline-6-carboxamide | n/a | |
| 33 | P55201_9LT | 9LT | n/a | 25368302 | n/a | 1-ethyl-~{N}-[(~{R})-(3-fluorophenyl)-(1-methylimidazol-2-yl)methyl]-2,3-bis(oxidanylidene)-4~{H}-quinoxaline-6-carboxamide | n/a | |
| 34 | P55201_AXN | AXN | n/a | 20946727 | CHEMBL4292834 | ~{N}-[1,4-dimethyl-2,3-bis(oxidanylidene)-7-pyrrolidin-1-yl-quinoxalin-6-yl]-4-(2-methylpropyl)benzenesulfonamide | n/a | |
| 35 | P55201_AYW | AYW | n/a | 8073277 | n/a | 4-methyl-6-oxidanyl-1-benzofuran-3-one | n/a | |
| 36 | P55201_B0E | B0E | n/a | 5396150 | CHEMBL4472996 | 1,3-bis(oxidanyl)benzo[c]chromen-6-one | n/a | |
| 37 | P55201_B0H | B0H | n/a | 95904878 | n/a | ~{N}-[4-[[(3~{S},5~{R})-3,5-dimethylpiperidin-1-yl]methyl]-1,3-thiazol-2-yl]-2,4-dimethyl-1,3-oxazole-5-carboxamide | n/a | |
| 38 | P55201_BEA | BEA | DB02891 | 449237 | n/a | 5-METHYL-1,2,4-TRIAZOLO[3,4-B]BENZOTHIAZOLE | n/a | |
| 39 | P55201_BMF | BMF | n/a | 72943187 | CHEMBL3133807 | Bromosporine | n/a | |
| 40 | P55201_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 41 | P55201_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 42 | P55201_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 43 | P55201_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 44 | P55201_FMT | FMT | DB01942 | 284;18971002; | CHEMBL116736 | FORMIC ACID | n/a | |
| 45 | P55201_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 46 | P55201_K | K | n/a | 813 | CHEMBL1233793 | POTASSIUM ION | n/a | |
| 47 | P55201_KGU | KGU | n/a | 46249496 | n/a | ~{N}-[1,4-diethyl-2,3-bis(oxidanylidene)-7-piperidin-1-yl-quinoxalin-6-yl]-2-(4-methylpiperazin-1-yl)ethanamide | n/a | |
| 48 | P55201_LF1 | LF1 | n/a | 121232405 | CHEMBL3828191 | N-[1,3-dimethyl-6-[(2R)-2-methylpiperazin-1-yl]-2-oxidanylidene-benzimidazol-5-yl]-2-methoxy-benzamide | n/a | |
| 49 | P55201_LS8 | LS8 | n/a | 91827373 | CHEMBL3752151 | 4-cyano-~{N}-(1,3-dimethyl-2-oxidanylidene-quinolin-6-yl)-2-methoxy-benzenesulfonamide | n/a | |
| 50 | P55201_N48 | N48 | n/a | 118933136 | CHEMBL4096095 | 4-cyano-N-(7-methoxy-1,4-dimethyl-2-oxo-1,2-dihydroquinolin-6-yl)benzene-1-sulfonamide | n/a | |
| 51 | P55201_NO3 | NO3 | DB14049 | 943 | CHEMBL186200 | NITRATE ION | n/a | |
| 52 | P55201_UNX | UNX | n/a | |||||
| 53 | P55201_UWX | UWX | n/a | 16026457 | CHEMBL1360726 | ~{N}-[1,4-dimethyl-7-morpholin-4-yl-2,3-bis(oxidanylidene)quinoxalin-6-yl]-4-(2-methylpropyl)benzenesulfonamide | n/a | |
| 54 | P55201_WGX | WGX | n/a | 20946705 | CHEMBL4282532 | ~{N}-[1,4-dimethyl-2,3-bis(oxidanylidene)-7-piperidin-1-yl-quinoxalin-6-yl]-5,6,7,8-tetrahydronaphthalene-2-sulfonamide | n/a | |
| 55 | P55201_XZ8 | XZ8 | n/a | 6937521 | CHEMBL3810303 | 4-(1-acetyl-1H-indol-3-yl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one | n/a | |
| 56 | P55201_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 57 | P55201_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a |